This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination.
Cell reports · 2026 · senior author
Dickkopf-1 release by the bone marrow upon ischemic stroke bridges neurovascular and immune deregulations.
Brain, behavior, and immunity · 2026
Cellular rejuvenation protects neurons from inflammation-mediated cell death.
Cell reports · 2025
Latest funding
- $1,021,276
Defining the roles of Mef2 transcription factors in coordinating microglia support and neuroprotective functions in brain health and diseases.
CIHR · 2026 · Nominated PI
- $105,000
Determining the role of transcription factor Irf5 in regulating microglial transcriptional and cellular activities in the demyelinating brain
CIHR · 2021 · Supervisor
- $883,575
Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in demyelinating brain disorders.
CIHR · 2020 · Nominated PI
27 publications.
Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination.
Distéfano-Gagné F, Belhamiti N, Saxon W, Bitarafan S, Xavier AM, Fiola S, Rivest S, Gosselin D
Dickkopf-1 release by the bone marrow upon ischemic stroke bridges neurovascular and immune deregulations.
Menet R, Bernard M, Lecordier S, Trudel E, Allain AS, Distéfano-Gagné F, Seigneur J, Aldib N, Haili Y, Bretzner F, Gosselin D, ElAli A
Cellular rejuvenation protects neurons from inflammation-mediated cell death.
Drake SS, Mohammadnia A, Zaman A, Gianfelice C, Heale K, Groh AMR, Hua EM, Hintermayer MA, Lu YR, Gosselin D, Zandee S, Prat A, Stratton JA, Sinclair DA, Fournier AE
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.
Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK
Roles and regulation of microglia activity in multiple sclerosis: insights from animal models.
Distéfano-Gagné F, Bitarafan S, Lacroix S, Gosselin D
PRMT1 is required for the generation of MHC-associated microglia and remyelination in the central nervous system.
Lee J, Villarreal OD, Wang YC, Ragoussis J, Rivest S, Gosselin D, Richard S
Context-dependent transcriptional regulation of microglial proliferation.
Belhocine S, Machado Xavier A, Distéfano-Gagné F, Fiola S, Rivest S, Gosselin D
Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties.
Mishra MK, Rawji KS, Keough MB, Kappen J, Dowlatabadi R, Vogel HJ, Chopra S, Distéfano-Gagné F, Dufour A, Gosselin D, Yong VW
Altered expression of fractalkine in HIV-1-infected astrocytes and consequences for the virus-related neurotoxicity.
Sénécal V, Barat C, Gagnon MT, Vanasse F, Leboeuf M, Gosselin D, Tremblay MJ
Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis.
Chignon A, Rosa M, Boulanger MC, Argaud D, Devillers R, Bon-Baret V, Mkannez G, Li Z, Rufiange A, Gaudreault N, Gosselin D, Thériault S, Bossé Y, Mathieu P
Defining the roles of Mef2 transcription factors in coordinating microglia support and neuroprotective functions in brain health and diseases.
Principal investigators: Gosselin, David
Keywords: Brain Functions; Flow Cytometry; Mef2 Transcription Factors; Microglia; Microscopy; Mouse; Neurodegenerative Disorders; Neuroinflammation; Rna-Seq, Chip-Seq; Transcription
Determining the role of transcription factor Irf5 in regulating microglial transcriptional and cellular activities in the demyelinating brain
Principal investigators: Distéfano-Gagné, Félix
Keywords: Chip-Seq; Flow Cytometry; Irf5; Massively Parallel Sequencing; Microglia; Microscopy; Mouse Model; Multiple Sclerosis; Myelin; Rna-Seq
Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in demyelinating brain disorders.
Principal investigators: Gosselin, David
Keywords: Atac-Seq; Chip-Seq; Distal Genomic Regulatory Elements; Epigenomics; Interferon Regulatory Factors; Microglia; Mouse; Neurodegenerative Diseases; Rna-Seq; Transcription
Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in chronic neurodegenerative diseases.
Principal investigators: Gosselin, David
Keywords: Atac-Seq; Chip-Seq; Distal Genomic Regulatory Elements; Epigenomics; Interferon Regulatory Factors; Microglia; Mouse; Neurodegenerative Diseases; Rna-Seq; Transcription
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Serge Rivest and Ayman ElAli: 13 shared papers
- Serge Rivest and David Gosselin: 13 shared papers
- Guy Boivin and Serge Rivest: 8 shared papers
- Serge Rivest and Steve Lacroix: 3 shared papers
- Guy Boivin and David Gosselin: 2 shared papers
- Alexandre Prat and Serge Rivest: 1 shared paper
- Alexandre Prat and David Gosselin: 1 shared paper
- Serge Rivest and Nathalie Lamarche-Vane: 1 shared paper
- Patrick Mathieu and David Gosselin: 1 shared paper
- Steve Lacroix and David Gosselin: 1 shared paper
- Nathalie Lamarche-Vane and David Gosselin: 1 shared paper
- Antoine Dufour and David Gosselin: 1 shared paper
- Ayman ElAli and David Gosselin: 1 shared paper
- Médecine moléculaire
- Molecular Medicine
- Pediatrics
- Neurosciences
- Microbiology and Infectious Diseases
- Anatomy and Cell Biology
- Surgery
- Other
Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Serge Rivest
Molecular Medicine
13 shared papers, latest 2026
Guy Boivin
Pediatrics
2 shared papers, latest 2012
Patrick Mathieu
Surgery
1 shared papers, latest 2021
Steve Lacroix
Médecine moléculaire
1 shared papers, latest 2023
Nathalie Lamarche-Vane
Anatomy and Cell Biology
1 shared papers, latest 2020
Antoine Dufour
Microbiology and Infectious Diseases
1 shared papers, latest 2021
Ayman ElAli
Faculty
1 shared papers, latest 2026
Alexandre Prat
Neurosciences
1 shared papers, latest 2025
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