Faculty profile

Serge Rivest

ResearcherMolecular MedicineUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Serge Rivest

Researcher

Molecular Medicine

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
20 publications in the last five years, latest in 2026.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (7 CIHR, 2 NSERC), most recently in 2022.
Supervised 2 trainees who won CIHR awards, most recently in 2014.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

125

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Crc Alzheimer'S Disease Innate Immunity Microglia Monocytes Multiple Sclerosis Immunotherapy Neuroinflammation

Latest papers

Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination.
Cell reports · 2026
Describing the First Canadian Cohort of Oculogastrointestinal Neurodevelopmental Syndrome Caused by CAPN15 Pathogenic Variants.
American journal of medical genetics. Part A · 2025
Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-β Pathology in APP/PS1 Mice.
Journal of Alzheimer's disease : JAD · 2024

All 125 publications

Latest funding

Canada Research Chair - Tier 1
CIHR · 2022 · Nominated PI
$1,400,000
Canada Research Chair Tier 1
CIHR · 2015 · Nominated PI
$1,400,000
Le rôle de l'âge et de la diète riche en gras dans la pathophysiologie de la maladie d'Alzheimer
CIHR · 2014 · Supervisor
$105,000

All 12 grants and awards

125 publications.

Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination.

Distéfano-Gagné F, Belhamiti N, Saxon W, Bitarafan S, Xavier AM, Fiola S, Rivest S, Gosselin D

Cell reports2026

DOI: 10.1016/j.celrep.2026.117569 PMID: 42319825

Describing the First Canadian Cohort of Oculogastrointestinal Neurodevelopmental Syndrome Caused by CAPN15 Pathogenic Variants.

Lin E, Cruz-Marino T, Chrestian N, Leblanc J, Rioux N, Labrie Y, Rivest S, Lace B, Colaiacovo S, Saleh M

American journal of medical genetics. Part A2025

DOI: 10.1002/ajmg.a.64133 PMID: 40485323

Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-β Pathology in APP/PS1 Mice.

Lapeyre L, Piret J, Rhéaume C, Pons V, Uyar O, Préfontaine P, Rivest S, Boivin G

Journal of Alzheimer's disease : JAD2024

DOI: 10.3233/jad-230746 PMID: 38143354

The evolution of mesenchymal stem cell-derived neural progenitor therapy for Multiple Sclerosis: from concept to clinic.

Ghareghani M, Arneaud A, Rivest S

Frontiers in cellular neuroscience2024Senior author

DOI: 10.3389/fncel.2024.1428652 PMID: 39280795

Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease.

Martínez-Drudis L, Bérard M, Musiol D, Rivest S, Oueslati A

Heliyon2024

DOI: 10.1016/j.heliyon.2024.e39571 PMID: 39498012

Multiple Sclerosis Research Evolves: A Closer Look at Deep Gray Matter, Sexual Function Rehabilitation, and T Regulatory Cells.

Ghareghani M, Rivest S

Journal of personalized medicine2024Senior author

DOI: 10.3390/jpm14020202 PMID: 38392635

Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis.

Ghareghani M, Pons V, Laflamme N, Zibara K, Rivest S

Experimental & molecular medicine2023Senior author

DOI: 10.1038/s12276-023-00925-1 PMID: 36635431

The Synergistic Potential of Combining PD-1/PD-L1 Immune Checkpoint Inhibitors with NOD2 Agonists in Alzheimer's Disease Treatment.

Ghareghani M, Rivest S

International journal of molecular sciences2023Senior author

DOI: 10.3390/ijms241310905 PMID: 37446081

Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis.

Ghareghani M, Zibara K, Rivest S

Proceedings of the National Academy of Sciences of the United States of America2023Senior author

DOI: 10.1073/pnas.2219334120 PMID: 36972442

Author Correction: Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis.

Ghareghani M, Pons V, Laflamme N, Zibara K, Rivest S

Experimental & molecular medicine2023Senior author

DOI: 10.1038/s12276-023-00948-8 PMID: 36828932

Canada Research Chair - Tier 1

Nominated PICIHR2022Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Rivest, Serge

Keywords: Crc

$1,400,000

Canada Research Chair Tier 1

Nominated PICIHR2015Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Rivest, Serge

Keywords: Crc

$1,400,000

Le rôle de l'âge et de la diète riche en gras dans la pathophysiologie de la maladie d'Alzheimer

SupervisorCIHR2014Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Thériault, Peter

Keywords: Barrière Hémato-Encéphalique; Bèta-Amyloïde; Diète Riche En Gras; Immunité Innée; Maladie D'Alzheimer; Microglies; Monocytes; Neuroinflammation; Unité Neurovasculaire; Vieillissement

$105,000

Therapeutic properties of innate immune cells and system for brain diseases.

Nominated PICIHR2014Foundation Grant

Principal investigators: Rivest, Serge

Keywords: Alzheimer'S Disease; Immunotherapy; Innate Immunity; Microglia; Monocytes; Multiple Sclerosis; Neuroinflammation; Neuroprotection; Preclinical Mouse Models; The Neurovascular Unit

$3,524,317

Divergent inflammatory response in Alzheimer's disease and multiple sclerosis: Molecular determinants and basis for novel therapies.

Nominated PICIHR2012Team Grant: Health Challenges in Chronic Inflammation Initiative (LOI)

Principal investigators: Rivest, Serge

Keywords: Alzheimer'S Disease; Brain; Gene Expression; Inflammation; Innate Immunity; Microglia; Monocytes; Mouse Models; Multiple Sclerosis; Transcriptome

Développement de nouvelles immunothérapies ciblant les Toll-like receptors (TLRs) pour traiter la maladie d'Alzheimer

SupervisorCIHR2011Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Michaud, Jean-Philippe

Keywords: Amyloid Beta; Cytométrie De Flux; Hybridation In Situ; Immunohistochimie; Maladie D'Alzheimer; Microglie; Microscopie Et Imagerie; Modèles Animaux Transgéniques; Neuroimmunologie; Toll-Like Receptors

$105,000

Novel immunotherapies for treating Alzheimer's disease

Nominated PICIHR2011Operating Grant: Industry-partnered Collaborative Research - Rx&D partner

Principal investigators: Rivest, Serge

Keywords: Adjuvants; Alzheimer'S Disease; Amyloid Cascade; Immunization; Mouse Models; Toll-Like Receptors; Vaccine

$571,200

Therapeutic properties of the innate immune response by microglia

Nominated PICIHR2010Operating Grant

Principal investigators: Rivest, Serge

Keywords: Adjuvants; Brain Repair; Cell Proliferation; Microglia; Mouse Models; Neuroprotection; New Drugs; Toll-Like Receptors

$827,020

Molecular mechanisms involved in the neuroendocrine-immune interaction

Nominated PICIHR2009Operating Grant

Principal investigators: Rivest, Serge

Keywords: Glucocorticoids (Hpa Axis); Inflammation/Infection/Cytokines; Molecular Neurobiology; Neuroendocrinology; Neuronal Circuits; Transgenic Mice

$917,050

LHRH neuronal activity and gene transcription during the ovulatory cycle and stress

Principal investigatorNSERC1998Discovery Grants Program - Individual

Principal investigators: Rivest, Serge

$118,690

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Serge Rivest

Research

Latest papers

Latest funding

Multi-tier signaling and chromatin remodeling coordinate microglia inflammatory states and activities associated with demyelination.

Describing the First Canadian Cohort of Oculogastrointestinal Neurodevelopmental Syndrome Caused by CAPN15 Pathogenic Variants.

Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-&#x3b2; Pathology in APP/PS1 Mice.

The evolution of mesenchymal stem cell-derived neural progenitor therapy for Multiple Sclerosis: from concept to clinic.

Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease.

Multiple Sclerosis Research Evolves: A Closer Look at Deep Gray Matter, Sexual Function Rehabilitation, and T Regulatory Cells.

Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis.

The Synergistic Potential of Combining PD-1/PD-L1 Immune Checkpoint Inhibitors with NOD2 Agonists in Alzheimer's Disease Treatment.

Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis.

Author Correction: Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis.

LHRH neuronal activity and gene transcription during the ovulatory cycle and stress

Frequent collaborators

Ayman ElAli

David Gosselin

Guy Boivin

Arnaud Droit

Jean Gosselin

Steve Lacroix

Ji Zhang

Manu Rangachari

Abid Oueslati

Serge Rivest

Denis Soulet

Martin Parent

Nathalie Lamarche-Vane

Marie-Ève Tremblay

Jean-Pierre Julien

Yves De Koninck

Marcelo Gottschalk

Mariela Segura

Lisa Topolnik

Giamal Luheshi

Marcelo Gottschalk

Mariela Segura

Patrick Provost

Alexandre Prat

Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-β Pathology in APP/PS1 Mice.