Faculty profile

Jacques Simard

ResearcherUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Jacques Simard

Researcher

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
55 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

215

Publications

548

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Breast Cancer Biostatistics And Bioinformatics Functional Assessment Of Genetic Variants Genetic Epidemiology Genetic Susceptibility High-Throughput Massively Parallel Sequencing Personalized Risk Assessment Risk Prediction Model

Latest papers

Genetic counseling services for hereditary breast and ovarian cancer: patients' experience and satisfaction with different service models.
European journal of human genetics : EJHG · 2026
PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups.
medRxiv : the preprint server for health sciences · 2026
Canadian Women’s Attitudes Toward Receiving Personalized Breast Cancer Risk Information: Insights From the PERSPECTIVE I&I Project
Clinical Breast Cancer · 2026

All 215 publications

Latest funding

Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays.
CIHR · 2023 · Nominated PI
$1,093,950
Impacts of evolving demography and socio-economic status on assessment of genetic risks
SSHRC · 2017 · Co-investigator
$202,000
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation
CIHR · 2017 · Nominated PI
$4,900,000

All 7 grants and awards

From the 150 most recent of 215 publications.

Genetic counseling services for hereditary breast and ovarian cancer: patients' experience and satisfaction with different service models.

Haroun O, Lapointe J, Guérard R, Bergeron AS, Raîche C, Chiquette J, Bouchard K, Pomey MP, Hébert J, Olivier Chevrier G, Lachapelle P, Omeranovic A, Côté M, Boily L, Brisson C, Gekas J, Cruz-Marino T, Touhami O, Blanchet Saint-Pierre A, Gagnon S, Boisvert K, Brousseau C, Castonguay L, Gosselin I, Renaud MC, Ruiz Mangas MG, Paquet-Beaupré A, Bélanger ME, Racine MM, Roy MC, Blanchette S, Faucher V, Leblanc J, Dubeau ME, Cavaillé M, Plante M, Desbiens C, Beaumont M, Simard J, Dorval M, Nabi H

European journal of human genetics : EJHG2026

DOI: 10.1038/s41431-026-02031-y PMID: 41699267

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups.

Levi H, Wang Q, Bolla MK, Dennis J, Andrulis IL, Antonenkova N, Au CH, Augustinsson A, Beane Freeman LE, Behrens S, Bermisheva M, Bodelon C, Bogdanova NV, Bojesen SE, Brenner H, Brock IW, Brüning T, Byers H, Camp NJ, Castelao JE, Choi JY, Chung WK, NBCS Collaborators, Colonna SV, Couch FJ, Czene K, Daly MB, Devilee P, Dörk T, Eliassen AH, Eriksson M, Evans DG, Fasching PA, Faw K, Gago-Dominguez M, García-Closas M, Haiman CA, Hamann U, Hartman M, Ho V, Ho PJ, Hooning MJ, Hoppe R, Howell SJ, ABCTB Investigators, SGBCC Investigators, Ito H, Iwasaki M, Jakubowska A, Jernström H, Joseph V, Kaaks R, Kang D, Khusnutdinova EK, Kiprijanovska S, Koutros S, Kristensen VN, Kurian AW, Kwong A, Lambrechts D, Larson NL, Marchand LL, Li S, Li J, Lophatananon A, Mannermaa A, Matsuo K, Maxwell W, Muir K, Nevelsteen I, Obi N, O'Brien KM, Offit K, Ottewell PD, Patel AV, Peterlongo P, Plaseska-Karanfilska D, Prajzendanc K, Radice P, Ramachandran D, Rashid MU, Romero A, Saloustros E, Sandler DP, Schöttker B, Simard J, Southey MC, Stone J, Sugier PE, Taylor JA, Teras LR, Truong T, Weinberg CR, Yadav S, Yamaji T, Zheng W, Dunning AM, Mavaddat N, Easton DF, Michailidou K, Elkon R, Shamir R

medRxiv : the preprint server for health sciences2026

DOI: 10.64898/2026.07.12.26357860 PMID: 42523604

Canadian Women’s Attitudes Toward Receiving Personalized Breast Cancer Risk Information: Insights From the PERSPECTIVE I&I Project

Brooks JD, Blackmore KM, Ngo NNM, Walker MJ, Chang A, Lambert-Côté L, Turgeon A, Lofters AK, Nabi H, Antoniou AC

Clinical Breast Cancer20262 citations

DOI: 10.1016/j.clbc.2025.12.009

Perspectives from a multi-stakeholder workshop for implementing a risk-stratified breast cancer screening program in Canada

Safieh-Garabedian N, Antoniou AC, Brooks J, Carroll J, Cavaillé M, Chiquette J, DeCoteau M, Doyle G, Eisen A, Eloy L

Communications Medicine2026

DOI: 10.1038/s43856-026-01582-x

Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project

Yang X, Usher-Smith JA, Blackmore KM, Brooks JD, Bell KA, Carver T, Chang A, Chiquette J, Easton DF, Eisen A

Cancers2026Senior author

DOI: 10.3390/cancers18091482

Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer.

Hoppe R, Winter S, Lo WY, Michailidou K, Bolla MK, Keeman R, Wang Q, Dennis J, Lush M, Kalari KR, Goetz MP, Wang L, Cairns J, Weinshilboum R, Shepherd L, Chen BE, Häberle L, Ruebner M, Beckmann MW, He W, Larson NL, Armasu SM, Schroth W, Chowbay B, Khor CC, Abubakar M, Antoniou AC, Brüning T, Castelao JE, Chang-Claude J, Nbcs Collaborators, Dörk T, Eccles DM, Figueroa JD, Gago-Dominguez M, García-Sáenz JA, Gündert M, Hack CC, Hamann U, Han S, Hooning MJ, Huebner H, Abctb Investigators, John EM, Ko YD, Kristensen VN, Linn S, Margolin S, Mavroudis D, Nevanlinna H, Neven P, Obi N, Park-Simon TW, Pylkäs K, Rashid MU, Romero A, Saloustros E, Sawyer EJ, Tapper WJ, Tomlinson I, Wendt C, Winqvist R, Dunning AM, Simard J, Hall P, Pharoah PDP, Schwab M, Couch FJ, Czene K, Fasching PA, Easton DF, Schmidt MK, Ingle JN, Brauch H

NPJ breast cancer2025

DOI: 10.1038/s41523-025-00733-y PMID: 39971965

Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers.

Tai MC, Dennis J, Park SK, Kim SW, Lee JW, Hassan NT, Kwong A, Hartman M, Yoon SY, Ngeow J, Woo YL, Park B, Wong ZL, Leslie G, Bolla MK, Barnes DR, Parsons MT, Soucy P, Simard J, Mohd Taib NA, Yip CH, Easton DF, Chenevix-Trench G, Antoniou AC, Teo SH, Ho WK

NPJ breast cancer2025

DOI: 10.1038/s41523-025-00820-0 PMID: 41027929

Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M, Bjorge L, Blomqvist C, Blot W, Bogdanova N, Bojesen A, Bojesen SE, Bolla MK, Bonanni B, Børresen-Dale AL, Brauch H, Brennan P, Brenner H, Bruinsma F, Brunet J, Buhari SA, Burwinkel B, Butzow R, Buys SS, Cai Q, Caldes T, Campbell I, Cannioto R, Chang-Claude J, Chiquette J, Choi JY, Claes KBM, GEMO Study Collaborators, Cook LS, Cox A, Cramer DW, Cross SS, Cybulski C, Czene K, Daly MB, Damiola F, Dansonka-Mieszkowska A, Darabi H, Dennis J, Devilee P, Diez O, Doherty JA, Domchek SM, Dorfling CM, Dörk T, Dumont M, Ehrencrona H, Ejlertsen B, Ellis S, EMBRACE, Engel C, Lee E, Evans DG, Fasching PA, Feliubadalo L, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Foretova L, Fostira F, Foulkes WD, Fridley BL, Friedman E, Frost D, Gambino G, Ganz PA, Garber J, García-Closas M, Gentry-Maharaj A, Ghoussaini M, Giles GG, Glasspool R, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Goode EL, Goodman MT, Greene MH, Gronwald J, Guénel P, Haiman CA, Hall P, Hallberg E, Hamann U, Hansen TVO, Harrington PA, Hartman M, Hassan N, Healey S, Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON), Heitz F, Herzog J, Høgdall E, Høgdall CK, Hogervorst FBL, Hollestelle A, Hopper JL, Hulick PJ, Huzarski T, Imyanitov EN, KConFab Investigators, Australian Ovarian Cancer Study Group, Isaacs C, Ito H, Jakubowska A, Janavicius R, Jensen A, John EM, Johnson N, Kabisch M, Kang D, Kapuscinski M, Karlan BY, Khan S, Kiemeney LA, Kjaer SK, Knight JA, Konstantopoulou I, Kosma VM, Kristensen V, Kupryjanczyk J, Kwong A, de la Hoya M, Laitman Y, Lambrechts D, Le N, De Leeneer K, Lester J, Levine DA, Li J, Lindblom A, Long J, Lophatananon A, Loud JT, Lu K, Lubinski J, Mannermaa A, Manoukian S, Le Marchand L, Margolin S, Marme F, Massuger LFAG, Matsuo K, Mazoyer S, McGuffog L, McLean C, McNeish I, Meindl A, Menon U, Mensenkamp AR, Milne RL, Montagna M, Moysich KB, Muir K, Mulligan AM, Nathanson KL, Ness RB, Neuhausen SL, Nevanlinna H, Nord S, Nussbaum RL, Odunsi K, Offit K, Olah E, Olopade OI, Olson JE, Olswold C, O'Malley D, Orlow I, Orr N, Osorio A, Park SK, Pearce CL, Pejovic T, Peterlongo P, Pfeiler G, Phelan CM, Poole EM, Pylkäs K, Radice P, Rantala J, Rashid MU, Rennert G, Rhenius V, Rhiem K, Risch HA, Rodriguez G, Rossing MA, Rudolph A, Salvesen HB, Sangrajrang S, Sawyer EJ, Schildkraut JM, Schmidt MK, Schmutzler RK, Sellers TA, Seynaeve C, Shah M, Shen CY, Shu XO, Sieh W, Singer CF, Sinilnikova OM, Slager S, Song H, Soucy P, Southey MC, Stenmark-Askmalm M, Stoppa-Lyonnet D, Sutter C, Swerdlow A, Tchatchou S, Teixeira MR, Teo SH, Terry KL, Terry MB, Thomassen M, Tibiletti MG, Tihomirova L, Tognazzo S, Toland AE, Tomlinson I, Torres D, Truong T, Tseng CC, Tung N, Tworoger SS, Vachon C, van den Ouweland AMW, van Doorn HC, van Rensburg EJ, Van't Veer LJ, Vanderstichele A, Vergote I, Vijai J, Wang Q, Wang-Gohrke S, Weitzel JN, Wentzensen N, Whittemore AS, Wildiers H, Winqvist R, Wu AH, Yannoukakos D, Yoon SY, Yu JC, Zheng W, Zheng Y, Khanna KK, Simard J, Monteiro AN, French JD, Couch FJ, Freedman ML, Easton DF, Dunning AM, Pharoah PD, Edwards SL, Chenevix-Trench G, Antoniou AC, Gayther SA

Nature communications2025

DOI: 10.1038/s41467-025-63507-x PMID: 40925936

Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries.

Ho PJ, Loo CKY, Goh MH, Abubakar M, Ahearn TU, Andrulis IL, Antonenkova NN, Aronson KJ, Augustinsson A, Behrens S, Bodelon C, Bogdanova NV, Bolla MK, Brantley K, Brenner H, Byers H, Camp NJ, Castelao JE, Cessna MH, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Choi JY, Colonna SV, Czene K, Daly MB, Derouane F, Dörk T, Eliassen AH, Engel C, Eriksson M, Evans DG, Fletcher O, Fritschi L, Gago-Dominguez M, Genkinger JM, Geurts-Giele WRR, Glendon G, Hall P, Hamann U, Ho CYS, Ho WK, Hooning MJ, Hoppe R, Howell A, Humphreys K, ABCTB Investigators, kConFab Investigators, SGBCC Investigators, MyBrCa Investigators, Ito H, Iwasaki M, Jakubowska A, Jernström H, John EM, Johnson N, Kang D, Kim SW, Kitahara CM, Ko YD, Kraft P, Kwong A, Lambrechts D, Larsson S, Li S, Lindblom A, Linet M, Lissowska J, Lophatananon A, MacInnis RJ, Mannermaa A, Manoukian S, Margolin S, Matsuo K, Michailidou K, Milne RL, Taib NAM, Muir K, Murphy RA, Newman WG, O'Brien KM, Obi N, Olopade OI, Panayiotidis MI, Park SK, Park-Simon TW, Patel AV, Peterlongo P, Plaseska-Karanfilska D, Pylkäs K, Rashid MU, Rennert G, Rodriguez J, Saloustros E, Sandler DP, Sawyer EJ, Scott CG, Shahi S, Shu XO, Shulman K, Simard J, Southey MC, Stone J, Taylor JA, Teo SH, Teras LR, Terry MB, Torres D, Vachon CM, Van Houdt M, Verhoeven J, Weinberg CR, Wolk A, Yamaji T, Yip CH, Zheng W, Hartman M, Li J

medRxiv : the preprint server for health sciences2025

DOI: 10.1101/2025.02.27.25323002 PMID: 40093266

Adapting the BOADICEA breast and ovarian cancer risk models for the ethnically diverse UK population.

Ficorella L, Yang X, Mavaddat N, Carver T, Hassan H, Dennis J, Tyrer J, Ho WK, Teo SH, Hartman M, Li J, Eriksson M, Czene K, Hall P, Rahman T, Bacon A, Hardy S, Stokes AE, Stutzin Donoso F, Archer S, Simard J, Pharoah PDP, Usher-Smith JA, Tischkowitz M, Easton DF, Antoniou AC

British journal of cancer2025

DOI: 10.1038/s41416-025-03117-y PMID: 40676226

Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays.

Nominated PICIHR2023Project Grant

Principal investigators: Simard, Jacques R

Keywords: Biostatistics And Bioinformatics; Breast Cancer; Functional Assessment Of Genetic Variants; Genetic Epidemiology; Genetic Susceptibility; High-Throughput Massively Parallel Sequencing; Personalized Risk Assessment; Risk Prediction Model; Site Saturation Mutagenesis

$1,093,950

Impacts of evolving demography and socio-economic status on assessment of genetic risks

Co-investigatorSSHRC2017Insight Grants

Principal investigators: Wolfson, Michael C.

Keywords: demography; cancer; risk stratification; microsimulation; cost-effectiveness

$202,000

Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation

Nominated PICIHR2017Genomics and Personalized Health -Large-Scale Applied Genomics Res Projects

Principal investigators: Simard, Jacques R

Keywords: Breast Cancer

$4,900,000

Canada Research Chair Tier 1

Nominated PICIHR2014Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Simard, Jacques R

Keywords: Crc

$1,400,000

Personalised Risk Stratification for Prevention and Early Detection of Breast Cancer

Nominated PICIHR2012Genomics and Personalized Health

Principal investigators: Simard, Jacques R

Keywords: And Early Detection, Measure; And Women’S Decisions To Use Personalised Health Services; Breast Cancer Risk Assessment; Evidence-Based Knowledge Transfer Tools; Genetic Architecture Of Breast Cancer; Health Promotion Campagne; On Health Professional; Prevention And Risk Reduction Strategies; Risk Communication; Risk Prediction Model Genomic Profiling; Risk Stratification For Breast Cancer Prevention; Socio-Economic Evaluation Of The Impact Of Personalised; The Effect Of Improved Breast Cancer Risk Information

$2,500,000

Genetic epidemiology training in translation of gene discoveries to public health applications for chronic diseases

Co-investigatorCIHR2009Training Grant in Genetic Epidemiology - Letter of Intent

Principal investigators: Rousseau, François

Keywords: Analytical Tools; Chronic Diseases; Genetic Epidemiology; Health Technology Assessment; Knowledge Translation; Public Health; Translational Research

Subvention de formation des IRSC-FRSQ en médecine génétique appliquée

Co-investigatorCIHR2008Training Grant

Principal investigators: Rouleau, Guy A

Keywords: Ateliers De Formation; Génétique Translationnelle; Partenariat Réseaux Frsq; Programme Multi-Institutionnel; Recherche Interdisciplinaire

$1,281,761

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jacques Simard

Research

Latest papers

Latest funding

Genetic counseling services for hereditary breast and ovarian cancer: patients' experience and satisfaction with different service models.

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups.

Canadian Women’s Attitudes Toward Receiving Personalized Breast Cancer Risk Information: Insights From the PERSPECTIVE I&I Project

Perspectives from a multi-stakeholder workshop for implementing a risk-stratified breast cancer screening program in Canada

Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project

Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer.

Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers.

Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

Overlap of high-risk individuals across family history, genetic & non-genetic breast cancer risk models: Analysis of 180,398 women from European & Asian ancestries.

Adapting the BOADICEA breast and ovarian cancer risk models for the ethnically diverse UK population.

Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays.

Impacts of evolving demography and socio-economic status on assessment of genetic risks

Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation

Canada Research Chair Tier 1

Personalised Risk Stratification for Prevention and Early Detection of Breast Cancer

Genetic epidemiology training in translation of gene discoveries to public health applications for chronic diseases

Subvention de formation des IRSC-FRSQ en médecine génétique appliquée

Frequent collaborators

Hermann Nabi

Arnaud Droit

Yann Joly

Francine Durocher

Angela Brooks-Wilson

Michael Wolfson

Angela Brooks-Wilson

Andrea Eisen

Andrea Eisen

Jean-Yves Masson

Anita Bane

Nicole Mittmann

Bartha Knoppers

Irene Andrulis

Christy Woolcott

William Foulkes

Aline Talhouk

Nawaid Usmani

Pavel Hamet

Aisha Lofters

Aisha Lofters

Tracy Stockley

Jennifer Brooks

Geoffrey Liu

Shelley Bull

Kelly Metcalfe

Louis Flamand

David Huntsman

Kiat Tan