Faculty profile

Louis Flamand

ResearcherMicrobiologie et immunologieUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Louis Flamand

Researcher

Microbiologie et immunologie

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
29 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 14 research grants (13 CIHR, 1 SSHRC), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

225

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Platelets Inflammation Cytokines Leukocytes Lipid Mediators Lungs Macrophages Novel Coronavirus

Latest papers

Engineering a Modular PapMV Nanoparticle Vaccine: Comparative Efficacy of a Covalent and a Non-Covalent N-Antigen Vaccine Against Emerging SARS-CoV-2 Variants.
Vaccines · 2026
Megakaryocytes Internalize and Are Activated by Immune Complexes.
Circulation research · 2026
Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses.
PLoS biology · 2026

All 77 publications

Latest funding

Inherited chromosomally-integrated human herpesvirus 6 as a cancer predisposing factor
CIHR · 2025 · Nominated PI
$100,000
Human herpesvirus 6 and chromosomal integration
CIHR · 2022 · Nominated PI
$906,525
COVID-19 Variant Supplement - Understanding the pathogenesis of COVID-19
CIHR · 2021 · Nominated PI
$50,000

All 18 grants and awards

77 publications.

Engineering a Modular PapMV Nanoparticle Vaccine: Comparative Efficacy of a Covalent and a Non-Covalent N-Antigen Vaccine Against Emerging SARS-CoV-2 Variants.

Blanchette LJ, Bolduc M, Woldemariam T, Yousefi M, Rabezanahary H, Olivera-Ugarte SM, Garneau C, Angers M, Shi R, Flamand L, Baz M, Vidal S, Falzarano D, Lemay JF, Leclerc D

Vaccines2026

DOI: 10.3390/vaccines14040349 PMID: 42042825

Megakaryocytes Internalize and Are Activated by Immune Complexes.

Puhm F, Allaeys I, Petito E, Sang Y, Tupin F, Dos Santos Pereira Andrade A, Doré E, Dubuc I, Vaillancourt M, Dieudé M, Hébert MJ, Florea BI, Trépanier P, Washington VA, Senis Y, Fortin PR, Brisson AR, Wolberg AS, Bury L, Flamand L, Boilard E

Circulation research2026

DOI: 10.1161/circresaha.125.327999 PMID: 42299675

Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses.

Mulloy RP, Evseev D, Sharlin N, Bui-Marinos MP, Lacasse É, Dubuc I, Flamand L, Corcoran JA

PLoS biology2026

DOI: 10.1371/journal.pbio.3003646 PMID: 41920932

Human herpesvirus 7 and the risk of developing multiple sclerosis.

Ingvarsson J, Grut V, Gustafsson R, Biström M, Lambert L, Michels BE, Bergström T, Flamand L, Waterboer T, Sundström P

Brain communications2026

DOI: 10.1093/braincomms/fcaf492 PMID: 41523194

PapMV nanoparticles: A novel pathway to SARS-CoV-2 protection, distinct from Imidazoquinolines.

Bolduc M, Saint-Louis P, Carignan D, Garneau C, Breton Y, Pelletier M, Rancourt A, Satoh MS, Sato S, Gilbert M, Rabezanahary H, Baz M, Dubuc I, Flamand L, Leclerc D

Nanomedicine : nanotechnology, biology, and medicine2026

DOI: 10.1016/j.nano.2025.102887 PMID: 41354257

Thykamine™: A New Player in the Field of Anti-Inflammatory Drugs.

Lynde C, Flamand L, McCarty V, Sampalis J

Biomedicines2025

DOI: 10.3390/biomedicines13122938 PMID: 41462950

Endogenous human herpesviruses 6A/B.

Flamand L, Arbuckle J, Bonnafous P, Descamps V, Hill JA, Jarrett R, Jerome K, Kaufer BB, Koide R, Komaroff AL, Medveczky P, Miura H, Mori Y, Parrish N, Pellett PE, Wood M, Yoshikawa T, Zerr DM

Journal of virology2025First author

DOI: 10.1128/jvi.01054-25 PMID: 40748144

A Benchmark of methods for SARS-CoV-2 whole genome sequencing and development of a more sensitive method.

Bayega A, Reiling SJ, Liu JL, Dubuc I, Gravel A, Flamand L, Ragoussis J

Frontiers in genetics2025

DOI: 10.3389/fgene.2025.1516791 PMID: 40893944

No Evidence of Anti-Influenza Nucleoprotein Antibodies in Retail Milk from Across Canada (April-July 2024).

Wallace HL, Wight J, Rzeszutek GJ, Jafri MS, Baz M, Dowding B, Flamand L, Hobman T, Jean F, Joy JB, Lang AS, MacParland S, McCormick C, Noyce R, Russell RS, Sagan SM, Snyman J, Bogoch II, Rasmussen AL, Rimoin AW, Kindrachuk J, Pan-Canadian Milk Study Network

Viral immunology2025

DOI: 10.1089/vim.2025.0029 PMID: 40474813

Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection.

Dos S P Andrade AC, Lacasse E, Dubuc I, Gudimard L, Gravel A, Puhm F, Campolina-Silva G, Queiroz-Junior C, Allaeys I, Prunier J, Azeggouar Wallen O, Dumais É, Belleannée C, Droit A, Flamand N, Boilard É, Flamand L

Proceedings of the National Academy of Sciences of the United States of America2025Senior author

DOI: 10.1073/pnas.2420441122 PMID: 40100623

Inherited chromosomally-integrated human herpesvirus 6 as a cancer predisposing factor

Nominated PICIHR2025Project Grant - Priority Announcement: Early Detection/Cancer Prevention

Principal investigators: Flamand, Louis

Keywords: Cancer Predisposition; Dna Damage; Dna Repair Mechanism; Human Herpesvirus 6; Integrated Viral Genomes

$100,000

Human herpesvirus 6 and chromosomal integration

Nominated PICIHR2022Project Grant

Principal investigators: Flamand, Louis

Keywords: Chromosomal Integration; Human Herpesvirus 6 (Hhv-6); Reactivation; Shelterin; Telomere; Viral Gene Expression

$906,525

COVID-19 Variant Supplement - Understanding the pathogenesis of COVID-19

Nominated PICIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 1

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

$50,000

Role of antibodies in platelet response to SARS-CoV-2 and its variants

Co-investigatorCIHR2021Op Grant: Emerging COVID-19 Research Gaps & Priorities - Post COVID-19 condition

Principal investigators: Boilard, Eric

Keywords: Antibodies; Inflammation; Platelets; Sars-Cov-2; Thrombosis; Variants

$261,700

Pathogenesis and immune escape potential of SARS-CoV-2 variants of concern.

Nominated PICIHR2021Operating Grant: Emerging COVID-19 Research Gaps and Priorities - Variants

Principal investigators: Flamand, Louis

Keywords: Covid-19; Immune Escape; Inflammation; Platelets; Sars-Cov-2; Serotonin; Thromboxane; Variants

$252,900

COVID-19 Variant Network - Understanding the pathogenesis of COVID-19

Nominated PICIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 2

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

$100,000

COvid-19 Vaccines Booster in Immunocompromised Rheumatic Diseases (COVBIRD).

Co-investigatorCIHR2021Op. Gr.:Emerging COVID-19 Res. Gaps & Priorities (July 2021) - Immune Responses

Principal investigators: Fortin, Paul R; De Serres, Gaston; Colmegna, Ines

Keywords: Cellular Immunity; Covid-19; Disease Flare; Humoral Immunity; Immunogenicity; Immunosuppression; Reactogenicity; Safety; Systemic Autoimmune Rheumatic Diseases; Vaccination

$995,312

Role of platelets and their mother cell, the megakaryocyte, in COVID-19

Co-investigatorCIHR2020Project Grant - Priority Announcement: Infection and Immunity

Principal investigators: Boilard, Eric

Keywords: Hemostasis; Inflammation; Megakaryocytes; Platelets; Thrombocytopenia; Thrombosis

$100,000

Understanding the pathogenesis of COVID-19

Nominated PICIHR2020Operating Grant: COVID-19 - Transmission dynamics/animal host/modeling

Principal investigators: Flamand, Louis

Keywords: Cytokines; Inflammation; Leukocytes; Lipid Mediators; Lungs; Macrophages; Novel Coronavirus; Platelets

COVID-19 trilogy: ARDS, inflammation and coagulopathy.

Nominated PICIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Flamand, Louis

Keywords: Anti-Thrombin Agents; Antibody Enhancement Of Disease; Covid-19; Cytokines; Fc Receptor; Inflammation; Lipid Mediators Of Inflammation; Pathogenesis; Platelets; Sars-Cov-2

$226,625

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Louis Flamand

Research

Latest papers

Latest funding

Engineering a Modular PapMV Nanoparticle Vaccine: Comparative Efficacy of a Covalent and a Non-Covalent N-Antigen Vaccine Against Emerging SARS-CoV-2 Variants.

Megakaryocytes Internalize and Are Activated by Immune Complexes.

Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses.

Human herpesvirus 7 and the risk of developing multiple sclerosis.

PapMV nanoparticles: A novel pathway to SARS-CoV-2 protection, distinct from Imidazoquinolines.

Thykamine&#x2122;: A New Player in the Field of Anti-Inflammatory Drugs.

Endogenous human herpesviruses 6A/B.

A Benchmark of methods for SARS-CoV-2 whole genome sequencing and development of a more sensitive method.

No Evidence of Anti-Influenza Nucleoprotein Antibodies in Retail Milk from Across Canada (April-July 2024).

Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection.

Frequent collaborators

Eric Boilard

Nicolas Flamand

Arnaud Droit

Sasha Bernatsky

Denis Leclerc

Sasha Bernatsky

Sonya MacParland

Jean-Claude Tardif

Tom Hobman

Jean-Claude Tardif

Vinod Chandran

Craig McCormick

Ines Colmegna

Steve Lacroix

Dawn Bowdish

Margaret Larche

Guy Boivin

Anne-Claude Gingras

Daniel Sinnett

Angela Brooks-Wilson

Gaston De Serres

Carol Hitchon

Denis Soulet

Nicolas Bertrand

Waliul Khan

Jean Gosselin

Thykamine™: A New Player in the Field of Anti-Inflammatory Drugs.