Faculty profile

Paul Fortin

ResearcherMedicineUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Paul Fortin

Researcher

Medicine

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
4 publications in the last five years, latest in 2026.
Principal investigator on 6 research grants (6 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Systemic Lupus Erythematosus Cellular Immunity Covid-19 Disease Flare Humoral Immunity Immunogenicity Immunosuppression Reactogenicity

Latest papers

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation.
The Journal of clinical investigation · 2026
SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naïve mice.
Communications biology · 2024
Fluctuation of Anti-Domain 1 and Anti-β2 -Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies.
Arthritis & rheumatology (Hoboken, N.J.) · 2023

All 19 publications

Latest funding

The contribution of platelets and B-cells to neurolupus pathophysiology
CIHR · 2025 · Co-investigator
$1,059,526
Role of megakaryocytes in Systemic Lupus Erythematosus
CIHR · 2022 · Co-investigator
$734,400
COvid-19 Vaccines Booster in Immunocompromised Rheumatic Diseases (COVBIRD).
CIHR · 2021 · Nominated PI
$995,312

All 12 grants and awards

19 publications.

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation.

Bellio M, Allaeys I, Doré E, Vaillancourt M, Lévesque T, Monteil M, Vallières N, Desaulniers P, Bertrand N, Washington VA, Senis Y, Lacroix S, Fortin P, Belleannée C, Boilard E

The Journal of clinical investigation2026

DOI: 10.1172/jci195987 PMID: 41329518

SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naïve mice.

Willett JDS, Gravel A, Dubuc I, Gudimard L, Dos Santos Pereira Andrade AC, Lacasse É, Fortin P, Liu JL, Cervantes JA, Galvez JH, Djambazian HHV, Zwaig M, Roy AM, Lee S, Chen SH, Ragoussis J, Flamand L

Communications biology2024

DOI: 10.1038/s42003-024-05878-3 PMID: 38365933

Fluctuation of Anti-Domain 1 and Anti-β2 -Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies.

Chighizola CB, Pregnolato F, Andrade D, Tektonidou M, Pengo V, Ruiz-Irastorza G, Belmont HM, Gerosa M, Fortin P, Branch DW, Andreoli L, Petri MA, Cervera R, Knight JS, Willis R, Efthymiou M, Cohen H, Erkan D, Bertolaccini ML, Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION)

Arthritis & rheumatology (Hoboken, N.J.)2023

DOI: 10.1002/art.42459 PMID: 36704930

A liquid chromatography-mass spectrometry assay for the quantification of nucleotide sugars in human plasma and urine specimens and its clinical application.

Caron P, Nguyen Van Long F, Rouleau M, Bujold E, Fortin P, Mohammadi S, Lévesque É, Breton S, Guillemette C

Journal of chromatography. A2022

DOI: 10.1016/j.chroma.2022.463296 PMID: 35820232

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis.

Zhao Y, Hasse S, Vaillancourt M, Zhao C, Davis L, Boilard E, Fortin P, Di Battista J, Poubelle PE, Bourgoin SG

International journal of molecular sciences2021

DOI: 10.3390/ijms222312685 PMID: 34884486

Interplay between LPA2 and LPA3 in LPA-mediated phosphatidylserine cell surface exposure and extracellular vesicles release by erythrocytes.

Hasse S, Duchez AC, Fortin P, Boilard E, Bourgoin SG

Biochemical pharmacology2021

DOI: 10.1016/j.bcp.2021.114667 PMID: 34216604

Antiphospholipid Antibody Profile Stability Over Time: Prospective Results From the APS ACTION Clinical Database and Repository.

Gkrouzman E, Sevim E, Finik J, Andrade D, Pengo V, Sciascia S, Tektonidou MG, Ugarte A, Chighizola CB, Belmont HM, Lopez-Pedrera C, Ji L, Fortin P, Efthymiou M, de Jesus GR, Branch DW, Nalli C, Petri M, Rodriguez E, Cervera R, Knight JS, Atsumi T, Willis R, Bertolaccini ML, Cohen H, Rand J, Erkan D, APS ACTION+

The Journal of rheumatology2021

DOI: 10.3899/jrheum.200513 PMID: 33259328

Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry.

Zuily S, Clerc-Urmès I, Bauman C, Andrade D, Sciascia S, Pengo V, Tektonidou MG, Ugarte A, Gerosa M, Michael Belmont H, Zamorano MAA, Fortin P, Ji L, Efthymiou M, Cohen H, Branch DW, Jesus GR, Nalli C, Petri M, Rodriguez E, Cervera R, Knight JS, Atsumi T, Willis R, Bertolaccini ML, Vega J, Wahl D, Erkan D, APS ACTION Investigators

Lupus2020

DOI: 10.1177/0961203320940776 PMID: 32703117

Construction of a Frailty Index as a Novel Health Measure in Systemic Lupus Erythematosus.

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin P, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG

The Journal of rheumatology2020

DOI: 10.3899/jrheum.181338 PMID: 30988130

Evaluating the Properties of a Frailty Index and Its Association With Mortality Risk Among Patients With Systemic Lupus Erythematosus.

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin P, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Steinsson K, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG

Arthritis & rheumatology (Hoboken, N.J.)2019

DOI: 10.1002/art.40859 PMID: 30771242

The contribution of platelets and B-cells to neurolupus pathophysiology

Co-investigatorCIHR2025Project Grant

Principal investigators: Boilard, Eric

Keywords: Antibodies; Fc Receptors; Innate B-Cells; Neurons; Platelets; Systemic Inflammation; Systemic Lupus Erythematosus

$1,059,526

Role of megakaryocytes in Systemic Lupus Erythematosus

Co-investigatorCIHR2022Project Grant

Principal investigators: Boilard, Eric

Keywords: Antibodies; Megakaryocytes; Mitochondria; Platelets; Systemic Lupus Erythematosus

$734,400

COvid-19 Vaccines Booster in Immunocompromised Rheumatic Diseases (COVBIRD).

Nominated PICIHR2021Op. Gr.:Emerging COVID-19 Res. Gaps & Priorities (July 2021) - Immune Responses

Principal investigators: Fortin, Paul R; De Serres, Gaston; Colmegna, Ines

Keywords: Cellular Immunity; Covid-19; Disease Flare; Humoral Immunity; Immunogenicity; Immunosuppression; Reactogenicity; Safety; Systemic Autoimmune Rheumatic Diseases; Vaccination

$995,312

Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis

Co-investigatorCIHR2019Project Grant

Principal investigators: Boilard, Eric

Keywords: Blood Vessels; Cytokines; Fcy Receptors; Immune Complexes; Neutrophils; Pain; Platelets; Rheumatoid Arthritis

$910,350

Canada Research Chair - Tier 1

Nominated PICIHR2018Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Fortin, Paul R

Keywords: Crc

$1,400,000

Mapping anti-mitochondrial antibodies in systemic lupus erythematosus

Nominated PICIHR2018Project Grant

Principal investigators: Fortin, Paul R

Keywords: Antibody Characterization; Arthritis; Autoimmunity; Biomarker; Mitochondria; Systemic Lupus Erythematosus

$416,280

Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis.

Co-investigatorCIHR2015Operating Grant

Principal investigators: Bourgoin, Sylvain G

Keywords: Autotaxin; Lysophosphatidic Acid; Microparticles; Platelets; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Vascular Smooth Muscle

$788,904

Dissemination of the Lupus Interactive Navigator - Measuring its uptake and impact on global health and self-care.

Nominated PICIHR2015Operating Grant: Knowledge to Action

Principal investigators: Fortin, Paul R; Da Costa, Deborah M; Haroun, Vinita

Keywords: Dissemination Strategy Of Health Information Technology; Navigation; Person-Centered Care; Randomized Trial; Systemic Lupus Erythematosus

$200,000

Role of novel microparticle subtypes derived by platelets in SLE

Co-investigatorCIHR2014Operating Grant

Principal investigators: Boilard, Eric

Keywords: Autoantigens; Immune-Complexes; In Vivo Models; Inflammation; Lupus; Microparticles; Mitochondria; Platelets

$757,624

Platelets and their microparticles: versatile players of inflammation

Co-investigatorCIHR2014Foundation Grant

Principal investigators: Boilard, Eric

Keywords: Immunity; Inflammation; Lipid Mediators; Microparticles; Phospholipase A2; Platelets; Rheumatic Diseases; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Transfusion

$1,434,894

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Paul Fortin

Research

Latest papers

Latest funding

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation.

SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-na&#xef;ve mice.

Fluctuation of Anti-Domain 1 and Anti-&#x3b2;2 -Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies.

A liquid chromatography-mass spectrometry assay for the quantification of nucleotide sugars in human plasma and urine specimens and its clinical application.

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis.

Interplay between LPA2 and LPA3 in LPA-mediated phosphatidylserine cell surface exposure and extracellular vesicles release by erythrocytes.

Antiphospholipid Antibody Profile Stability Over Time: Prospective Results From the APS ACTION Clinical Database and Repository.

Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry.

Construction of a Frailty Index as a Novel Health Measure in Systemic Lupus Erythematosus.

Evaluating the Properties of a Frailty Index and Its Association With Mortality Risk Among Patients With Systemic Lupus Erythematosus.

Frequent collaborators

Sasha Bernatsky

Sasha Bernatsky

Eric Boilard

Kenneth Rockwood

Kara Thompson

Pantelis Andreou

Christine Peschken

Susan Kirkland

Marie Hudson

Janet Pope

Linda Kwakkenbos

Paul Fortin

Kenneth Rockwood

Sylvie Breton

Evelyne Vinet

Carol Hitchon

Nicolas Bertrand

Sasha Bernatsky

Arielle Mendel

Steve Lacroix

Arielle Mendel

Evelyne Vinet

Nicole Anderson

Nader Khalidi

Murray Baron

Louis Flamand

Margaret Larche

SARS-CoV-2 rapidly evolves lineage-specific phenotypic differences when passaged repeatedly in immune-naïve mice.

Fluctuation of Anti-Domain 1 and Anti-β2 -Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies.