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Research
Latest papers
Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.
Carcinogenesis · 2025
Protein-altering germline mutations implicate novel genes related to lung cancer development.
Nature communications · 2020
Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse.
Molecular genetics & genomic medicine · 2018 · senior author
Latest funding
- $868,275
Circulating Anti-TREK-1 Autoantibodies as Diagnostic and Prognostic Biomarkers in Short-Coupled Ventricular Fibrillation
CIHR · 2026 · Co-investigator
- $1,189,576
The lung molecular and cellular transition to adenocarcinoma
CIHR · 2025 · Nominated PI
- $757,352
Identification of specific proteomic and genomic biomarkers for calcific aortic valve stenosis and its progression
CIHR · 2024 · Co-investigator
5 publications.
Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.
Dong M, Thakral A, Byrne KS, Bosse Y, Zhou H, Zhang Y, Atkins J, Haycock P, Brown MC, Murison K, Timens W, Sin DD, Kothari J, Gabriel AAG, Zaridze D, Savic M, Lissowska J, Świątkowska B, Janout V, Holcatova I, Mukeria A, Fernandez-Tardon G, Davies MPA, Triplette M, Schabath MB, Andrew AS, Chen C, Taylor F, Field JK, Tardon A, Shete SS, Brennan P, Landi MT, McKay J, Amos CI, Lin X, Christiani DC, Hung RJ, Liu G, Xu W
Protein-altering germline mutations implicate novel genes related to lung cancer development.
Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Byun J, Dragnev KH, Field JK, Kiemeney LF, Lazarus P, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Diao N, Su L, Song L, Zhang R, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, Heijden EHFMV, Kim JH, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Goodman GE, Cox A, Taylor F, Woll P, Wichmann E, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Butler LM, Offit K, Srinivasan P, Bandlamudi C, Hellmann MD, Solit DB, Robson ME, Rudin CM, Stadler ZK, Taylor BS, Berger MF, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Artigas MS, Shete S, Brenner H, Chanock S, Brennan P, McKay JD, Amos CI
Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse.
Clemenceau A, Bérubé JC, Bélanger P, Gaudreault N, Lamontagne M, Toubal O, Clavel MA, Capoulade R, Mathieu P, Pibarot P, Bosse Y
Genetic association analyses highlight biological pathways underlying mitral valve prolapse.
Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, PROMESA investigators, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, MVP-France, Jeunemaitre X, Leducq Transatlantic MITRAL Network
Inflammation is associated with the remodeling of calcific aortic valve disease.
Coté N, Mahmut A, Bosse Y, Couture C, Pagé S, Trahan S, Boulanger MC, Fournier D, Pibarot P, Mathieu P
Circulating Anti-TREK-1 Autoantibodies as Diagnostic and Prognostic Biomarkers in Short-Coupled Ventricular Fibrillation
Principal investigators: Steinberg, Christian
Keywords: Anti-Trek-1; Autoimmune; Cardiac Electrophysiology; Channelopathy; Idiopathic Ventricular Fibrillation; Primary Electrical Disorder; Short-Coupled Ventricular Fibrillation
The lung molecular and cellular transition to adenocarcinoma
Principal investigators: Bossé, Yohan
Keywords: Bioinformatics; Causal Genes; Expression Quantitative Trait Loci; Genomics; Genotyping; Lung Cancer; Lung Tissue; Ngs Panel; Single-Cell Analysis; Twas
Identification of specific proteomic and genomic biomarkers for calcific aortic valve stenosis and its progression
Principal investigators: Thériault, Sébastien
Keywords: Aortic Valve Stenosis; Biomarkers; Polygenic Risk Scores; Prediction Models; Prognosis; Proteomics
The lung molecular and cellular transition to adenocarcinoma
Principal investigators: Bossé, Yohan
Keywords: Bioinformatics; Causal Genes; Expression Quantitative Trait Loci; Genomics; Genotyping; Lung Cancer; Lung Tissue; Ngs Panel; Single-Cell Analysis; Twas
Molecular and Genetic Epidemiology to Understand Mitral Valve Prolapse
Principal investigators: Mathieu, Patrick
Keywords: Biomarkers; Gene Expression; Mitral Valve Prolapse; Molecular And Genetic Epidemiology; Proteome
Sex and sex-hormones determine pulmonary morphological and single-nucleus transcriptomic responses in an animal model of sleep apnea.
Principal investigators: Joseph, Vincent
Keywords: Intermittent Hypoxia; Lung Morphology; Male And Female Mice; Ovariectomy - Orchiectomy; Single Cell/Nucleus Rna Sequencing; Sleep Apnea
A transcriptome- and proteome-wide association study of non-alcoholic fatty liver disease
Principal investigators: Arsenault, Benoit
Keywords: Electronic Health Records; Genetic Variation; Liver Histopathology; Mendelian Randomization; Non-Alcoholic Fatty Liver Disease; Proteomics; Single-Nucleotide Polymorphisms; Transcriptomics
Elucidating the role of lipoprotein(a) in calcific aortic valve stenosis using novel proteomic and imaging approaches
Principal investigators: Arsenault, Benoit
Keywords: Aortic Valve Calcification; Calcific Aortic Valve Stenosis; Family Study; Genetics; Inflammation; Lipidomics; Lipoprotein(A); Positron Emission Tomography/Computed Tomography; Proteomics; Transcriptomics
Canada Research Chair - Tier 2
Principal investigators: Bossé, Yohan
Keywords: Crc
Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema
Principal investigators: Morissette, Mathieu
Keywords: Clinical Samples; Emphysema; Immunology; Mouse Model; Ptpn6; Smoking
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Molecular Medicine
- Epidemiology Division
- Medicine
- Department of Laboratory Medicine and Pathobiology
- Surgery
- Biostatistics Division
- Other
Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Geoffrey Liu
Epidemiology Division
2 shared papers, latest 2025
Mark Lathrop
Faculty
1 shared papers, latest 2015
Patrick Mathieu
Surgery
1 shared papers, latest 2013
Ming-Sound Tsao
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2020
Stephen Lam
Faculty
1 shared papers, latest 2020
Wei Xu
Biostatistics Division
1 shared papers, latest 2025
Ma'en Obeidat
Medicine
1 shared papers, latest 2020
Philippe Joubert
Faculty
1 shared papers, latest 2020
Kiera Murison
Faculty
1 shared papers, latest 2025
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