Faculty profile

Ming-Sound Tsao

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ProfessorDepartment of Laboratory Medicine and PathobiologyUniversity of Toronto

Ming-Sound Tsao

Professor

Department of Laboratory Medicine and Pathobiology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Scholar ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
63 publications in the last five years, latest in 2026.
Senior (last) author on 14 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2025.
Supervised 8 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

320

Publications

5,056

Citations

h-index

144

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Education

MD
B.SC. (Hons)

Profiles and links

University Profile Personal Website Google Scholar iDORCID

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Targeted Therapy Non-Small Cell Lung Cancer Lung Cancer M6a Rna Modification Crispr-Cas9 Drug Resistance Drug Tolerant Persister Egfr Tyrosine Kinase Inhibitor

Latest papers

SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies.
iScience · 2026
Prognostic Significance of Spread Through Airspaces (STAS) in Stage Ia/bN0 Non-small Cell Lung Cancer - An Evaluation in the JCOG0802/WJOG4607L Clinical Trial Patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026 · senior author
Machine Learning Assessment of Pathologic Response in Lung Cancer Resections After Neoadjuvant Therapy-IASLC MPR Project.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026

All 320 publications

Latest funding

Leveraging oncolytic viruses to realize the therapeutic potential of CD47 blockade in lung cancer
CIHR · 2026 · Co-investigator
$1,097,776
Liquid-biopsy profiling of EZH2-driven H3K27me3 remodeling to overcome treatment resistance in small-cell lung cancer
CIHR · 2026 · Co-investigator
$1,109,250
The N6-methyladenosine Epitranscriptome and Functional Landscape of Lung Adenocarcinoma
CIHR · 2025 · Principal investigator
$1,147,500

All 40 grants and awards

From the 150 most recent of 320 publications.

SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies.

Wu BX, Ran X, Huang O, Song L, Philip V, Sacher A, Tsao MS, Lok BH

iScience2026

DOI: 10.1016/j.isci.2026.116864 PMID: 42548914

Prognostic Significance of Spread Through Airspaces (STAS) in Stage Ia/bN0 Non-small Cell Lung Cancer - An Evaluation in the JCOG0802/WJOG4607L Clinical Trial Patients.

Yatabe Y, Beasley MB, Borczuk A, Berezowska S, Bubendorf L, Chang WC, Chou TY, Cooper WA, Dacic S, Han Y, Hayashi T, Hofman P, Hwang DM, Jain D, Joubert P, Kerr K, Kim TJ, Kishikawa S, Le Quesne J, Lin D, Lopez-Rios F, Minami Y, Mino-Kenudson M, Mitome N, Nicholson AG, Papotti M, Roden AC, Saji H, Saqi A, Shim HS, Fernandes Tavora FR, von der Thüsen J, Yoshizawa A, Wakabayashi M, Watanabe SI, Asamura H, Tsao MS

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2026Senior author

DOI: 10.1016/j.jtho.2026.104156 PMID: 42600842

Machine Learning Assessment of Pathologic Response in Lung Cancer Resections After Neoadjuvant Therapy-IASLC MPR Project.

Dacic S, Shenker D, Redman M, Brunner L, Saqi A, Cooper WA, Borczuk A, Chung JH, Glass C, Lopez JM, Roden AC, Sholl L, Weissferdt A, Brosnan-Cashman J, Hennek S, Grullon S, Posadas J, Fujimoto J, Connolly C, Wynes MW, Sanchez-Espiridion B, Lee JJ, Berezowska S, Chou TY, Kerr K, Nicholson AG, Schalper KA, Tsao MS, Ready N, Cascone T, Heymach J, Sepesi B, Shu C, Rizvi N, Sonett J, Altorki N, Provencio M, Bunn PA, Kris MG, Travis W, Yu L, Wistuba I, IASLC Pathology Committee

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2026

DOI: 10.1016/j.jtho.2026.103953 PMID: 42229633

Identifying Patients With High-Risk Stage I NSCLC Using a Tumor-Informed Plasma ctDNA Assay.

Feng J, Khan S, Waddell TK, Yasufuku K, Coyne Z, Kelly D, Meti N, Safieddine N, Ko M, Pierre A, Keshavjee S, Wakeam E, Donahoe L, Cypel M, Yeung J, de Perrot M, Ahmadi N, Gazala S, Simone C, Parente D, Rabey MR, Law JH, Li JJN, Salvarrey A, Le LW, Seto A, Cabanero M, Tsao MS, Pipinikas C, Chevalier A, Bratman SV, Leighl NB

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2026

DOI: 10.1016/j.jtho.2026.103645 PMID: 41730473

Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms.

Rosen JC, Cao P, Pham NA, Waas M, Li Q, Hueniken K, Wang M, Navab R, Wybenga-Groot L, Radulovich N, Niedbala M, Koers A, Ross S, Moran MF, Sacher A, Tsao MS

British journal of cancer2026Senior author

DOI: 10.1038/s41416-025-03216-w PMID: 41076489

Integration of Histologic Pattern Classifiers and Graph Convolutional Networks for Prognostic Prediction in Lung Adenocarcinoma.

Yeh YC, Yu WH, Hsieh MS, Chang FP, Wang LC, Lu CW, Karlaš B, Yu KH, Wu YC, Chen JS, Tsao MS, Yeh CY, Chou TY

JTO clinical and research reports2026

DOI: 10.1016/j.jtocrr.2026.101017 PMID: 42703598

Endobronchial Ultrasound-Guided Biopsy-Derived Lung Cancer Models: A Platform for Precision Therapy.

Koga T, Ogawa H, Radulovich N, Pham NA, Li Q, Nakajima T, Djan M, Li M, Wang Y, Hinokuma H, Fujibayashi Y, Hiraishi Y, Sata Y, Kitazawa S, Suzuki M, Aoi T, Maniwa Y, Tsao MS, Yasufuku K

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2026

DOI: 10.1016/j.jtho.2026.103893 PMID: 42055160

Preclinical Combination Targeting VEGF and PI3K in a Rare, Aggressive Mixed Endometrial Carcinoma: An Applied Case Report.

Radulovich N, Pina PS, Udaskin ML, Li Q, Nixon KCJ, Xie IY, Nand A, Rosen JC, Li M, Hodgson A, Pham NA, Oza AM, Lupien M, Rottapel R, Tsao MS, Lheureux S

Cancer research communications2026

DOI: 10.1158/2767-9764.crc-25-0634 PMID: 41886729

mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion.

Gentile C, Feng WW, Lenahan SM, Ying AW, Card DC, Wu FTH, Pham NA, Radulovich N, Cao PM, Hueniken K, Li Q, Tsao MS, Kulesza J, Hinkley MM, Liao L, Tsai JA, Köhler J, Facchinetti F, Li J, Weston C, Locquet MA, Ngo K, Gokhale PC, Sacher AG, Jänne PA, Kadoch C

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.02.27.708377 PMID: 42124568

METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers.

Xu X, Wang Y, Zhu H, Lam M, Luo W, Teng M, Liu Y, Guo WY, Aastha A, Xu X, Chen S, Ci X, Wang S, Zeng Y, Zhu G, Kislinger T, Lupien M, Tsao MS, He HH

Nature cancer2026

DOI: 10.1038/s43018-026-01117-2 PMID: 41652220

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Ming-Sound Tsao

Research

Latest papers

Latest funding

SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies.

Prognostic Significance of Spread Through Airspaces (STAS) in Stage Ia/bN0 Non-small Cell Lung Cancer - An Evaluation in the JCOG0802/WJOG4607L Clinical Trial Patients.

Machine Learning Assessment of Pathologic Response in Lung Cancer Resections After Neoadjuvant Therapy-IASLC MPR Project.

Identifying Patients With High-Risk Stage I NSCLC Using a Tumor-Informed Plasma ctDNA Assay.

Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms.

Integration of Histologic Pattern Classifiers and Graph Convolutional Networks for Prognostic Prediction in Lung Adenocarcinoma.

Endobronchial Ultrasound-Guided Biopsy-Derived Lung Cancer Models: A Platform for Precision Therapy.

Preclinical Combination Targeting VEGF and PI3K in a Rare, Aggressive Mixed Endometrial Carcinoma: An Applied Case Report.

mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion.

METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers.

Frequent collaborators

Geoffrey Liu

Stephen Lam

Kazuhiro Yasufuku

Igor Jurisica

Lesley Seymour

Adrian Sacher

Nadeem Moghal

John Goffin

Jean-claude Cutz

Jenna Sykes

Wei Xu

Li Zhang

Paul Wheatley-Price

Mitsuhiko Ikura

Rosalyn Juergens

Lisa Wang

Gregory Pond

Serge Puksa

Steven Gallinger

Benjamin Haibe-Kains

Sebastien Hotte

Shaf Keshavjee

Thomas Kislinger

David Hwang

Philippe Joubert

Sonya Cressman

Kayvan Amjadi

Tracy Stockley

Lori Stewart

David Hedley

Mathieu Lupien

Virginijus Barzda

Glenwood Goss

Ma'en Obeidat

Robert Rottapel

Peter Ellis

Scott Tsai

William Evans

Aly Karsan

Stephen Welch