Faculty profile
Daniel Zenklusen
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Research
Latest papers
Mechanisms of Messenger RNA Packaging and Export.
Annual review of cell and developmental biology · 2025
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Immunity · 2024
Differential affinity purification and mass spectrometry analysis of two nuclear pore complex isoforms in yeast S. cerevisiae.
STAR protocols · 2023
Latest funding
- $100,000
Investigate features and dynamics of intron RNP biology and its role in modulating RNA metabolism
CIHR · 2023 · Nominated PI
- $914,175
Investigate features and dynamics of intron RNP topology and its role in modulating RNA metabolism
CIHR · 2023 · Nominated PI
- $10,000
Nuclear Transport Meeting 2022
CIHR · 2022 · Nominated PI
13 publications.
Mechanisms of Messenger RNA Packaging and Export.
Faraway R, Zenklusen D, Plaschka C
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Sun S, You E, Hong J, Hoyos D, Del Priore I, Tsanov KM, Mattagajasingh O, Di Gioacchino A, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Hozeifi S, Rosas-Bringas O, Xu KH, Song Y, Lang ER, Rojas AS, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD
Differential affinity purification and mass spectrometry analysis of two nuclear pore complex isoforms in yeast S. cerevisiae.
Bensidoun P, Zenklusen D, Oeffinger M
Nuclear mRNA metabolism drives selective basket assembly on a subset of nuclear pore complexes in budding yeast.
Bensidoun P, Reiter T, Montpetit B, Zenklusen D, Oeffinger M
Probing the Conformational State of mRNPs Using smFISH and SIM.
Adivarahan S, Zenklusen D
Lessons from (pre-)mRNA Imaging.
Adivarahan S, Zenklusen D
Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway.
Adivarahan S, Livingston N, Nicholson B, Rahman S, Wu B, Rissland OS, Zenklusen D
Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway.
Lessard F, Igelmann S, Trahan C, Huot G, Saint-Germain E, Mignacca L, Del Toro N, Lopes-Paciencia S, Le Calvé B, Montero M, Deschênes-Simard X, Bury M, Moiseeva O, Rowell MC, Zorca CE, Zenklusen D, Brakier-Gingras L, Bourdeau V, Oeffinger M, Ferbeyre G
Imaging single mRNAs to study dynamics of mRNA export in the yeast Saccharomyces cerevisiae.
Bensidoun P, Raymond P, Oeffinger M, Zenklusen D
The nuclear basket mediates perinuclear mRNA scanning in budding yeast.
Saroufim MA, Bensidoun P, Raymond P, Rahman S, Krause MR, Oeffinger M, Zenklusen D
Investigate features and dynamics of intron RNP biology and its role in modulating RNA metabolism
Principal investigators: Zenklusen, Daniel R
Keywords: Innate Immune Response; Introns; Nuclear Organization; Rna; Rna-Binding Proteins; Rnp Topology; Single-Molecule Microscopy; Splicing; Super-Resolution Microscopy
Investigate features and dynamics of intron RNP topology and its role in modulating RNA metabolism
Principal investigators: Zenklusen, Daniel R
Keywords: Innate Immune Response; Introns; Nuclear Organization; Rna; Rna Degradation; Rna-Binding Proteins; Rnp Topology; Single-Molecule Microscopy; Splicing; Super-Resolution Microscopy
Nuclear Transport Meeting 2022
Principal investigators: Zenklusen, Daniel R
Keywords: Meeting; Nuclear Transport
Deciphering the role of nuclear organization in mRNA and lncRNA nuclear retention
Principal investigators: Zenklusen, Daniel
Drop-based microfluidics (DBM) for single cell studies and ultrahigh-throughput phenotypic screens and lab evolution
Principal investigators: Serohijos, Adrian
Determining the role of the nuclear basket protein Mlp1/TPR in mRNA homeostasis
Principal investigators: Zenklusen, Daniel R
Keywords: Functional Specialization; Gene Expression; Mrna Export; Nuclear Basket; Nuclear Pore Complex; Phase Separation; Proteomics; Single Molecule Resolution Microscopy; Super-Resolution Microscopy
Investigate The Role Of mRNP Structure In Translation And RNA Metabolism
Principal investigators: Zenklusen, Daniel R
Keywords: Biophysics; Cancer; Gene Expression Regulation; Rapamycin; Rna Binding Proteins; Rna Conformation; Rna Strucutre; Single Molecule Resolution Microscopy; Superresolution Micorscopy; Translation Regulation
Determining the pathways, components and functional niches that define specialized ribosomes.
Principal investigators: Oeffinger, Marlene H
Keywords: Affinity Chromatography; Biochemistry; Bioinformatics; Molecular Biology; Proteomics; Ribonucleoprotein Maturation Pathways; Ribosome; Ribosomopathies; Rna; Translation Control
Dissecting the role of the nuclear basket in regulating mRNA metabolism
Principal investigators: Zenklusen, Daniel
A molecular imager for Quantitative biochemistry
Principal investigators: Legault, Pascale
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Gerardo Ferbeyre and Gerardo Ferbeyre: 43 shared papers
- Daniel Zenklusen and Marlene Oeffinger: 2 shared papers
- Gerardo Ferbeyre and Daniel Zenklusen: 1 shared paper
- Gerardo Ferbeyre and Marlene Oeffinger: 1 shared paper
- Daniel Zenklusen and Gerardo Ferbeyre: 1 shared paper
- Marlene Oeffinger and Gerardo Ferbeyre: 1 shared paper
- Biochimie et médecine moléculaire
- Systems Biology
- Microbiology
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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