Faculty profile

Gerardo Ferbeyre

ResearcherBiochimie et médecine moléculaireUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Gerardo Ferbeyre

Researcher

Biochimie et médecine moléculaire

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
15 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 16 research grants (10 CIHR, 6 NSERC), most recently in 2025.
Supervised 4 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Senescence Pancreatic Cancer Inflammation Tumor Suppression Ribosome Biogenesis Cellular Senescence Senolytics Epigenetics

Latest papers

Clearance of p16-positive cardiac cells improves age-related cardiac remodeling in mice.
Experimental physiology · 2026
Development and validation of HPLC-UV and HPLC-MS/MS methods for ML-210 quantification.
Talanta · 2026
The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.
eLife · 2026 · senior author

All 43 publications

Latest funding

Design of cis-regulatory elements active in hybrid and transitory states along developmental transitions
CIHR · 2025 · Co-investigator
$983,025
RUNX1 and ETV4: Gatekeepers of Senescence and Epigenetic Rewiring for Cancer Therapy
CIHR · 2025 · Supervisor
$1,500
Role of the noncoding chromatin in cellular senescence
CIHR · 2025 · Nominated PI
$1,028,925

All 30 grants and awards

43 publications.

Clearance of p16-positive cardiac cells improves age-related cardiac remodeling in mice.

Mehdizadeh M, Mackasey M, Gharagozloo K, Aguilar M, Naud P, Ochs A, Vuong-Robillard N, Thorin E, Ferbeyre G, Tardif JC, Sirois MG, Tanguay JF, Nattel S

Experimental physiology2026

DOI: 10.1113/ep093551 PMID: 42734482

Development and validation of HPLC-UV and HPLC-MS/MS methods for ML-210 quantification.

Murphy M, Mahrouche L, Jutras M, Friciu M, Rodier F, Ferbeyre G, Yu F, Roullin VG, Leclair G

Talanta2026

DOI: 10.1016/j.talanta.2026.130422 PMID: 42594441

The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

Lefrançois G, Lavallée E, Rowell MC, Bourdeau V, Mohebali F, Bertomeu T, Duman AM, Nikolova M, Tyers M, Gravel SP, Schmitzer AR, Ferbeyre G

eLife2026Senior author

DOI: 10.7554/elife.102680 PMID: 42138716

STAT1/3/5 Functions Driving Lipid and Energy Metabolism in Cancer and Immunity.

Rinnerthaler M, Sykora M, Christoforakos A, Aberger F, Ferbeyre G, Moriggl R

International journal of molecular sciences2026

DOI: 10.3390/ijms27062828 PMID: 41898687

Precision targeting of the SASP in cancer therapy.

Hassan S, Ferbeyre G

Nature aging2026Senior author

DOI: 10.1038/s43587-025-01052-4 PMID: 41634463

A one-two punch against cancer: combining CDK4 inhibitors with lysosomotropic agents.

Ferbeyre G

The EMBO journal2025First author

DOI: 10.1038/s44318-025-00396-2 PMID: 39994486

The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology.

Mehdizadeh M, Naud P, Abu-Taha IH, Hiram R, Xiong F, Xiao J, Saljic A, Kamler M, Vuong-Robillard N, Thorin E, Ferbeyre G, Tardif JC, Sirois MG, Tanguay JF, Dobrev D, Nattel S

Cardiovascular research2024

DOI: 10.1093/cvr/cvae003 PMID: 38181429

A senescence restriction point acting on chromatin integrates oncogenic signals.

Lopes-Paciencia S, Bourdeau V, Rowell MC, Amirimehr D, Guillon J, Kalegari P, Barua A, Quoc-Huy Trinh V, Azzi F, Turcotte S, Serohijos A, Ferbeyre G

Cell reports2024Senior author

DOI: 10.1016/j.celrep.2024.114044 PMID: 38568812

Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates.

Deschênes-Simard X, Malleshaiah M, Ferbeyre G

Cancers2023Senior author

DOI: 10.3390/cancers16010095 PMID: 38201521

SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation.

Khan MGM, Boufaied N, Yeganeh M, Kandhi R, Petkiewicz S, Sharma A, Yoshimura A, Ferbeyre G, Labbé DP, Ramanathan S, Ilangumaran S

Cancers2023

DOI: 10.3390/cancers15030905 PMID: 36765862

Design of cis-regulatory elements active in hybrid and transitory states along developmental transitions

Co-investigatorCIHR2025Project Grant

Principal investigators: Lalanne, Jean-Benoit

Keywords: Differentiation Trajectories; Epithelial-To-Mesenchymal Transition; Functional & Regulatory Genomics; Gene Expression Control; Predictive Mathematical Modeling; Quantitative Multiplex Reporters; Sequence-To- Function Maps; Single-Cell Assays; Synthetic Dna Sensors; Transcriptional Cis-Regulatory Elements/Enhancers

$983,025

RUNX1 and ETV4: Gatekeepers of Senescence and Epigenetic Rewiring for Cancer Therapy

SupervisorCIHR2025Travel Awards - Institute Community Support

Principal investigators: Menggad, Saad

Keywords: Biochemistry; Cell Cycle Arrest (P15, P16 & P21); Chromatin Remodeling (Ezh2, Prc2 & Hdac4); Epigenetic Modifications; Molecular Biology; Oncogene-Induced Senescence; Pancreatic Cancers; Pharmacological Anti-Cancer Treatment; Proliferation And Proliferation Arrest; Transcription Factors (Runx1 & Etv4)

$1,500

Role of the noncoding chromatin in cellular senescence

Nominated PICIHR2025Project Grant

Principal investigators: Ferbeyre, Gerardo

Keywords: Epigenetics; Noncoding Dna; Pancreatic Cancer; Senescence; Transcription Factors; Tumor Suppression

$1,028,925

Unveiling the Role of Cellular Aging in Postmenopausal Syndrome: Rationale for Senolytic-Based Strategies to Enhance Women's Health

Co-investigatorCIHR2023Catalyst Grant: NWHRI: Innovation Fund - Biomedical Discovery Grants

Principal investigators: Mes-Masson, Anne-Marie

Keywords: Estrogen Deprivation; Menopause; New Therapeutic Strategies; Senescence; Women'S Health

$108,000

Senolytic therapy for Menopause Induced Senescent Cells, the pathological mediators of estrogen deprivation.

SupervisorCIHR2023Fellowship - Priority Announcement: Aging

Principal investigators: Vuong, Nhung H

Keywords: Menopause; Metastasis; Ovarian Cancer; Ovariectomy; Senescence

$135,000

CIACCO-2024 (11th Annual symposium on Cytokines in Inflammation, Ageing, CanCer and Obesity)

Principal investigatorCIHR2023Planning and Dissemination Grant - Institute Community Support

Principal investigators: Rafei, Moutih; Del Rincon, Sonia V; Ferbeyre, Gerardo; Fritz, Jorg H; Ilangumaran, Subburaj; Lee, Seung-Hwan; Menendez, Alfredo; Rangachari, Manu; Saucier, Caroline

Keywords: Ageing; Basic Research; Cancer; Cytokines; Immune Response; Infectious Diseases; Inflammation; Novel Therapies; Obesity; Translational Medicine

$10,000

Inflammatory phenotype, senescence, and viscoelasticity imaging of macrophages in HIV

Co-investigatorCIHR2023Project Grant

Principal investigators: Cloutier, Guy

Keywords: Acoustic Shear Wave Analysis; Cell Elasticity; Cell Viscosity; Early Atherosclerosis; Imaging Of Cell Biomechanics; Immune System Senescence; Macrophage Engulfing; Macrophages; People Living With Hiv; Premature Aging

$726,750

Characterization of lincRNA-miRNA networks

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Ferbeyre, Gerardo

Keywords: Argonautes; cell biology; cellular senescence; CRISPR; cytokines; immunofluorescence imaging; lincRNA; miR-146; miR-Clip; miRNAs

$80,000

Elimination of senescent cells to treat estrogen-deprivation associated disorders

Nominated PICIHR2022Project Grant

Principal investigators: Ferbeyre, Gerardo

Keywords: Cellular Senescence; Estrogens; Inflammation; Macrophages; Menopause; Micrornas; Senolytics

$956,250

Targeting ribosomal RNA biogenesis to restore the senescence tumor suppression mechanism

Nominated PICIHR2022Project Grant

Principal investigators: Ferbeyre, Gerardo

Keywords: Cellular Senescence; Ferroptosis; Folfirinox; Mouse Model; Pancreatic Cancer; Patient Derived Organoids; Ribosome Biogenesis; Senolytics

$879,750

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Gerardo Ferbeyre

Research

Latest papers

Latest funding

Clearance of p16-positive cardiac cells improves age-related cardiac remodeling in mice.

Development and validation of HPLC-UV and HPLC-MS/MS methods for ML-210 quantification.

The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

STAT1/3/5 Functions Driving Lipid and Energy Metabolism in Cancer and Immunity.

Precision targeting of the SASP in cancer therapy.

A one-two punch against cancer: combining CDK4 inhibitors with lysosomotropic agents.

The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology.

A senescence restriction point acting on chromatin integrates oncogenic signals.

Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates.

SOCS1 Deficiency Promotes Hepatocellular Carcinoma via SOCS3-Dependent CDKN1A Induction and NRF2 Activation.

Characterization of lincRNA-miRNA networks

Frequent collaborators

Gerardo Ferbeyre

Eric Thorin

Eric Thorin

Stanley Nattel

Subburaj Ilangumaran

Mohan Malleshaiah

Sheela Ramanathan

Volker Blank

Jean-Claude Tardif

Jean-Claude Tardif

Adel Schwertani

Marlene Oeffinger

Julie Fradette

Michael Pollak

Ivan Topisirovic

Pierrette Gaudreau

Wassim Kassouf

Francis Rodier

Subburaj Ilangumaran

Simon-Pierre Gravel

Pierre Thibault

Jan Seuntjens

Marek Rola-Pleszczynski

Pascal Chartrand

Marie-France Langlois

Pierrette Gaudreau