Faculty profile

Denis-Claude Roy

ResearcherUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Denis-Claude Roy

Researcher

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2026.
Principal investigator on 6 research grants (4 CIHR, 2 NSERC), most recently in 2020.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Co-Culture,Cytokine Secretion Cytotoxic Assay Minor Histocompatibility Antigens (Miha)Next Generation Sequencing Personalized Cancer Immunotherapy,T Cell Receptor (Tcr)T Cells

Latest papers

Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders.
Open forum infectious diseases · 2026
The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells.
Communications biology · 2025
Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge.
Transplantation and cellular therapy · 2023

All 33 publications

Latest funding

Exploiting minor histocompatibility antigens for personalized cancer immunotherapy
CIHR · 2020 · Nominated PI
$1,067,175
CellCAN Regenerative Medicine and Cell Therapy Network
CIHR · 2017 · Nominated PI
$300,000
Elucidating mechanisms of MSC-induced tissue regeneration: path to mesenchymal stromal cell clinical trial in glaucoma
CIHR · 2015 · Nominated PI
$596,450

All 9 grants and awards

33 publications.

Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders.

Schweitzer L, Thiant S, Thérien C, Giroux M, Lachance S, Fleury I, Orio J, Carli C, Boudreau G, Patenaude J, Tremblay-Laganière C, Senécal L, Dufresne SF, Mollica L, Collette S, Sauvageau G, Kiss T, Cohen S, Bernard L, Bambace N, Veilleux O, Ahmad I, Roy J, Busque L, Duval M, Bittencourt H, Teira P, Lamarche C, Roy DC, Delisle JS

Open forum infectious diseases2026

DOI: 10.1093/ofid/ofag006 PMID: 41614086

The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells.

Tu TH, Bennani FE, Masroori N, Liu C, Nemati A, Rozza N, Grunbaum AM, Kremer R, Milhalcioiu C, Roy DC, Rudd CE

Communications biology2025

DOI: 10.1038/s42003-024-07350-8 PMID: 39762551

Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge.

Lachance S, Bourguignon A, Boisjoly JA, Bouchard P, Ahmad I, Bambace N, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Veilleux O, Zehr J, Chagnon M, Roy J

Transplantation and cellular therapy2023

DOI: 10.1016/j.jtct.2022.10.003 PMID: 36243319

Two types of human TCR differentially regulate reactivity to self and non-self antigens.

Trofimov A, Brouillard P, Larouche JD, Séguin J, Laverdure JP, Brasey A, Ehx G, Roy DC, Busque L, Lachance S, Lemieux S, Perreault C

iScience2022

DOI: 10.1016/j.isci.2022.104968 PMID: 36111255

Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome.

Kadri Y, Phan M, Bambace N, Bernard L, Cohen S, Delisle JS, Kiss T, Lachance S, Roy DC, Sauvageau G, Veilleux O, Roy J, Ahmad I

Current oncology (Toronto, Ont.)2022

DOI: 10.3390/curroncol29080470 PMID: 36005208

Negative Regulation of Zap70 by Lck Forms the Mechanistic Basis of Differential Expression in CD4 and CD8 T Cells.

Damen H, Tebid C, Viens M, Roy DC, Dave VP

Frontiers in immunology2022

DOI: 10.3389/fimmu.2022.935367 PMID: 35860252

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.

Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, Lemieux S, Perreault C, Rodier F, Dufresne SF, Busque L, Lachance S, Sauvageau G, Cohen S, Delisle JS

Transplantation and cellular therapy2021

DOI: 10.1016/j.bbmt.2020.09.031 PMID: 33022376

Stigma associated with parental depression or cancer: Impact on spouse and offspring's cortisol levels and socioemotional functioning.

Lupien SJ, Roy DC, Raymond C, Leclaire S, Wan N, Labelle R, Giguère CÉ, Ouellet-Morin I

Development and psychopathology2020

DOI: 10.1017/s0954579420001431 PMID: 33427165

Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags.

Bastien JP, Fekete N, Beland AV, Lachambre MP, Laforte V, Juncker D, Dave V, Roy DC, Hoesli CA

Journal of translational medicine2020

DOI: 10.1186/s12967-020-02543-1 PMID: 33036618

Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions.

Silvestri G, Trotta R, Stramucci L, Ellis JJ, Harb JG, Neviani P, Wang S, Eisfeld AK, Walker CJ, Zhang B, Srutova K, Gambacorti-Passerini C, Pineda G, Jamieson CHM, Stagno F, Vigneri P, Nteliopoulos G, May PC, Reid AG, Garzon R, Roy DC, Moutuou MM, Guimond M, Hokland P, Deininger MW, Fitzgerald G, Harman C, Dazzi F, Milojkovic D, Apperley JF, Marcucci G, Qi J, Polakova KM, Zou Y, Fan X, Baer MR, Calabretta B, Perrotti D

Blood cancer discovery2020

DOI: 10.1158/0008-5472.bcd-19-0039 PMID: 32974613

Exploiting minor histocompatibility antigens for personalized cancer immunotherapy

Nominated PICIHR2020Project Grant

Principal investigators: Roy, Denis-Claude

Keywords: Co-Culture,; Cytokine Secretion; Cytotoxic Assay; Minor Histocompatibility Antigens (Miha); Next Generation Sequencing; Personalized Cancer Immunotherapy,; T Cell Receptor (Tcr); T Cells

$1,067,175

CellCAN Regenerative Medicine and Cell Therapy Network

Nominated PICIHR2017NCE Knowledge Mobilization Initiative

Principal investigators: Roy, Denis-Claude

Keywords: Cell Therapy; Cellcan; Transplatation

$300,000

Elucidating mechanisms of MSC-induced tissue regeneration: path to mesenchymal stromal cell clinical trial in glaucoma

Nominated PICIHR2015Operating Grant

Principal investigators: Roy, Denis-Claude

Keywords: Cellular Therapy; Glaucoma; Mesenchymal Stem Cells

$596,450

Clinical application of a novel molecule that expands human cord blood stem cells

Co-investigatorCIHR2014Operating Grant

Principal investigators: Roy, Jean; Cohen, Sandra; Sauvageau, Guy

Keywords: Cord Blood Transplantation; Fed Batch Culture System; Hematopoietic Stem Cell Expansion; Novel Agonist Of Stem Cell Renewal; Phase I Clinical Study

$1,013,167

KM - CellCAN RCTN - Regenerative Cell Therapy Network

Principal investigatorNSERC2013Networks of Centres of Excellence

Principal investigators: Roy, DenisClaude

$449,686

Personalized Cancer Immunotherapy

Co-investigatorCIHR2012Genomics and Personalized Health

Principal investigators: Perreault, Claude

Keywords: Cellular Therapy; Clinical Trials; Hematologic Cancers Immunotherapy; Immunogenetics; T-Cell Biology

$2,499,770

RCTN - Regenerative Cell Therapy Network / Réseau de thérapie cellulaire régénérative

Principal investigatorNSERC2012Networks of Centres of Excellence - Letters of Intent

Principal investigators: Roy, DenisClaude

$15,000

Les Cellules Souches : Mythes, Controverses et Réalité

Nominated PICIHR2011CIHR Café Scientifique Program

Principal investigators: Roy, Denis-Claude

Keywords: Cadre Règlementaire; Café Scientifique; Cellules Souches; Cellules Souches Embryonnaires; Enjeux Éthiques; Greffe De Cellules Souches; Immunothérapie Du Cancer; Médecine Régénérative; Réparation Tissulaire; Thérapie Cellulaire

$3,000

Silent Victims: Stigma Surrounding the Mentally Ill and Stress Effects on Spouse and Their Children

Co-investigatorCIHR2010Operating Grant

Principal investigators: Lupien, Sonia J

Keywords: Biomarkers; Caregivers; Mental Health; Stigma; Stress

$361,342

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Denis-Claude Roy

Research

Latest papers

Latest funding

Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders.

The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells.

Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge.

Two types of human TCR differentially regulate reactivity to self and non-self antigens.

Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome.

Negative Regulation of Zap70 by Lck Forms the Mechanistic Basis of Differential Expression in CD4 and CD8 T Cells.

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.

Stigma associated with parental depression or cancer: Impact on spouse and offspring's cortisol levels and socioemotional functioning.

Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags.

Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions.

Exploiting minor histocompatibility antigens for personalized cancer immunotherapy

CellCAN Regenerative Medicine and Cell Therapy Network

Elucidating mechanisms of MSC-induced tissue regeneration: path to mesenchymal stromal cell clinical trial in glaucoma

Clinical application of a novel molecule that expands human cord blood stem cells

KM - CellCAN RCTN - Regenerative Cell Therapy Network

Personalized Cancer Immunotherapy

RCTN - Regenerative Cell Therapy Network / Réseau de thérapie cellulaire régénérative

Les Cellules Souches : Mythes, Controverses et Réalité

Silent Victims: Stigma Surrounding the Mentally Ill and Stress Effects on Spouse and Their Children

Frequent collaborators

Lambert Busque

Jean Roy

Guy Sauvageau

Sandra Cohen

Claude Perreault

Anne Marinier

Sylvie Lesage

Samer Mansour

Francis Rodier

Isabelle Ouellet-Morin

Caroline Lamarche

Nicolas Noiseux

Nicolas Pineault

Isabelle Ouellet-Morin

David Juncker

Isabelle Ouellet-Morin

Richard Kremer

Alain Rivard