Faculty profile

Sylvie Lesage

ResearcherUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Sylvie Lesage

Researcher

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
16 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (8 CIHR, 5 NSERC), most recently in 2024.
Supervisor on 3 trainee awards (3 CIHR), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Mouse Models Cellular Immunology Immune Tolerance T Cells Immunology Affinity Maturation Antibody Antigen Challenge

Latest papers

Reversible Neutrophilia Driven by Monoclonal Gammopathy of Clinical Significance Simulating Chronic Neutrophilic Leukemia: A Case Report.
Case reports in hematology · 2026
MPN-FIT: a randomized controlled pilot trial of supervised exercise in myeloproliferative neoplasms.
Blood advances · 2026
Insights into the regulation and signaling landscape of cardiotrophin-like cytokine factor 1 (CLCF1).
Biochimica et biophysica acta. Molecular cell research · 2026 · senior author

All 53 publications

Latest funding

A histology suite for visualizing cell distribution in tissues
NSERC · 2024 · Principal investigator
$110,438
Defining the impact of genetic variation on the quality of the humoral response
CIHR · 2023 · Nominated PI
$100,000
INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)
NSERC · 2022 · Co-investigator
$733,440

All 26 grants and awards

53 publications.

Reversible Neutrophilia Driven by Monoclonal Gammopathy of Clinical Significance Simulating Chronic Neutrophilic Leukemia: A Case Report.

Larin É, Busque L, Chabot-Roy G, Lesage S, Jadot G, LeBlanc R, Roy J, Claveau JS, Szuber N

Case reports in hematology2026

DOI: 10.1155/crh/7405586 PMID: 42630736

MPN-FIT: a randomized controlled pilot trial of supervised exercise in myeloproliferative neoplasms.

Ouellet M, Rizzolo A, Venne C, Moussa H, Bilodeau K, Mollica L, Chabot-Roy G, Huynh-Trudeau G, Lesage S, Harnois M, Busque L, Sirhan S, Szuber N

Blood advances2026

DOI: 10.1182/bloodadvances.2025018682 PMID: 41499761

Insights into the regulation and signaling landscape of cardiotrophin-like cytokine factor 1 (CLCF1).

Rousseau M, Côté F, Chemtob S, Gauchat JF, Pasquin S, Lesage S

Biochimica et biophysica acta. Molecular cell research2026Senior author

DOI: 10.1016/j.bbamcr.2026.120123 PMID: 41662978

RIPK3 impacts antibody generation in an induced model of murine lupus through mechanisms other than necroptosis and antigen presentation.

Pilon C, Lonina E, Levine JS, Lesage S, Rauch J

Frontiers in immunology2025

DOI: 10.3389/fimmu.2025.1506124 PMID: 41098721

Exploratory analyses of leukocyte responses in hospitalized patients treated with ozanimod following a severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection.

Courtemanche O, Blais-Lecours P, Lesage S, Chabot-Roy G, Coderre L, Blanchet MR, Châteauvert N, Lellouche F, Marsolais D

Immunology and cell biology2025

DOI: 10.1111/imcb.70006 PMID: 40025871

NOD alleles at Idd1 and Idd2 loci drive exocrine pancreatic inflammation.

Caron L, Vdovenko D, Lombard-Vadnais F, Lesage S

Immunogenetics2024Senior author

DOI: 10.1007/s00251-024-01352-w PMID: 39207501

The Long-Acting Glucagon-Like Peptide-2 Analog Apraglutide Enhances Intestinal Protection and Survival After Chemotherapy and Allogeneic Transplantation in Mice.

Minden MD, Audiger C, Chabot-Roy G, Lesage S, Delisle JS, Biemans B, Dimitriadou V

Annals of transplantation2024

DOI: 10.12659/aot.945249 PMID: 39497378

A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.

Burelle C, Clapatiuc V, Deschênes S, Cuillerier A, De Loof M, Higgins MÈ, Boël H, Daneault C, Chouinard B, Clavet MÉ, Tessier N, Croteau I, Chabot G, Martel C, Sirois MG, Lesage S, Burelle Y, Ruiz M

Communications biology2024

DOI: 10.1038/s42003-024-06035-6 PMID: 38519536

Modified host defence peptide GF19 slows TNT-mediated spread of corneal herpes simplex virus serotype I infection.

Thathapudi NC, Callai-Silva N, Malhotra K, Basu S, Aghajanzadeh-Kiyaseh M, Zamani-Roudbaraki M, Groleau M, Lombard-Vadnais F, Lesage S, Griffith M

Scientific reports2024

DOI: 10.1038/s41598-024-53662-4 PMID: 38374240

Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure.

Caron L, Delisle JS, Strong JE, Deschambault Y, Lombard-Vadnais F, Labbé AC, Lesage S

Virology journal2023Senior author

DOI: 10.1186/s12985-023-02258-x PMID: 38087355

A histology suite for visualizing cell distribution in tissues

Principal investigatorNSERC2024Research Tools and Instruments

Principal investigators: Lesage, Sylvie

Keywords: Cellular positioning; Fluorecent microscopy; Histology; Microscopy; Tissue sections

$110,438

Defining the impact of genetic variation on the quality of the humoral response

Nominated PICIHR2023Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Lesage, Sylvie

Keywords: Affinity Maturation; Antibody; Antigen Challenge; B Cell; Genetics; Germinal Center; Humoral Response; Mouse Models; T Cell; Vaccination

$100,000

INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)

Co-investigatorNSERC2022Collaborative Research and Training Experience

Principal investigators: Alarcon, Emilio

$733,440

IMAGE-GUIDED INJECTION WITH A HIGH-RESOLUTION ULTRASOUND SYSTEM ADAPTED FOR RODENT USE

Principal investigatorNSERC2022Research Tools and Instruments

Principal investigators: Lesage, Sylvie

$146,541

Defining thymic B cell origin and function

Nominated PICIHR2022Project Grant

Principal investigators: Lesage, Sylvie

Keywords: Autoimmunity; B Cells; Cellular Immunology; Central Tolerance; Immune Tolerance; Mouse Models; T Cells; Thymus

$929,475

Systematic analysis of the molecular mechanisms of leukocyte entry into the pancreas. MRC NPA Adrian Liston

Nominated PICIHR2019Team Grant: UK-Canada Diabetes Research Team Grants

Principal investigators: Lesage, Sylvie

Keywords: Diabetes; Immunology; Leucocyte Migration; Mouse Genetics; Target Gene-Based Approach

$450,000

Immunogenetics of antibody affinity

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Lesage, Sylvie

$252,000

Sex effects in immune functions and diseases - CSI 2020

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Ramanathan, Sheela

Keywords: Canadian Society For Immunology Annual Meeting; Sex And Gender In Immune Responses

$10,000

Thymic differentiation of immunoregulatory DN T cells

Nominated PICIHR2018Project Grant

Principal investigators: Lesage, Sylvie

Keywords: Cellular Immunology; Dn T Cells; Immune Tolerance; Mouse Models; T Cells

$960,076

Roles of CLCF1 and CRLF1 in IL-23-driven autoimmune pathologies.

Co-investigatorCIHR2018Project Grant

Principal investigators: Gauchat, Jean-François M

Keywords: Autoimmunity; Cytokines; Inflammatory Bowel Diseases; Psoriasis

$749,700

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Sylvie Lesage

Research

Latest papers

Latest funding

Reversible Neutrophilia Driven by Monoclonal Gammopathy of Clinical Significance Simulating Chronic Neutrophilic Leukemia: A Case Report.

MPN-FIT: a randomized controlled pilot trial of supervised exercise in myeloproliferative neoplasms.

Insights into the regulation and signaling landscape of cardiotrophin-like cytokine factor 1 (CLCF1).

RIPK3 impacts antibody generation in an induced model of murine lupus through mechanisms other than necroptosis and antigen presentation.

Exploratory analyses of leukocyte responses in hospitalized patients treated with ozanimod following a severe acute respiratory syndrome coronavirus 2 (SARS&#x2011;CoV&#x2011;2) infection.

NOD alleles at Idd1 and Idd2 loci drive exocrine pancreatic inflammation.

The Long-Acting Glucagon-Like Peptide-2 Analog Apraglutide Enhances Intestinal Protection and Survival After Chemotherapy and Allogeneic Transplantation in Mice.

A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.

Modified host defence peptide GF19 slows TNT-mediated spread of corneal herpes simplex virus serotype I infection.

Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure.

A histology suite for visualizing cell distribution in tissues

Defining the impact of genetic variation on the quality of the humoral response

INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)

IMAGE-GUIDED INJECTION WITH A HIGH-RESOLUTION ULTRASOUND SYSTEM ADAPTED FOR RODENT USE

Defining thymic B cell origin and function

Systematic analysis of the molecular mechanisms of leukocyte entry into the pancreas. MRC NPA Adrian Liston

Immunogenetics of antibody affinity

Sex effects in immune functions and diseases - CSI 2020

Thymic differentiation of immunoregulatory DN T cells

Roles of CLCF1 and CRLF1 in IL-23-driven autoimmune pathologies.

Frequent collaborators

Sylvain Chemtob

Joyce Rauch

May Griffith

Marika Sarfati

Lambert Busque

Jean Roy

Nathalie Labrecque

CHEOLHO Cheong

Matthieu Ruiz

Yan Burelle

Marie-Claude Bourgeois-Daigneault

Sylvain Meloche

Nicolas Chomont

Karine Bilodeau

Martin Pelletier

Jacques Thibodeau

Nathalie Rivard

Denis-Claude Roy

Alain Bitton

Christine Des Rosiers

Alexandre Orthwein

Catherine Martel

David Marsolais

Nicolas Chomont

Claude Perreault

Jean-Pierre Routy

Petronela Ancuta

Jean-Pierre Routy

Exploratory analyses of leukocyte responses in hospitalized patients treated with ozanimod following a severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection.