This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Identification of essential yeast genes involved in polyamine resistance.
Gene · 2018 · senior author
UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
Scientific reports · 2018 · senior author
CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.
Neuro-oncology · 2018
Latest funding
- $68,000
Role of C. elegans AP endonuclease, APN-1, in removing DNA lesions generated through transporter-mediated uptake of naturally occurring toxic compounds.
NSERC · 2017 · Principal investigator
- $994,500
Linking defects in the uptake transporter OCT1 with cancer patients resistance towards anthracyclines
CIHR · 2016 · Nominated PI
- $92,232
A microcalorimetry system to define the biochemical parameters of molecular interactions
NSERC · 2016 · Co-investigator
23 publications.
Identification of essential yeast genes involved in polyamine resistance.
Aouida M, Ramotar D
UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
Papaluca A, Wagner JR, Saragovi HU, Ramotar D
CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.
Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A
Uncharacterized ORF HUR1 influences the efficiency of non-homologous end-joining repair in Saccharomyces cerevisiae.
Omidi K, Jessulat M, Hooshyar M, Burnside D, Schoenrock A, Kazmirchuk T, Hajikarimlou M, Daniel M, Moteshareie H, Bhojoo U, Sanders M, Ramotar D, Dehne F, Samanfar B, Babu M, Golshani A
Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2.
Saad A, Bijian K, Qiu D, da Silva SD, Marques M, Chang CH, Nassour H, Ramotar D, Damaraju S, Mackey J, Bismar T, Witcher M, Alaoui-Jamali MA
The long N-terminus of the C. elegans DNA repair enzyme APN-1 targets the protein to the nucleus of a heterologous system.
Wang Z, Yang X, Mazouzi A, Ramotar D
Functional variants of human APE1 rescue the DNA repair defects of the yeast AP endonuclease/3'-diesterase-deficient strain.
Wang Z, Ayoub E, Mazouzi A, Grin I, Ishchenko AA, Fan J, Yang X, Harihar T, Saparbaev M, Ramotar D
Upregulation of the Saccharomyces cerevisiae efflux pump Tpo1 rescues an Imp2 transcription factor-deficient mutant from bleomycin toxicity.
Berra S, Ayachi S, Ramotar D
RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation.
Jouvet N, Poschmann J, Douville J, Marrakchi R, Ramotar D
The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.
Poschmann J, Drouin S, Jacques PE, El Fadili K, Newmarch M, Robert F, Ramotar D
Role of C. elegans AP endonuclease, APN-1, in removing DNA lesions generated through transporter-mediated uptake of naturally occurring toxic compounds.
Principal investigators: Ramotar, Dindial
Linking defects in the uptake transporter OCT1 with cancer patients resistance towards anthracyclines
Principal investigators: Ramotar, Dindial
Keywords: Anticancer Agents, Anthracyclines, Cisplatin; Crispr Library; Dna Sequencing; Drug Uptake Studies; Epifluorescent Microscopy; Gene Expression Microarray Analysis; High Throughput Screens For Small Molecules; Organic Cation Transporters; Patients Samples, Acute Myeloid Leukemia And Ovarian; Uptake Transporters And Drug Resistance
A microcalorimetry system to define the biochemical parameters of molecular interactions
Principal investigators: Affar, ElBachir
A general utility centrifugation apparatus for cellular and macromolecular studies
Principal investigators: Affar, ElBachir
Biological function of the DNA repair enzyme APN-1 in C. elegans
Principal investigators: Ramotar, Dindial
The role of human glyceraldehyde-3-phosphate dehydrogenase in maintaining the redox state of the DNA repair enzyme APE1
Principal investigators: Ramotar, Dindial
Keywords: Cell Cycle; Dna Repair; Genome-Wide Location Analysis; Genomic Instability; Immunofluorescence; Oxidative Dna Damage; Oxidized Proteins; Post-Translational Modification; Protein Structure/Function Analysis; Protein-Protein Interactions
Biomolecular imaging in fundamental cell and molecular biology research
Principal investigators: Drobetsky, Elliot
The role of human glyceraldehyde-3-phosphate dehydrogenase in reactivating oxidized forms of the DNA repair enzyme APE1
Principal investigators: Ramotar, Dindial
Keywords: Cell Biology; Dna Repair; Neurological Diseases; Oxidative Dna Damage; Oxidized Proteins; Protein-Protein Interactions
Biological function of the C. elegans AP endonuclease CeAPN-1
Principal investigators: Ramotar, Dindial
Biological function of ce apni and ce exo III in c-elegans
Principal investigators: Ramotar, Dindial
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Oncology
- Medicine/Oncology
- Medicine
- Chemistry and Biochemistry
- Laboratory Medicine and Pathology
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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