Faculty profile

Frederic Charron

ResearcherMedicineUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses and email address may be missing. Find their university profile.

Frederic Charron

Researcher

Medicine

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
4 publications in the last five years, latest in 2025.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2025.
Supervised 4 trainees who won CIHR awards, most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Axon Guidance Cerebellum Medulloblastoma Shh Sonic Hedgehog Dcc Netrin Spinal Cord

Latest papers

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma.
Cell reports. Medicine · 2025
A central role for Numb/Nbl in multiple Shh-mediated axon repulsion processes.
iScience · 2025
Defining the Genetic Landscape of Congenital Mirror Movements in 80 Affected Individuals.
Movement disorders : official journal of the Movement Disorder Society · 2024

All 8 publications

Latest funding

The physiological, molecular and genetic mechanisms underlying lateralization of motor control.
CIHR · 2025 · Nominated PI
$1,208,700
Uncovering the molecular mechanism of neuronal cell migration in the cerebellum
CIHR · 2023 · Supervisor
$105,000
A role for Arhgef7 during cerebellar development
CIHR · 2023 · Supervisor
$63,750

All 15 grants and awards

8 publications.

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma.

DeCarlo A, MacLeod G, Fernandes da Silva C, Shen LQ, Povilaikaite J, Deane M, Aragao L, Sie M, Termini D, Magee J, Gudenas B, Sukumaran S, Charron F, Marcellus R, Al-Awar R, Aman A, Reynaud D, Trolat A, Wybenga-Groot L, Tabori U, Nör C, Harding SM, Moran MF, Northcott PA, Dirks P, Angers S, Ramaswamy V

Cell reports. Medicine2025

DOI: 10.1016/j.xcrm.2025.102202 PMID: 40562042

A central role for Numb/Nbl in multiple Shh-mediated axon repulsion processes.

Dolique T, Baudet S, Charron F, Ferent J

iScience2025

DOI: 10.1016/j.isci.2025.112293 PMID: 40276749

Defining the Genetic Landscape of Congenital Mirror Movements in 80 Affected Individuals.

Collins Hutchinson ML, St-Onge J, Schlienger S, Boudrahem-Addour N, Mougharbel L, Michaud JF, Lloyd C, Bruneau E, Roux C, Sahly AN, Osterman B, Myers KA, Rouleau GA, Jimenez Cruz DA, Rivière JB, Accogli A, Charron F, Srour M

Movement disorders : official journal of the Movement Disorder Society2024

DOI: 10.1002/mds.29669 PMID: 38314870

Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control.

Schlienger S, Yam PT, Balekoglu N, Ducuing H, Michaud JF, Makihara S, Kramer DK, Chen B, Fasano A, Berardelli A, Hamdan FF, Rouleau GA, Srour M, Charron F

Science advances2023Senior author

DOI: 10.1126/sciadv.add5501 PMID: 37172092

Extracellular phosphorylation in axon pathfinding.

Yam PT, Charron F

Nature chemical biology2019Senior author

DOI: 10.1038/s41589-019-0383-6 PMID: 31636433

Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.

Ferent J, Giguère F, Jolicoeur C, Morin S, Michaud JF, Makihara S, Yam PT, Cayouette M, Charron F

Neuron2019Senior author

DOI: 10.1016/j.neuron.2019.04.003 PMID: 31054872

The Shh receptor Boc is important for myelin formation and repair.

Zakaria M, Ferent J, Hristovska I, Laouarem Y, Zahaf A, Kassoussi A, Mayeur ME, Pascual O, Charron F, Traiffort E

Development (Cambridge, England)2019

DOI: 10.1242/dev.172502 PMID: 31048318

Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon.

Verwey M, Grant A, Meti N, Adye-White L, Torres-Berrío A, Rioux V, Lévesque M, Charron F, Flores C

eNeuro2016

DOI: 10.1523/eneuro.0009-16.2016 PMID: 27419218

The physiological, molecular and genetic mechanisms underlying lateralization of motor control.

Nominated PICIHR2025Project Grant

Principal investigators: Charron, Frederic; Srour, Myriam

Keywords: Axon Guidance; Dcc; Human Genetics; Lateralization Of Motor Control; Mirror Movements; Netrin; Neurodevelopment; Signaling

$1,208,700

Uncovering the molecular mechanism of neuronal cell migration in the cerebellum

SupervisorCIHR2023Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Drewnik, Dennis A

Keywords: Branched Actin Polymerization; Cerebellum; Cytoskeletal Rearrangement; Deleted In Colorectal Cancer (Dcc); Extracellular Guidance Cues; Microcephaly; Netrin-1 Signalling; Neurodevelopment; Neuronal Migration; Wave Regulatory Complex (Wrc)

$105,000

A role for Arhgef7 during cerebellar development

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Jimenez-Amilburu, Vanesa

Keywords: Arhgef7; Cdc42; Cerebellar Development; Dcc/Netrin1 Signaling; Granule Cell Precursors; Guanosine Nucleotide Exchange Factor (Gef); Nervous System Development; Neurological Diseases; Neuronal Migration; Rac1

$63,750

Investigation of a novel tumor suppressor mechanism in medulloblastoma

Nominated PICIHR2021Project Grant

Principal investigators: Charron, Frederic

Keywords: Brain Tumor; Cerebellum; Medulloblastoma; Nonsense Mediated Mrna Decay (Nmd); Patched; Pediatric Cancer; Ptch1; Shh; Sonic Hedgehog

$990,675

The role of the WAVE regulatory complex in commissural axon guidance

Nominated PICIHR2021Project Grant

Principal investigators: Charron, Frederic

Keywords: Axon Guidance; Boc; Commissural Neurons; Cytoskeleton; Dcc; Growth Cone; Netrin; Sonic Hedgehog; Spinal Cord

$994,500

Canada Research Chair - Tier 1

Nominated PICIHR2020Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Charron, Frederic

Keywords: Crc

$1,400,000

Circuit formation by spatio-temporal control of mRNA translation

Nominated PICIHR2015Joint Canada-Israel Health Research Program

Principal investigators: Charron, Frederic; Yaron, Avraham

Keywords: Axon Guidance; Developmental Neurobiology; Hedgehog Signaling; Local Translation; Mouse Genetics; Neural Circuit; Regeneration; Shh; Spinal Cord Development; Trkb

Shh signaling in normal and pathological nervous system development

Nominated PICIHR2014Foundation Grant

Principal investigators: Charron, Frederic

Keywords: Axon Guidance; Brain Tumour; Cerebellum; Hedgehog Signaling; Medulloblastoma; Nervous System Development; Neurobiology; Shh; Sonic Hedgehog; Spinal Cord

$3,591,701

Canada Research Chair Tier 1

Nominated PICIHR2014Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Charron, Frederic

Keywords: Crc

$1,400,000

Investigation of the molecular mechanisms leading to polarized Sonic Hedgehog signal transduction in axonal growth cones

SupervisorCIHR2014CIHR Fellowship

Principal investigators: Ferent, Julien

Keywords: Axon Guidance; Boc Receptor; Commissural Neurons; Growth Cone; Neural Development; Numb; Par Complex; Polarity; Sonic Hedgehog

$135,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Frederic Charron

Research

Latest papers

Latest funding

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma.

A central role for Numb/Nbl in multiple Shh-mediated axon repulsion processes.

Defining the Genetic Landscape of Congenital Mirror Movements in 80 Affected Individuals.

Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control.

Extracellular phosphorylation in axon pathfinding.

Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.

The Shh receptor Boc is important for myelin formation and repair.

Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon.

The physiological, molecular and genetic mechanisms underlying lateralization of motor control.

Uncovering the molecular mechanism of neuronal cell migration in the cerebellum

A role for Arhgef7 during cerebellar development

Investigation of a novel tumor suppressor mechanism in medulloblastoma

The role of the WAVE regulatory complex in commissural axon guidance

Canada Research Chair - Tier 1

Circuit formation by spatio-temporal control of mRNA translation

Shh signaling in normal and pathological nervous system development

Canada Research Chair Tier 1

Investigation of the molecular mechanisms leading to polarized Sonic Hedgehog signal transduction in axonal growth cones

Frequent collaborators

Myriam Srour

Myriam Srour

Vijay Ramaswamy

Cecilia Flores

Alfonso Fasano

Michel Cayouette

Ahmed Aman

Cecilia Flores

Uri Tabori

Stephane Angers