Faculty profile

Graziella Di Cristo

ResearcherNeurosciencesUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Graziella Di Cristo

Researcher

Neurosciences

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
11 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 12 research grants (9 CIHR, 3 NSERC), most recently in 2025.
Supervised 2 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Confocal Imaging Gamma Oscillations In Vivo Recording Gabaergic Circuits Autism Behaviour Biophysical Modeling Dendrites

Latest papers

Sub-Anesthetic Ketamine Administration Decreases Deviance Detection Responses at the Cellular, Population- and Mesoscale Levels.
The European journal of neuroscience · 2026 · senior author
Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex.
eLife · 2025 · senior author
Developmental Syngap1 Haploinsufficiency in Medial Ganglionic Eminence-Derived Interneurons Impairs Auditory Cortex Activity, Social Behavior, and Extinction of Fear Memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024 · senior author

All 20 publications

Latest funding

Structural effects of THC on adolescent cortex: microglial mechanisms
CIHR · 2025 · Co-investigator
$1,071,000
Cellular Basis of Learning Impairments in a mouse model of Fragile X Syndrome
CIHR · 2025 · Principal investigator
$1,074,826
Testing KW-2449 Treatment to Restore Inhibitory Function in SYNGAP1 Haploinsufficiency Using Mouse and Cortical Organoid Models
CIHR · 2025 · Supervisor
$120,000

All 19 grants and awards

20 publications.

Sub-Anesthetic Ketamine Administration Decreases Deviance Detection Responses at the Cellular, Population- and Mesoscale Levels.

Carreño-Muñoz MI, Ciancone Chama A, Chehrazi P, Chattopadhyaya B, Di Cristo G

The European journal of neuroscience2026Senior author

DOI: 10.1111/ejn.70471 PMID: 41919726

Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex.

Francavilla R, Chattopadhyaya B, Damo Kamda JL, Jadhav V, Kourrich S, Michaud JL, Di Cristo G

eLife2025Senior author

DOI: 10.7554/elife.97100 PMID: 40810392

Developmental Syngap1 Haploinsufficiency in Medial Ganglionic Eminence-Derived Interneurons Impairs Auditory Cortex Activity, Social Behavior, and Extinction of Fear Memory.

Jadhav V, Carreno-Munoz MI, Chehrazi P, Michaud JL, Chattopadhyaya B, Di Cristo G

The Journal of neuroscience : the official journal of the Society for Neuroscience2024Senior author

DOI: 10.1523/jneurosci.0946-24.2024 PMID: 39406516

Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence.

Navarri X, Robertson DN, Charfi I, Wünnemann F, Sâmia Fernandes do Nascimento A, Trottier G, Leclerc S, Andelfinger GU, Di Cristo G, Richer L, Pike GB, Pausova Z, Piñeyro G, Paus T

The Journal of neuroscience : the official journal of the Society for Neuroscience2024

DOI: 10.1523/jneurosci.2256-23.2024 PMID: 39214708

Neonatal hypoxia impairs serotonin release and cognitive functions in adult mice.

Lee KKY, Chattopadhyaya B, do Nascimento ASF, Moquin L, Rosa-Neto P, Amilhon B, Di Cristo G

Neurobiology of disease2024Senior author

DOI: 10.1016/j.nbd.2024.106465 PMID: 38460800

Editorial: GABAergic circuits in health and disease.

Topolnik L, Di Cristo G, Rossignol E

Frontiers in neural circuits2023

DOI: 10.3389/fncir.2023.1322193 PMID: 38024809

The p75 Neurotrophin Receptor in Preadolescent Prefrontal Parvalbumin Interneurons Promotes Cognitive Flexibility in Adult Mice.

Chehrazi P, Lee KKY, Lavertu-Jolin M, Abbasnejad Z, Carreño-Muñoz MI, Chattopadhyaya B, Di Cristo G

Biological psychiatry2023Senior author

DOI: 10.1016/j.biopsych.2023.04.019 PMID: 37120061

Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories.

Lavertu-Jolin M, Chattopadhyaya B, Chehrazi P, Carrier D, Wünnemann F, Leclerc S, Dumouchel F, Robertson D, Affia H, Saba K, Gopal V, Patel AB, Andelfinger G, Pineyro G, Di Cristo G

Molecular psychiatry2023Senior author

DOI: 10.1038/s41380-023-02085-0 PMID: 37131076

Syngap1 Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

Khlaifia A, Jadhav V, Danik M, Badra T, Berryer MH, Dionne-Laporte A, Chattopadhyaya B, Di Cristo G, Lacaille JC, Michaud JL

eNeuro2023

DOI: 10.1523/eneuro.0475-22.2023 PMID: 37072176

Sensory processing dysregulations as reliable translational biomarkers in SYNGAP1 haploinsufficiency.

Carreño-Muñoz MI, Chattopadhyaya B, Agbogba K, Côté V, Wang S, Lévesque M, Avoli M, Michaud JL, Lippé S, Di Cristo G

Brain : a journal of neurology2022Senior author

DOI: 10.1093/brain/awab329 PMID: 34791091

Structural effects of THC on adolescent cortex: microglial mechanisms

Co-investigatorCIHR2025Project Grant

Principal investigators: Pineyro, Graciela

Keywords: Adolescence; Cannabis; Cortex; Microglia; Phagocytosis; Pruning; Receptors (Cb2r); Thc

$1,071,000

Cellular Basis of Learning Impairments in a mouse model of Fragile X Syndrome

Principal investigatorCIHR2025Project Grant

Principal investigators: Muller, Eilif B; Di Cristo, Graziella

Keywords: Autism; Behaviour; Biophysical Modeling; Dendrites; Dendritic Spines; In-Vitro And In-Vivo Electrophysiology/Two-Photon Imaging; Learning And Memory; Neocortex; Pyramidal Neurons; Synaptic Plasticity

$1,074,826

Testing KW-2449 Treatment to Restore Inhibitory Function in SYNGAP1 Haploinsufficiency Using Mouse and Cortical Organoid Models

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Ciancone Chama, Alessandra G

Keywords: Auditory Processing; Autism; Eeg; Human-Derived Brain Organoids; Inhibition; Neurodevelopment; Syngap1 Disorder; Therapeutic Intervention

$120,000

Estrous phase and estradiol-dependent regulation of auditory perception

Nominated PICIHR2024Project Grant

Principal investigators: Di Cristo, Graziella

Keywords: Auditory Processing; Autism Spectrum Disorders; Confocal Imaging; Estrogen Receptors; Estrous Phase; Fast-Spiking Parvalbumin-Expressing Gabaergic Interneurons; Gamma Oscillations; In Vivo Recording; Patch Clamp Recording; Sensory Habituation

$1,243,125

Molecular and cellular basis of estrogen-dependent auditory cortex plasticity

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Campbell, Benjamin F

Keywords: Auditory Cortex; Circuit Function; Estrogen Receptor Signaling; In Vivo Recording; Inhibitory Neuron; Molecular Mechanisms; Parvalbumin Neuron; Sensory Perception

$135,000

Neurodevelopmental mechanisms linking cortical interneurons to autism-related phenotypes

Nominated PICIHR2023Project Grant

Principal investigators: Di Cristo, Graziella

Keywords: Confocal Imaging; Development; Fast-Spiking Interneurons; Gabaergic Circuits; In Vivo Recording; Mtorc1 Signaling; Sensory Experience; Social Behavior; Synapses; Tactile Discrimination

$1,174,275

Sex- and hormone-dependent recruitment of inhibitory neurons in rodent sensory cortex

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Di Cristo, Graziella

$102,000

Neuroprotective peptides for treatment of neurological lysosomal diseases

Co-investigatorCIHR2021Project Grant

Principal investigators: Pshezhetsky, Alexey V

Keywords: Acth; Bdnf; Gene-Targeted Mouse Models; Heparan Sulfate; Lysosomal Storage Diseases; Mri; Mucopolysaccharidosis; Neurodegeneration; Neuroprotection; Synaptic Transmission

$1,032,750

Molecular mechanisms controlling maintenance and plasticity of GABAergic circuits in the adult brain.

Nominated PICIHR2020Project Grant

Principal investigators: Di Cristo, Graziella

Keywords: Aav- Mediated Gene Expression; Conditional Knockout Mice; Cortex; Critical Period Plasticity; Fear Memory Extinction; Gabaergic Circuits; Histone De-Acetylase 2; Perineuronal Nets; Single-Cell Rna Sequencing; Synapse Plasticity

$1,005,976

Neuroprotective peptides for treatment of neurological lysosomal diseases

Co-investigatorCIHR2020Operating Grant - PA: Genetics (Bridge Funding: Research Priorities)

Principal investigators: Pshezhetsky, Alexey V

Keywords: Acth; Bdnf; Gene-Targeted Mouse Models; Heparan Sulfate; Lysosomal Storage Diseases; Mri; Mucopolysaccharidosis; Neurodegeneration; Neuroprotection; Synaptic Transmission

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Graziella Di Cristo

Research

Latest papers

Latest funding

Sub-Anesthetic Ketamine Administration Decreases Deviance Detection Responses at the Cellular, Population- and Mesoscale Levels.

Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex.

Developmental Syngap1 Haploinsufficiency in Medial Ganglionic Eminence-Derived Interneurons Impairs Auditory Cortex Activity, Social Behavior, and Extinction of Fear Memory.

Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence.

Neonatal hypoxia impairs serotonin release and cognitive functions in adult mice.

Editorial: GABAergic circuits in health and disease.

The p75 Neurotrophin Receptor in Preadolescent Prefrontal Parvalbumin Interneurons Promotes Cognitive Flexibility in Adult Mice.

Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories.

Syngap1 Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

Sensory processing dysregulations as reliable translational biomarkers in SYNGAP1 haploinsufficiency.

Structural effects of THC on adolescent cortex: microglial mechanisms

Cellular Basis of Learning Impairments in a mouse model of Fragile X Syndrome

Testing KW-2449 Treatment to Restore Inhibitory Function in SYNGAP1 Haploinsufficiency Using Mouse and Cortical Organoid Models

Estrous phase and estradiol-dependent regulation of auditory perception

Molecular and cellular basis of estrogen-dependent auditory cortex plasticity

Neurodevelopmental mechanisms linking cortical interneurons to autism-related phenotypes

Sex- and hormone-dependent recruitment of inhibitory neurons in rodent sensory cortex

Neuroprotective peptides for treatment of neurological lysosomal diseases

Molecular mechanisms controlling maintenance and plasticity of GABAergic circuits in the adult brain.

Neuroprotective peptides for treatment of neurological lysosomal diseases

Frequent collaborators

Massimo Avoli

Armen Saghatelyan

Lisa Topolnik

Elsa Rossignol

Pedro Rosa-Neto

Said Kourrich

Zdenka Pausova

Lionel Carmant

Jean-Claude Lacaille