Faculty profile
Jonathan Brouillette
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Research
Latest papers
Electrocorticographic, astrocytic and transcriptomic signatures in the triple transgenic mouse model of Alzheimer's disease submitted to stearoyl-CoA desaturase inhibition.
Neuropharmacology · 2026
Differences in blood levels of neuroligin-derived peptides in a cohort for early detection of Alzheimer's disease.
The journals of gerontology. Series A, Biological sciences and medical sciences · 2026 · senior author
Protocol for evaluating neuronal activity and neurotransmitter release following amyloid-beta oligomer injections into the rat hippocampus.
STAR protocols · 2025 · senior author
Latest funding
- $50,000
Neuroligin-1 and neuroligin-2 as blood biomarkers of prodromal Alzheimer's disease
CIHR · 2025 · Nominated PI
- $879,750
Neuroligin-1 and neuroligin-2 as blood biomarkers of prodromal Alzheimer's disease
CIHR · 2025 · Nominated PI
- $105,000
Examining the propagation of non-mutated and long form human tau between the hippocampus and entorhinal cortex in a C57BL/6 mouse model
CIHR · 2023 · Supervisor
14 publications.
Electrocorticographic, astrocytic and transcriptomic signatures in the triple transgenic mouse model of Alzheimer's disease submitted to stearoyl-CoA desaturase inhibition.
Hector A, Leduc T, da Costa Caiado MJ, Delignat-Lavaud B, Dufort-Gervais J, Daneault C, Des Rosiers C, Bourguignon C, Lina JM, Fernandes K, Brouillette J, Mongrain V
Differences in blood levels of neuroligin-derived peptides in a cohort for early detection of Alzheimer's disease.
Fernandes MGF, Pinard M, Sokullu E, Tremblay C, Gagnon JF, Calon F, Coulombe B, Brouillette J
Protocol for evaluating neuronal activity and neurotransmitter release following amyloid-beta oligomer injections into the rat hippocampus.
Hervé V, Bonenfant L, Amyot M, Balafrej R, Ali OBK, Benali H, Brouillette J
Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats.
Hector A, Provost C, Delignat-Lavaud B, Bouamira K, Menaouar CA, Mongrain V, Brouillette J
Hyperactivity Induced by Soluble Amyloid-β Oligomers in the Early Stages of Alzheimer's Disease.
Hector A, Brouillette J
Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers.
Dufort-Gervais J, Provost C, Charbonneau L, Norris CM, Calon F, Mongrain V, Brouillette J
Tau hyperphosphorylation induced by the anesthetic agent ketamine/xylazine involved the calmodulin-dependent protein kinase II.
Hector A, McAnulty C, Piché-Lemieux MÉ, Alves-Pires C, Buée-Scherrer V, Buée L, Brouillette J
Bidirectional relationships between sleep and amyloid-beta in the hippocampus.
Dufort-Gervais J, Mongrain V, Brouillette J
Cognitive Deficits Following a Post-Myocardial Infarct in the Rat Are Blocked by the Serotonin-Norepinephrine Reuptake Inhibitor Desvenlafaxine.
Malick M, Gilbert K, Brouillette J, Godbout R, Rousseau G
The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.
Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J
Neuroligin-1 and neuroligin-2 as blood biomarkers of prodromal Alzheimer's disease
Principal investigators: Brouillette, Jonathan
Keywords: Blood Biomarkers; Neuroligin-1; Neuroligin-2; Prodromal Alzheimer'S Disease
Neuroligin-1 and neuroligin-2 as blood biomarkers of prodromal Alzheimer's disease
Principal investigators: Brouillette, Jonathan
Keywords: Alzheimer'S Disease; Blood Biomarker; Mass Spectrometry; Mild Cognitive Impairment (Mci); Neuroligins
Examining the propagation of non-mutated and long form human tau between the hippocampus and entorhinal cortex in a C57BL/6 mouse model
Principal investigators: Lamontagne-Kam, Daniel
Keywords: Alzheimer'S Disease; Atac-Seq; Chronic Injection Models; Hyperphosphorylation; Microscopy; Neurodegeneration; Neuroimaging; Physiology; Rna-Seq; Tau
The impact of amyloid-induced neurodegeneration on sleep features and memory processes
Principal investigators: Brouillette, Jonathan
Keywords: Aging; Alzheimer'S Disease; Amyloid-Beta Oligomers; Animal Model; Molecular And Cellular Biology; Neurodegeneration; Sleep
Reducing the activity of the phosphatase STEP to improve memory performance during aging
Principal investigators: Brouillette, Jonathan
Keywords: Animal Model; Hippocampus; Memory Deficits; Molecular Biology; Phosphatase Step
Neuroligin-1 as a new molecular substrate of the phosphatase STEP, and its involvement in homeostatic synaptic plasticity and memory function
Principal investigators: Brouillette, Jonathan
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pierrette Gaudreau and Pierrette Gaudreau: 65 shared papers
- Guylaine Ferland and Pierrette Gaudreau: 15 shared papers
- Guylaine Ferland and Pierrette Gaudreau: 15 shared papers
- Edith Hamel and Guylaine Ferland: 1 shared paper
- Edith Hamel and Jonathan Brouillette: 1 shared paper
- Guylaine Ferland and Jonathan Brouillette: 1 shared paper
- Pierrette Gaudreau and Jonathan Brouillette: 1 shared paper
- Christine Des Rosiers and Jonathan Brouillette: 1 shared paper
- Christine Des Rosiers and Karl Fernandes: 1 shared paper
- Pierrette Gaudreau and Jonathan Brouillette: 1 shared paper
- Jonathan Brouillette and Karl Fernandes: 1 shared paper
- Physiology and Pharmacology
- Neurology and Neurosurgery
- Research Centre
- Médecine
- Sciences de l'activité physique
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Karl Fernandes
Médecine
1 shared papers, latest 2026
Edith Hamel
Neurology and Neurosurgery
1 shared papers, latest 2009
Guylaine Ferland
Research Centre
1 shared papers, latest 2018
Pierrette Gaudreau
Faculty
1 shared papers, latest 2018
Christine Des Rosiers
Faculty
1 shared papers, latest 2026
Pierrette Gaudreau
Sciences de l'activité physique
1 shared papers, latest 2018
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