Faculty profile

Christine Des Rosiers

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Christine Des Rosiers

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
13 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2015.
Supervised 2 trainees who won CIHR awards, most recently in 2012.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Chronic Inflammation Crohn'S Disease Diet (Environment)Genetics Gnotobiotic Mice (Germ-Free)Humanized Mice Inflammatory Bowel Diseases Metabolome

Latest papers

Electrocorticographic, astrocytic and transcriptomic signatures in the triple transgenic mouse model of Alzheimer's disease submitted to stearoyl-CoA desaturase inhibition.
Neuropharmacology · 2026
4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity.
bioRxiv : the preprint server for biology · 2026
Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.
Immunology and cell biology · 2025 · senior author

All 68 publications

Latest funding

A Canada-Japan integrative meta-omics approach to define diet-microbiome derived metabolites that promote IBD in genetically susceptible individuals
CIHR · 2015 · Principal investigator
Role of cGMP signaling in diabetic cardiomyopathy.
CIHR · 2012 · Supervisor
$90,000
Investigations of cardiac metabolism using mass isotopomer analysis: A paradigm for biomarker and therapy discovery.
CIHR · 2010 · Nominated PI
$739,475

All 6 grants and awards

68 publications.

Electrocorticographic, astrocytic and transcriptomic signatures in the triple transgenic mouse model of Alzheimer's disease submitted to stearoyl-CoA desaturase inhibition.

Hector A, Leduc T, da Costa Caiado MJ, Delignat-Lavaud B, Dufort-Gervais J, Daneault C, Des Rosiers C, Bourguignon C, Lina JM, Fernandes K, Brouillette J, Mongrain V

Neuropharmacology2026

DOI: 10.1016/j.neuropharm.2026.110835 PMID: 41539386

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity.

Skinner OS, Miranda M, Dong F, Struhl T, Walker MA, Schleifer G, Henke MT, Clardy J, Hirano M, De Vivo DC, Schon EA, Engelstad K, Siegmund SE, Laprise C, Des Rosiers C, Mootha VK, Sharma R

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.02.10.705117 PMID: 41727150

Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.

Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT, Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C, iGenoMed Consortium

Immunology and cell biology2025Senior author

DOI: 10.1111/imcb.70039 PMID: 40509637

An NRF2/β3-Adrenoreceptor Axis Drives a Sustained Antioxidant and Metabolic Rewiring Through the Pentose-Phosphate Pathway to Alleviate Cardiac Stress.

Michel LYM, Esfahani H, De Mulder D, Verdoy R, Ambroise J, Roelants V, Bouchard B, Fabian N, Savary J, Dewulf JP, Doumont T, Bouzin C, Haufroid V, Luiken JJFP, Nabben M, Singleton ML, Bertrand L, Ruiz M, Des Rosiers C, Balligand JL

Circulation2025

DOI: 10.1161/circulationaha.124.067876 PMID: 40071326

Insights into heart failure metabolite markers through explainable machine learning.

Baron C, Mehanna P, Daneault C, Hausermann L, Busseuil D, Tardif JC, Dupuis J, Des Rosiers C, Ruiz M, Hussin JG

Computational and structural biotechnology journal2025

DOI: 10.1016/j.csbj.2025.02.041 PMID: 40160858

A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease.

Rioux JD, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, Frayne IR, Legault JT, iGenoMed Consortium, Bitton A, Ananthakrishnan A, Lesage S, Xavier RJ, Des Rosiers C

medRxiv : the preprint server for health sciences2024

DOI: 10.1101/2024.09.19.24314034 PMID: 39371119

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Liu Y, Fillebeen C, Forest A, Botta A, Varin TV, Marette A, Burelle Y, Des Rosiers C, Pantopoulos K, Sweeney G

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2023

DOI: 10.1096/fj.202301043r PMID: 37902616

Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites.

Lefort B, Gélinas R, Forest A, Bouchard B, Daneault C, Robillard Frayne I, Roy J, Oger C, Greffard K, Galano JM, Durand T, Labarthe F, Bilodeau JF, Ruiz M, Des Rosiers C

Biochimica et biophysica acta. Molecular basis of disease2023Senior author

DOI: 10.1016/j.bbadis.2023.166843 PMID: 37558007

Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.

Ferru-Clément R, Boucher G, Forest A, Bouchard B, Bitton A, Lesage S, Schumm P, Lazarev M, Brant S, Duerr RH, McGovern DPB, Silverberg M, Cho JH, NIDDK IBD Genetics Consortium, iGenoMed Consortium, Ananthakrishnan A, Xavier RJ, Rioux JD, Des Rosiers C

Inflammatory bowel diseases2023

DOI: 10.1093/ibd/izac281 PMID: 36662167

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.

Baron C, Cherkaoui S, Therrien-Laperriere S, Ilboudo Y, Poujol R, Mehanna P, Garrett ME, Telen MJ, Ashley-Koch AE, Bartolucci P, Rioux JD, Lettre G, Des Rosiers C, Ruiz M, Hussin JG

bioRxiv : the preprint server for biology2023

DOI: 10.1101/2023.03.22.533869 PMID: 36993181

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Christine Des Rosiers

Research

Latest papers

Latest funding

Electrocorticographic, astrocytic and transcriptomic signatures in the triple transgenic mouse model of Alzheimer's disease submitted to stearoyl-CoA desaturase inhibition.

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity.

Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.

An NRF2/&#x3b2;3-Adrenoreceptor Axis Drives a Sustained Antioxidant and Metabolic Rewiring Through the Pentose-Phosphate Pathway to Alleviate Cardiac Stress.

Insights into heart failure metabolite markers through explainable machine learning.

A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease.

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites.

Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.

A Canada-Japan integrative meta-omics approach to define diet-microbiome derived metabolites that promote IBD in genetically susceptible individuals

Role of cGMP signaling in diabetic cardiomyopathy.

Investigations of cardiac metabolism using mass isotopomer analysis: A paradigm for biomarker and therapy discovery.

CIHR Team in the Leigh Syndrome French Canadian Type (LSFC): Translating LSFC gene discovery into treatments for patients

Emerging Research Team in the Leigh Syndrome French Canadian Type (LSFC): Translating LSFC gene discovery into treatments for patients

Intervention nutritionnelle pour les désordres de la bêta-oxydation des acides gras à chaîne longue.

Frequent collaborators

Matthieu Ruiz

Jean-Claude Tardif

Jean-Claude Tardif

Eric Thorin

Eric Thorin

Yan Burelle

Alain Bitton

Yan Burelle

Stephanie Fulton

Catherine Laprise

Stephanie Fulton

Gary Sweeney

Anil Nigam

Thierry Alquier

Ilan Azuelos

Jonathan Brouillette

Sylvie Lesage

Karl Fernandes

Larry Lands

Maxime Tremblay-Gravel

Julie Hussin

Richard Roy

Gaétan Mayer

Guillaume Lettre

Emile Levy

Vincent Poitout

Sabah Hussain

Lorenzo Ferri

Anne-Claude Gingras

Przemyslaw Sapieha

Jean-Sébastien Joyal

Jacek Majewski

Przemyslaw Sapieha

An NRF2/β3-Adrenoreceptor Axis Drives a Sustained Antioxidant and Metabolic Rewiring Through the Pentose-Phosphate Pathway to Alleviate Cardiac Stress.