Faculty profile
Julianna Blagih
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Research
Latest papers
Sucralose as a Way to Enhance Regulatory T Cells, the SWEET Trial: Clinical Research Protocol.
Canadian journal of kidney health and disease · 2026
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia.
Molecular metabolism · 2025
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.
Nature communications · 2025
Latest funding
- $1,032,750
Environmental vulnerabilities of CD8 T cell responses
CIHR · 2025 · Nominated PI
- $67,500
When sweet is too sweet: The impact of artificial sweeteners on postpartum breast cancer
CIHR · 2025 · Nominated PI
- $1,296,675
Dissecting the diet-dependent immune-mediated potentiation of radiotherapy in prostate cancer
CIHR · 2025 · Nominated PI
17 publications.
Sucralose as a Way to Enhance Regulatory T Cells, the SWEET Trial: Clinical Research Protocol.
Bourguignon L, Benazzouk Y, Bokou-Gianneli E, Zani F, Blagih J, Lamarche C
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia.
Ponce-Garcia FM, Jenkins YR, Assmann VD, Paul S, Sharma ND, Moore C, Ma EH, Diamanti P, Hennequart M, Blagih J, Le L, Jenkins BJ, Rouvray S, Cronin JG, Jones RG, Mansour M, Blair A, Halsey C, Matlawska-Wasowska K, Herranz D, Vincent EE, Jones N
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.
Jenkins BJ, Jenkins YR, Ponce-Garcia FM, Moscrop C, Perry IA, Hitchings MD, Uribe AH, Bernuzzi F, Eastham S, Cronin JG, Berisha A, Howell A, Davies J, Blagih J, Williams M, Marsden M, Veale DJ, Davies LC, Niphakis M, Finlay DK, Sinclair LV, Cravatt BF, Hogan AE, Nathan JA, Humphreys IR, Fearon U, Sumpton D, Vande Voorde J, Vale GDD, McDonald JG, Jones GW, Pearson JA, Vincent EE, Jones N
ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.
Jenkins BJ, Jenkins YR, Ponce-Garcia FM, Moscrop C, Perry IA, Hitchings MD, Uribe AH, Bernuzzi F, Eastham S, Cronin JG, Berisha A, Howell A, Davies J, Blagih J, Veale DJ, Davies LC, Niphakis M, Finlay DK, Sinclair LV, Cravatt BF, Hogan AE, Nathan JA, Fearon U, Sumpton D, Vande Voorde J, Dias do Vale G, McDonald JG, Jones GW, Pearson JA, Vincent EE, Jones N
Loss of attachment promotes proline accumulation and excretion in cancer cells.
Pilley SE, Hennequart M, Vandekeere A, Blagih J, Legrave NM, Fendt SM, Vousden KH, Labuschagne CF
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
Hennequart M, Pilley SE, Labuschagne CF, Coomes J, Mervant L, Driscoll PC, Legrave NM, Lee Y, Kreuzaler P, Macintyre B, Panina Y, Blagih J, Stevenson D, Strathdee D, Schneider-Luftman D, Grönroos E, Cheung EC, Yuneva M, Swanton C, Vousden KH
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses.
Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH
Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR
Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis.
Tzelepis F, Blagih J, Khan N, Gillard J, Mendonca L, Roy DG, Ma EH, Joubert P, Jones RG, Divangahi M
Environmental vulnerabilities of CD8 T cell responses
Principal investigators: Blagih, Julianna
Keywords: Cd8 T Cells; Cellular Metabolism; Differentiation; Epigenetic; Evironmental Exposures; Listeria Monocytogenes; Metabolomics; Mitochondria; Sucralose; T Cell Memory
When sweet is too sweet: The impact of artificial sweeteners on postpartum breast cancer
Principal investigators: Blagih, Julianna
Keywords: Cancer
Dissecting the diet-dependent immune-mediated potentiation of radiotherapy in prostate cancer
Principal investigators: Blagih, Julianna; Labbé, David
Keywords: Adaptive Immunity; Anti-Tumour Immunity; Cellular Metabolism; Dietary Intervention; Immune Profiling; Immunotherapy; Mouse Models; Prostate Cancer; Radiotherapy; Tumour Immune Microenvironment
Regulatory T cells (Tregs): a new therapeutic target for uremic cardiomyopathy?
Principal investigators: Lamarche, Caroline
Keywords: Chronic Kidney Disease; Immunotherapy; Regulatory T Cells; Tregs; Uremic Cardiomyopathy; Uremic Toxins
A histology suite for visualizing cell distribution in tissues
Principal investigators: Lesage, Sylvie
Keywords: Cellular positioning; Fluorecent microscopy; Histology; Microscopy; Tissue sections
Defining the impact of genetic variation on the quality of the humoral response
Principal investigators: Lesage, Sylvie
Keywords: Affinity Maturation; Antibody; Antigen Challenge; B Cell; Genetics; Germinal Center; Humoral Response; Mouse Models; T Cell; Vaccination
Regulation of glycolysis in T cell metabolic reprogramming
Principal investigators: Blagih, Julianna
Deciphering the function of new corneal macrophages
Principal investigators: Thanabalasuriar, Ajitha AT
Keywords: Cornea; immune cells; Macrophages; metabolism; Microscopy; tissue injury
Regulation of glycolysis in T cell metabolic reprogramming
Principal investigators: Blagih, Julianna
Keywords: cellular metabolism; enzymatic function; T cell activation; T cell function; T cell proliferation; TIGAR
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Biochemistry
- Oncology
- Obstetrics and Gynecology
- Medicine
- Nephrology
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Maziar Divangahi
Medicine
2 shared papers, latest 2018
Caroline Lamarche
Nephrology
1 shared papers, latest 2026
Morag Park
Oncology
1 shared papers, latest 2018
Jerry Pelletier
Biochemistry
1 shared papers, latest 2015
Julie St-Pierre
Faculty
1 shared papers, latest 2012
Arnim Pause
Biochemistry
1 shared papers, latest 2015
Morag Park
Oncology
1 shared papers, latest 2018
Nahum Sonenberg
Biochemistry
1 shared papers, latest 2018
Philippe Joubert
Faculty
1 shared papers, latest 2018
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