Faculty profile

Pierre Thibault

ResearcherUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Pierre Thibault

Researcher

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
30 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 15 research grants (11 NSERC, 4 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Chemogenomic Vulnerability Immunopeptidome Primary T-All Samples T-Cell Acute Lymphoblastic Leukemia (T-All)Tumor Specific Antigen

Latest papers

Decoding the SUMO Proteome: A Mass Spectrometry Workflow for Site-Specific Identification.
Methods in molecular biology (Clifton, N.J.) · 2026 · senior author
An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.
Journal of cell science · 2026
Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.
Brain : a journal of neurology · 2026

All 86 publications

Latest funding

Time-of-Flight spectrometer for urgent resumption of accurate mass services.
NSERC · 2024 · Co-investigator
$150,000
Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia
CIHR · 2023 · Principal investigator
$856,800
Next generation immunopeptidomics
NSERC · 2023 · Principal investigator
$134,000

All 29 grants and awards

86 publications.

Decoding the SUMO Proteome: A Mass Spectrometry Workflow for Site-Specific Identification.

Li C, Thibault P

Methods in molecular biology (Clifton, N.J.)2026Senior author

DOI: 10.1007/978-1-0716-5166-7_3 PMID: 42542521

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

Goldman A, Nguyen M, Lanoix J, Li C, Fahmy A, Xu YZ, Schurr E, Thibault P, Desjardins M, McBride HM

Journal of cell science2026

DOI: 10.1242/jcs.264977 PMID: 42206576

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.

Da Silva A, Fallah MS, Tene Tadoum SB, Fazeli M, Muffels IJJ, Wang S, Grenier F, Budhraja R, Sturiale L, Messina A, Giladi M, Taherzadeh M, Bonneil É, Khan S, Vruchte DT, Yamanaka Y, Di Cristo G, Hamdan FF, Platt FM, Tomatsu S, Haitin Y, Kozicz T, Thibault P, Garozzo D, Pandey A, Morava E, Rossignol E, Pshezhetsky AV

Brain : a journal of neurology2026

DOI: 10.1093/brain/awag304 PMID: 42725623

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopeptidome in MSI and MSS Tumors.

Courcelles M, Hardy MP, Durette C, Lanoix J, Minati R, Laverdure JP, Vincent K, Perreault C, Thibault P

Molecular & cellular proteomics : MCP2026Senior author

DOI: 10.1016/j.mcpro.2026.101581 PMID: 42106149

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

Coulombe-Huntington J, Bertomeu T, Huard C, Chatr-Aryamontri A, St-Cyr DJ, Sánchez-Osuna M, Papadopoli D, Normandin K, Paydar M, McLaughlan S, St-Denis C, Zhang L, Say H, Palou R, Stark C, Breitkreutz BJ, van der Sloot AM, Manohar S, Lavoie H, Borden KLB, Raught B, D'Amours D, Sicheri F, Verreault A, Mader S, Meloche S, Therrien M, Thibault P, Wilhelm B, Dirks PB, Aitchison JD, Patton E, King RW, Roux PP, Sauvageau G, Hoang T, Marinier A, Harrington L, Kwok B, Archambault V, Topisirovic I, Tyers M

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.01.28.701823 PMID: 41659671

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.

Moison C, Mendoza-Sanchez R, Gracias D, Schuetz DA, Spinella JF, Girard S, Thavonekham B, Chagraoui J, Durand A, Fortier S, MacRae T, Bonneil E, Rose Y, Mayotte N, Boivin I, Thibault P, Hébert J, Ruel R, Marinier A, Sauvageau G

EMBO reports2025

DOI: 10.1038/s44319-025-00448-y PMID: 40295725

Epitope and Paratope Mapping of a SUMO-Remnant Antibody Using Cross-Linking Mass Spectrometry and Molecular Docking.

Comtois-Marotte S, Bonneil É, Li C, Smith MJ, Thibault P

Journal of proteome research2025Senior author

DOI: 10.1021/acs.jproteome.4c00717 PMID: 39965925

Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis.

Li J, Wang X, Jordana L, Bonneil É, Ginestet V, Ahmed M, Bourouh M, Pascariu CM, Schmeing TM, Thibault P, Archambault V

eLife2025

DOI: 10.7554/elife.104233 PMID: 39964262

Bcl7b and Bcl7c subunits of BAF chromatin remodeling complexes are largely dispensable for hematopoiesis.

Priam P, Krasteva V, Polsinelli A, Côté L, Dilauro F, Poinsignon TM, Thibault P, Lessard JA

Experimental hematology2025

DOI: 10.1016/j.exphem.2025.104769 PMID: 40187480

CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

Minati R, Cahuzac M, Perrault J, Lullier V, Apavaloaei A, Bonneil E, Courcelles M, Lanoix J, Kina E, Perreault C, Thibault P

Cell reports2025Senior author

DOI: 10.1016/j.celrep.2025.116676 PMID: 41391145

Time-of-Flight spectrometer for urgent resumption of accurate mass services.

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Cecioni, Samy

Keywords: Analytical biochemistry; Biomolecule analysis; High-resolution mass spectrometry; Organic synthesis; Time-of-Flight MS

$150,000

Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia

Principal investigatorCIHR2023Project Grant

Principal investigators: Hoang, Trang K; Perreault, Claude; Thibault, Pierre

Keywords: Chemogenomic Vulnerability; Immunopeptidome; Primary T-All Samples; T-Cell Acute Lymphoblastic Leukemia (T-All); Tumor Specific Antigen

$856,800

Next generation immunopeptidomics

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Thibault, Pierre

Keywords: Affinity chromatography; immunopeptidomics; Ion mobility; Mass spectrometry; Peptide antigens; Peptide sequencing; Protein SUMOylation; Proteomics; Separation sciences; Ubiquitin-like modifiers

$134,000

Neuroprotective peptides for treatment of neurological lysosomal diseases

Co-investigatorCIHR2021Project Grant

Principal investigators: Pshezhetsky, Alexey V

Keywords: Acth; Bdnf; Gene-Targeted Mouse Models; Heparan Sulfate; Lysosomal Storage Diseases; Mri; Mucopolysaccharidosis; Neurodegeneration; Neuroprotection; Synaptic Transmission

$1,032,750

Neuroprotective peptides for treatment of neurological lysosomal diseases

Co-investigatorCIHR2020Operating Grant - PA: Genetics (Bridge Funding: Research Priorities)

Principal investigators: Pshezhetsky, Alexey V

Keywords: Acth; Bdnf; Gene-Targeted Mouse Models; Heparan Sulfate; Lysosomal Storage Diseases; Mri; Mucopolysaccharidosis; Neurodegeneration; Neuroprotection; Synaptic Transmission

$100,000

Bioluminescence resonance energy transfer detection system for the monitoring of protein-protein interactions, post-translational modifications and cell signalling.

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: Bouvier, Michel

$94,371

New proteomic methods to understand the regulation of ubiquitin-like modifiers in human diseases

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Thibault, Pierre

$320,000

Characterization of endothelial cell death biomarkers for better prediction and prevention of renal fibrosis triggered by acute kidney injury

Co-investigatorCIHR2017Project Grant

Principal investigators: Hébert, Marie-Josée

Keywords: Acute Kidney Injury; Apoptosis; Biomarkers; Caspase-3; Endothelium; Microvasculature; Necroptosis; Proteomics

$707,625

RAS-MAPK signal transduction in normal and cancer cells

Co-investigatorCIHR2017Foundation Grant

Principal investigators: Therrien, Marc

Keywords: Signal Transduction

$3,273,064

Systems biology of cell size homeostasis

Co-investigatorCIHR2016Project Grant

Principal investigators: Tyers, Michael D

Keywords: Biochemistry; Biological Network; Cell Division; Cell Growth; Cell Size Homeostasis; Crispr/Cas9; Mass Spectrometry; Mathematical Modeling; Phosphoproteomics; Systematic Genetics

$573,375

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Pierre Thibault

Research

Latest papers

Latest funding

Decoding the SUMO Proteome: A Mass Spectrometry Workflow for Site-Specific Identification.

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death.

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits.

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopeptidome in MSI and MSS Tumors.

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.

Epitope and Paratope Mapping of a SUMO-Remnant Antibody Using Cross-Linking Mass Spectrometry and Molecular Docking.

Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis.

Bcl7b and Bcl7c subunits of BAF chromatin remodeling complexes are largely dispensable for hematopoiesis.

CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

Time-of-Flight spectrometer for urgent resumption of accurate mass services.

Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia

Next generation immunopeptidomics

Neuroprotective peptides for treatment of neurological lysosomal diseases

Neuroprotective peptides for treatment of neurological lysosomal diseases

Bioluminescence resonance energy transfer detection system for the monitoring of protein-protein interactions, post-translational modifications and cell signalling.

New proteomic methods to understand the regulation of ubiquitin-like modifiers in human diseases

Characterization of endothelial cell death biomarkers for better prediction and prevention of renal fibrosis triggered by acute kidney injury

RAS-MAPK signal transduction in normal and cancer cells

Systems biology of cell size homeostasis

Frequent collaborators

Claude Perreault

Sylvain Meloche

Guy Sauvageau

Etienne Caron

Alain Verreault

Anne Marinier

Marc Therrien

Vincent Archambault

Nathalie Grandvaux

Corina Nagy

Mick Bhatia

Hugo Wurtele

Ivan Topisirovic

Gustavo Turecki

Naguib Mechawar

Sylvie Mader

Sylvie Mader

Ivan Topisirovic

Jason Karamchandani

Jason Karamchandani

Damien D'Amours

Martin Sauvageau