Faculty profile

Silvy Lachance

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ProfessorDepartment of MedicineUniversité de Montréal

Signals and details

Research

Read how they describe their research on their Université de Montréal profile.

Latest papers

Tumor flare pain reaction following bispecific T-Cell engagers in multiple myeloma: a unique and underrecognized toxicity.
Haematologica · 2026
Comparison of Outcomes after UM171-Expanded Cord Blood and Six Conventional Donor Source Transplants: A Matched Analysis from the EBMT Registry.
Transplantation and cellular therapy · 2025
Management of liver sinusoidal obstruction syndrome/veno-occlusive disease in adults: a 2025 perspective from an international expert group.
Bone marrow transplantation · 2025

All 21 publications

Latest funding

Clinical application of a novel molecule that expands human cord blood stem cells
CIHR · 2014 · Co-investigator
$1,013,167

All 1 grants and awards

21 publications.

Tumor flare pain reaction following bispecific T-Cell engagers in multiple myeloma: a unique and underrecognized toxicity.

Jadot G, Sabouret A, Couture A, Laflamme L, Larose F, Ahmad I, Benkirane K, Delisle JS, Fleury I, Lachance S, LeBlanc R, Roy J, Thiant S, Veilleux O, Claveau JS

Haematologica2026Open Access

DOI: 10.3324/haematol.2025.289122 PMID: 41885028

Comparison of Outcomes after UM171-Expanded Cord Blood and Six Conventional Donor Source Transplants: A Matched Analysis from the EBMT Registry.

Cohen S, Labopin M, Bambace N, Ahmad I, Dumont-Lagacé M, Ciceri F, McLornan DP, Labussière-Wallet H, Kröger N, de Latour RP, Chalandon Y, Forcade E, Cluzeau T, Jindra P, Kulagin A, Roy J, Lachance S, Barabé F, Caudrelier P, Sauvageau G, Yakoub-Agha I, Mohty M

Transplantation and cellular therapy20254 citationsOpen Access

DOI: 10.1016/j.jtct.2025.08.006 PMID: 40818826

Management of liver sinusoidal obstruction syndrome/veno-occlusive disease in adults: a 2025 perspective from an international expert group.

Larue M, Malard F, Alaskar AS, Aljurf M, Arat M, Balsat M, Baron F, Basak G, Bazarbachi A, Bonifazi F, Brissot E, Ciceri F, Corbacioglu S, Dignan F, Huynh A, Kenyon M, Kuball J, Lachance S, Masszi T, Nagler A, Okamoto S, Pagliuca A, Ruggeri A, Ruutu T, Yakoub-Agha I, Ye Y, Duarte RF, Perić Z, Carreras E, Mohty M

Bone marrow transplantation2025

DOI: 10.1038/s41409-025-02598-y PMID: 40263636

Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment.

Serroukh Y, Hébert J, Busque L, Mercier F, Rudd CE, Assouline S, Lachance S, Delisle JS

Blood reviews202326 citationsOpen Access

DOI: 10.1016/j.blre.2022.100991 PMID: 35941029

Two types of human TCR differentially regulate reactivity to self and non-self antigens.

Trofimov A, Brouillard P, Larouche JD, Séguin J, Laverdure JP, Brasey A, Ehx G, Roy DC, Busque L, Lachance S, Lemieux S, Perreault C

iScience202228 citationsOpen Access

DOI: 10.1016/j.isci.2022.104968 PMID: 36111255

Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study.

LeBlanc R, Ahmad I, Terra R, Boudreault JS, Ogez D, Lamore K, Delisle JS, Bambace N, Bernard L, Cohen S, Kiss T, Lachance S, Landais S, Lemieux-Blanchard É, Sauvageau G, Sebag M, Roy DC, Roy J

Bone marrow transplantation202213 citations

DOI: 10.1038/s41409-021-01532-2 PMID: 34845367

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.

Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, Lemieux S, Perreault C, Rodier F, Dufresne SF, Busque L, Lachance S, Sauvageau G, Cohen S, Delisle JS

Transplantation and cellular therapy202128 citationsOpen Access

DOI: 10.1016/j.bbmt.2020.09.031 PMID: 33022376

Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.

Cohen S, Roy J, Lachance S, Delisle JS, Marinier A, Busque L, Roy DC, Barabé F, Ahmad I, Bambace N, Bernard L, Kiss T, Bouchard P, Caudrelier P, Landais S, Larochelle F, Chagraoui J, Lehnertz B, Corneau S, Tomellini E, van Kampen JJA, Cornelissen JJ, Dumont-Lagacé M, Tanguay M, Li Q, Lemieux S, Zandstra PW, Sauvageau G

The Lancet. Haematology2020210 citations

DOI: 10.1016/s2352-3026(19)30202-9 PMID: 31704264

Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group.

Mohty M, Malard F, Abecasis M, Aerts E, Alaskar AS, Aljurf M, Arat M, Bader P, Baron F, Basak G, Bazarbachi A, Blaise D, Ciceri F, Corbacioglu S, Dalle JH, Dignan F, Fukuda T, Huynh A, Kuball J, Lachance S, Lazarus H, Masszi T, Michallet M, Nagler A, NiChonghaile M, Okamoto S, Pagliuca A, Peters C, Petersen FB, Richardson PG, Ruutu T, Saber W, Savani BN, Soiffer R, Styczynski J, Wallhult E, Yakoub-Agha I, Duarte RF, Carreras E

Bone marrow transplantation2020

DOI: 10.1038/s41409-019-0705-z PMID: 31576023

Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

Christopher Lemieux, Imran Nazir Ahmad, Nadia M. Bambace, Léa Bernard, Sandra Sharpe Cohen, Jean‐Sébastien Delisle, Isabelle Fleury, Thomas L. Kiss, Luigina R. Mollica, Denis-Claude Roy, Guy Sauvageau, Jean Roy, Silvy Lachance

Transplantation and Cellular Therapy201920 citationsSenior authorOpen Access

DOI: 10.1016/j.bbmt.2019.09.007 PMID: 31521818

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Silvy Lachance

Research

Latest papers

Latest funding

Tumor flare pain reaction following bispecific T-Cell engagers in multiple myeloma: a unique and underrecognized toxicity.

Comparison of Outcomes after UM171-Expanded Cord Blood and Six Conventional Donor Source Transplants: A Matched Analysis from the EBMT Registry.

Management of liver sinusoidal obstruction syndrome/veno-occlusive disease in adults: a 2025 perspective from an international expert group.

Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment.

Two types of human TCR differentially regulate reactivity to self and non-self antigens.

Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study.

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.

Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.

Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group.

Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

Clinical application of a novel molecule that expands human cord blood stem cells

Frequent collaborators

Jean Roy

Denis-Claude Roy

Sandra Cohen

Guy Sauvageau

Jean-Sébastien Delisle

Imran Ahmad

Lambert Busque

Sébastien Lemieux

Tania Bubela

Claude Perreault

Frédéric Barabé

Caroline Letendre

Louis Laflamme

Julie Bergeron

Peter Zandstra

Ann Clarke

Sasha Bernatsky

Anne Marinier

Christopher Rudd

Bertrand Routy

Francis Rodier

David Ogez

Michael Sebag