Roseline Godbout, University of Alberta

Research

Polyunsaturated Fatty Acids Brain Fatty Acid-Binding Protein Cell Migration Malignant Glioma Peroxisome Proliferator-Activated Receptor Radial Glia Transcription Factor Fatty Acid Binding Protein

Latest papers

Glioblastoma tumor microtubes and brain fatty acid-binding protein: Path to directional infiltration.
Neuro-oncology · 2025 · senior author
Multiple anti-tumor programs are activated by blocking BAD phosphorylation.
Oncogene · 2025
PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress.
Cell reports · 2024

All 68 publications

Latest funding

Polyunsaturated Fatty Acids and the Proteins That Bind Them: Driving Glioblastoma Growth and Infiltration in Brain
CIHR · 2023 · Nominated PI
$990,676
Understanding Cellular Response to Stress: Role of DEAD Box 1
CIHR · 2018 · Nominated PI
$898,875
Role of Brain Fatty Acid-binding Protein in Malignant Glioma Progression
CIHR · 2013 · Nominated PI
$723,341

All 6 grants and awards

68 publications.

01

Glioblastoma tumor microtubes and brain fatty acid-binding protein: Path to directional infiltration.

Choi WS, Jeon P, Peyton S, Garg M, Githaka JM, Liu RZ, Glubrecht DD, Bukhari AB, McGinn D, Yasmin L, Mak C, Xu X, Larocque MP, Sun X, van Landeghem FKH, Au K, Goping IS, Godbout R

Neuro-oncology2025Senior author

DOI: 10.1093/neuonc/noaf200 PMID: 40891350

02

Multiple anti-tumor programs are activated by blocking BAD phosphorylation.

Githaka JM, Kirschenman R, Patel N, Tripathi N, Wang J, Li L, Muranyi H, Pirayeshfard L, Montpetit R, Glubrecht DD, Lerner EP, Perry T, Danial NN, Nation PN, Godbout R, Goping IS

Oncogene2025

DOI: 10.1038/s41388-025-03420-1 PMID: 40316741

03

PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress.

Mashayekhi F, Ganje C, Caron MC, Heyza JR, Gao Y, Zeinali E, Fanta M, Li L, Ali J, Mersaoui SY, Schmidt JC, Godbout R, Masson JY, Weinfeld M, Ismail IH

Cell reports2024

DOI: 10.1016/j.celrep.2024.115066 PMID: 39671289

04

CDK-dependent phosphorylation regulates PNKP function in DNA replication.

Mashayekhi F, Zeinali E, Ganje C, Fanta M, Li L, Godbout R, Weinfeld M, Ismail IH

The Journal of biological chemistry2024

DOI: 10.1016/j.jbc.2024.107880 PMID: 39395804

05

Docetaxel-Induced Cell Death Is Regulated by a Fatty Acid-Binding Protein 12-Slug-Survivin Pathway in Prostate Cancer Cells.

Liu RZ, Garg M, Yang XH, Godbout R

International journal of molecular sciences2024Senior author

DOI: 10.3390/ijms25179669 PMID: 39273616

06

Overcoming retinoic acid resistance in HER2-enriched breast cancers: role of MYC.

Choi WS, Liu RZ, Mak C, Maadi H, Godbout R

The FEBS journal2024Senior author

DOI: 10.1111/febs.17151 PMID: 38708519

07

Nuclear translocation matters: Role of FABP7 in driving glioblastoma stemness and invasion: Reply to Mu et al.

Liu RZ, Choi WS, Godbout R

Neuro-oncology2024Senior author

DOI: 10.1093/neuonc/noad239 PMID: 38244229

08

Role of DDX1 in the oxidative response of ataxia telangiectasia patient-derived fibroblasts.

Garg M, Li L, Godbout R

Redox biology2024Senior author

DOI: 10.1016/j.redox.2023.102988 PMID: 38096740

09

Stationary-to-migratory transition in glioblastoma stem-like cells driven by a fatty acid-binding protein 7-RXRα neurogenic pathway.

Liu RZ, Choi WS, Jain S, Xu X, Elsherbiny ME, Glubrecht DD, Tessier AG, Easaw JC, Fallone BG, Godbout R

Neuro-oncology2023Senior author

DOI: 10.1093/neuonc/noad134 PMID: 37499046

10

RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma.

Zhou J, Kong YS, Vincent KM, Dieters-Castator D, Bukhari AB, Glubrecht D, Liu RZ, Quilty D, Findlay SD, Huang X, Xu Z, Yang RZ, Zhang L, Tang E, Lajoie G, Eisenstat DD, Gamper AM, Fahlman R, Godbout R, Postovit LM, Fu Y

Molecular oncology2023

DOI: 10.1002/1878-0261.13434 PMID: 37057706