Edwin Wang, University of Calgary

Research

Cancer Vitamin A

Latest papers

Evaluating Somatic Mutational Contamination in Large-Scale Germline Genomic Studies.
Biology · 2026
Erratum to: Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis.
MedScience · 2026
A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy.
EBioMedicine · 2024 · senior author

All 34 publications

Latest funding

A systematic approach to understand the mechanism of immune cell infiltration and to enhance efficacy of immunotherapy in solid tumors
CIHR · 2020 · Supervisor
$135,000
Association of vitamin A intake with cancer risk in NK cell defective-associated individuals
CIHR · 2019 · Nominated PI
$75,000
Multi-sensor Fusion and Signal Processing for Massive Amount of Data
NSERC · 2018 · Co-investigator
$139,110

All 6 grants and awards

34 publications.

01

Evaluating Somatic Mutational Contamination in Large-Scale Germline Genomic Studies.

Ji X, Bai X, He G, Yan K, Wang E, Tang YD, Chen L, Cui Q

Biology2026

DOI: 10.3390/biology15141204 PMID: 42510750

02

Erratum to: Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis.

Xian W, Asad M, Wu S, Bai Z, Li F, Lu J, Zu G, Brintnell E, Chen H, Mao Y, Zhou G, Liao B, Wu J, Wang E, You L

MedScience2026

DOI: 10.1007/s11684-026-1253-8 PMID: 42223858

03

A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy.

Nasr S, Li L, Asad M, Moridi M, Wang M, Zemp FJ, Mahoney DJ, Wang E

EBioMedicine2024Senior author

DOI: 10.1016/j.ebiom.2024.105167 PMID: 38805852

04

DVA: predicting the functional impact of single nucleotide missense variants.

Wang D, Li J, Wang E, Wang Y

BMC bioinformatics2024

DOI: 10.1186/s12859-024-05709-6 PMID: 38448823

05

Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment.

Bonni S, Brindley DN, Chamberlain MD, Daneshvar-Baghbadorani N, Freywald A, Hemmings DG, Hombach-Klonisch S, Klonisch T, Raouf A, Shemanko CS, Topolnitska D, Visser K, Vizeacoumar FJ, Wang E, Gibson SB

Cancers2024

DOI: 10.3390/cancers16050911 PMID: 38473273

06

Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis.

Xian W, Asad M, Wu S, Bai Z, Li F, Lu J, Zu G, Brintnell E, Chen H, Mao Y, Zhou G, Liao B, Wu J, Wang E, You L

Frontiers of medicine2024

DOI: 10.1007/s11684-023-1017-7 PMID: 37955814

07

Application of Single-Cell Assay for Transposase-Accessible Chromatin with High Throughput Sequencing in Plant Science: Advances, Technical Challenges, and Prospects.

Lu C, Wei Y, Abbas M, Agula H, Wang E, Meng Z, Zhang R

International journal of molecular sciences2024

DOI: 10.3390/ijms25031479 PMID: 38338756

08

SPIDE: A single cell potency inference method based on the local cell-specific network entropy.

Zheng R, Xu Z, Zeng Y, Wang E, Li M

Methods (San Diego, Calif.)2023

DOI: 10.1016/j.ymeth.2023.11.006 PMID: 37952704

09

A Self-attention Graph Convolutional Network for Precision Multi-tumor Early Diagnostics with DNA Methylation Data.

Jiang X, Li Z, Mehmood A, Wang H, Wang Q, Chu Y, Mao X, Zhao J, Jiang M, Zhao B, Lin G, Wang E, Wei D

Interdisciplinary sciences, computational life sciences2023

DOI: 10.1007/s12539-023-00563-1 PMID: 37247186

10

Deciphering gene contributions and etiologies of somatic mutational signatures of cancer.

Ji X, Wang E, Cui Q

Briefings in bioinformatics2023

DOI: 10.1093/bib/bbad017 PMID: 36682004

A systematic approach to understand the mechanism of immune cell infiltration and to enhance efficacy of immunotherapy in solid tumors

SupervisorCIHR2020CIHR Fellowship

Principal investigators: Li, Lin

Keywords: Anti-Pd1 Therapy; Bioinformatics; Crispr; Hot And Cold Tumor; Immune Cell Infiltration; Immunotherapy; Single Cell Sequencing; Syngeneic Mouse Model

$135,000

Association of vitamin A intake with cancer risk in NK cell defective-associated individuals

Nominated PICIHR2019Op Gr: Data Analysis Using Existing Databases n Cohorts-Cancer Prevention n Ctrl

Principal investigators: Wang, Edwin

Keywords: Cancer; Vitamin A

$75,000

Multi-sensor Fusion and Signal Processing for Massive Amount of Data

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Leung, Henry

$139,110

Examining the etiology of young-onset breast cancer in the Canadian Partnership for Tomorrow Project

Co-investigatorCIHR2017Operating Grant: Secondary Data Analysis for Cancer Prevention and Control

Principal investigators: Brenner, Darren M

Keywords: Breast Cancer; Cohort Study; Etiology; Gene Expression; Menopausal Status; Obesity; Risk Factors

$99,659

Mapping genotypes into human face phenotypes

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Wang, Edwin

$140,000

CIHR Training Program in Integrative Approaches to Human Health

Co-investigatorCIHR2008Training Grant

Principal investigators: Hallett, Michael T

Keywords: Bioinformatics; Cancer; Complex Diseases; Computational Biology; Genomics; Imaging; Mathematical Modelling; Orphan Diseases; Proteomics; Quantitative Biology; Systems Biology

$1,766,127

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Oncology
Biochemistry and Molecular Biology
Microbiologie et immunologie
School of Population and Public Health
Human Anatomy & Cell Science
Other

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Christine Friedenreich

Oncology

1 shared papers, latest 2021

Arnaud Droit

Microbiologie et immunologie

1 shared papers, latest 2021

Andrew Freywald

Oncology

1 shared papers, latest 2024

Mark Trifiro

Faculty

1 shared papers, latest 2017

Thomas Klonisch

Human Anatomy & Cell Science

1 shared papers, latest 2024

Nicholas Provart

Faculty

1 shared papers, latest 2019

Rachel Murphy

School of Population and Public Health

1 shared papers, latest 2021

Sabine Hombach-Klonisch

Faculty

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2019

Subject: Prospective PhD student: Cancer Dear Professor Wang, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Evaluating Somatic Mutational Contamination in Large-Scale Germline Genomic Studies." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Association of vitamin A intake with cancer risk in NK cell defective-associated individuals" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]