Guang Sun, Memorial University of Newfoundland

Research

Advanced-Glycation End-Products Diabetes Mellitus Glucose Transporter 1 Metabolic Markers Methylglyoxal Osteoarthritis

Latest papers

Distinct Gut Microbiomic and Metabolomic Signatures in Knee and Hip Osteoarthritis.
The Journal of rheumatology · 2026
Altered gut microbiota and host pathways in obesity-related knee osteoarthritis.
Clinical and experimental rheumatology · 2026
Significant reverse association between dietary selenium intake and visceral adiposity in the CODING study.
Scientific reports · 2025 · senior author

All 68 publications

Latest funding

Refining the molecular endotypes for precision medicine of osteoarthritis
CIHR · 2020 · Co-investigator
$971,550
The link between osteoarthritis and diabetes mellitus
CIHR · 2015 · Principal investigator
$100,000
Discovering the neuroendocrine features of obesity with food addiction
CIHR · 2012 · Supervisor
$8,750

All 4 grants and awards

68 publications.

01

Distinct Gut Microbiomic and Metabolomic Signatures in Knee and Hip Osteoarthritis.

Huang J, Liu M, Zhang H, Sun G, Furey A, Rahman P, Zhai G

The Journal of rheumatology2026

DOI: 10.3899/jrheum.2025-1148 PMID: 42386282

02

Altered gut microbiota and host pathways in obesity-related knee osteoarthritis.

Huang J, Liu M, Zhang H, Sun G, Furey A, Rahman P, Zhai G

Clinical and experimental rheumatology2026

DOI: 10.55563/clinexprheumatol/ksopba PMID: 41562358

03

Significant reverse association between dietary selenium intake and visceral adiposity in the CODING study.

Yu S, Zhang H, Du J, Sun G

Scientific reports2025Senior author

DOI: 10.1038/s41598-025-29228-3 PMID: 41462524

04

Triglyceride-glucose index and its combination with anthropometric obesity indicators are significant predictors of visceral obesity among the Newfoundland population.

Yu S, Zhang H, Du J, Sun G

Scientific reports2025Senior author

DOI: 10.1038/s41598-025-23439-4 PMID: 41233446

05

Association between dietary selenium intake and the prevalence of prediabetes in Newfoundland population: a cross-sectional study.

Yu S, Zhang H, Du J, Sun G

Frontiers in nutrition2025Senior author

DOI: 10.3389/fnut.2025.1615462 PMID: 40933265

06

Multi-Omics Integrative Analyses Identified Two Endotypes of Hip Osteoarthritis.

Huang J, Liu M, Zhang H, Sun G, Furey A, Rahman P, Zhai G

Metabolites2024

DOI: 10.3390/metabo14090480 PMID: 39330487

07

Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.

Huang Y, Chen L, Li L, Qi Y, Tong H, Wu H, Xu J, Leng L, Cheema S, Sun G, Xia Z, McGuire J, Rodrigues B, Young LH, Bucala R, Qi D

JCI insight2024

DOI: 10.1172/jci.insight.173240 PMID: 38973609

08

Genomic heterozygosity is associated with a lower risk of osteoarthritis.

Gill R, Liu M, Sun G, Furey A, Spector T, Rahman P, Zhai G

BMC genomics2024

DOI: 10.1186/s12864-024-10015-9 PMID: 38245676

09

A pref-1-controlled non-inflammatory mechanism of insulin resistance.

Huang Y, Cui D, Chen L, Tong H, Wu H, Muller GK, Qi Y, Wang S, Xu J, Gao X, Fifield KE, Wang L, Xia Z, Vanderluit JL, Liu S, Leng L, Sun G, McGuire J, Young LH, Bucala R, Qi D

iScience2023

DOI: 10.1016/j.isci.2023.106923 PMID: 37283810

10

Glutathione, polyamine, and lysophosphatidylcholine synthesis pathways are associated with circulating pro-inflammatory cytokines.

Liu M, Zhang H, Xie Z, Huang Y, Sun G, Qi D, Furey A, Randell EW, Rahman P, Zhai G

Metabolomics : Official journal of the Metabolomic Society2022

DOI: 10.1007/s11306-022-01932-5 PMID: 36180605

Refining the molecular endotypes for precision medicine of osteoarthritis

Co-investigatorCIHR2020Project Grant

Principal investigators: Zhai, Guangju

Keywords: Endotypes; Genomics; Metabolomics; Osteoarthritis

$971,550

The link between osteoarthritis and diabetes mellitus

Principal investigatorCIHR2015Operating Grant - PA: IMHA - New Invest.- Musculoskeletal Health Bridge Funding

Principal investigators: Zhai, Guangju; Randell, Edward W; Sun, Guang

Keywords: Advanced-Glycation End-Products; Diabetes Mellitus; Glucose Transporter 1; Metabolic Markers; Methylglyoxal; Osteoarthritis

$100,000

Discovering the neuroendocrine features of obesity with food addiction

SupervisorCIHR2012Master's Award - PA: RPP - Newfoundland and Labrador

Principal investigators: Wadden, Daniel G

Keywords: Appetite Regulation; Diabetes; Dual-Energy X-Ray Absorptiometry; Food Intake; Gut Hormones; Neuropeptides; Obesity; Yale Food Addiction Scale

$8,750

Finding the endocrine and genetic determinants of obesity: The Newfoundland study

Nominated PICIHR2008Operating Grant

Principal investigators: Sun, Guang

Keywords: Cck; Food Intake And Macronutrients; Genetically Homogeneous Newfoundland Population; Ghrelin; Gut Hormones; Ppy And Pyy3-36; Snps; Willett Food Frequency Questionnaire

$806,518

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Genetics
Biomedical Sciences
Community Health
Medicine
Orthopedics
Family Medicine
Surgery
Other

Co-authors at Memorial University of Newfoundland, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Guangju Zhai

Biomedical Sciences

22 shared papers, latest 2026

Jennifer Shea

Community Health

3 shared papers, latest 2013

John McGuire

Department of Medical Biophysics

2 shared papers, latest 2024

Dake Qi

Biomedical Sciences

2 shared papers, latest 2024

Maria Mathews

Community Health

2 shared papers, latest 2008

Shabnam Asghari

Family Medicine

1 shared papers, latest 2018

Konstantin Shestopaloff

Biostatistics Division

1 shared papers, latest 2018

Brian Rodrigues

Cellular and Molecular Pharmacology

1 shared papers, latest 2024

Marshall Godwin

Family Medicine

1 shared papers, latest 2018

Kensuke Hirasawa

Biomedical Sciences

1 shared papers, latest 2016

Arnaud Droit

Microbiologie et immunologie

1 shared papers, latest 2022

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student: Advanced-Glycation End-Products Dear Professor Sun, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Distinct Gut Microbiomic and Metabolomic Signatures in Knee and Hip Osteoarthritis." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Guang Sun

Research

Latest papers

Latest funding

Distinct Gut Microbiomic and Metabolomic Signatures in Knee and Hip Osteoarthritis.

Altered gut microbiota and host pathways in obesity-related knee osteoarthritis.

Significant reverse association between dietary selenium intake and visceral adiposity in the CODING study.

Triglyceride-glucose index and its combination with anthropometric obesity indicators are significant predictors of visceral obesity among the Newfoundland population.

Association between dietary selenium intake and the prevalence of prediabetes in Newfoundland population: a cross-sectional study.

Multi-Omics Integrative Analyses Identified Two Endotypes of Hip Osteoarthritis.

Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia.

Genomic heterozygosity is associated with a lower risk of osteoarthritis.

A pref-1-controlled non-inflammatory mechanism of insulin resistance.

Glutathione, polyamine, and lysophosphatidylcholine synthesis pathways are associated with circulating pro-inflammatory cytokines.

Refining the molecular endotypes for precision medicine of osteoarthritis

The link between osteoarthritis and diabetes mellitus

Discovering the neuroendocrine features of obesity with food addiction

Finding the endocrine and genetic determinants of obesity: The Newfoundland study

Frequent collaborators

Guangju Zhai

Edward Randell

Proton Rahman

Glynn Martin

Dake Qi

Jennifer Shea

John McGuire

Mohit Kapoor

Dake Qi

Johanne Martel-Pelletier

Maria Mathews

Shabnam Asghari

Rajiv Gandhi

Konstantin Shestopaloff

Brian Rodrigues

Hassan Fahmi

Marshall Godwin

Kensuke Hirasawa

Arnaud Droit