Arvind Mer, University of Ottawa

Research

Read how they describe their research on their University of Ottawa profile.

Acute Respiratory Distress Syndrome (Ards)Animal Acute Lung Injury (Ali) Models Artificial Intelligence (Ai)Histological Image Assessment Lung Injury Score

Latest papers

Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity.
Molecular therapy. Oncology · 2026
Probing the Cancer Mutational Landscape of KMT2 Regulatory Subunits.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
Artificial intelligence-enabled histological analysis in pre-clinical respiratory disease models: a scoping review
European Respiratory Review · 2026

All 7 publications

Latest funding

Ethnic and racial disparity in endometriosis pathobiology, diagnosis, and treatment
CIHR · 2024 · Co-investigator
$1,055,700
Machine Learning Framework for Inferring Isoform Functions
NSERC · 2024 · Principal investigator
$44,000
The Canadian Bioinformatics, Computational Biology and Health Data Sciences Training and Community Platform (BCBHDS Platform)
CIHR · 2024 · Co-investigator
$5,550,000

All 5 grants and awards

7 publications.

01

Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity.

St-Denis-Bissonnette F, Mediratta K, Ho N, Kirkby M, Stalker A, Muradia G, Shrestha A, Ardolino M, Lee SH, Burger D, Mer A, Wang L, Lavoie JR

Molecular therapy. Oncology2026

DOI: 10.1016/j.omton.2026.201261 PMID: 42383255

02

Probing the Cancer Mutational Landscape of KMT2 Regulatory Subunits.

Grégoire S, Chow S, Joshi M, Zhang P, Ahmad AA, Janna A, Tremblay V, Muñoz M, Mer A, Couture JF

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2026

DOI: 10.1096/fj.202504644r PMID: 41949561

03

Artificial intelligence-enabled histological analysis in pre-clinical respiratory disease models: a scoping review

Kuhar E, Park J, Jahandideh F, Komeili M, Sadeknury A, Kang N, Karunamurthy P, Zarei MR, Ebrahimi A, Gill SE

European Respiratory Review2026

DOI: 10.1183/16000617.0243-2025

04

Global DNA methylation signatures associated with chemoresistance and poor prognosis of high grade serous ovarian cancer.

Manzoor HB, Acun M, Yasavoli-Sharahi H, Matar C, Mer A, Tsang BK, Asare-Werehene M

Scientific reports2025

DOI: 10.1038/s41598-025-20827-8 PMID: 41125735

05

Spotlight on nuclear PD-L1 in ovarian cancer chemoresistance: hidden but mighty.

Asare-Werehene M, Zaker A, Tripathi S, Communal L, Carmona E, Mes-Masson AM, Tsang BK, Mer A

Frontiers in immunology2025Senior author

DOI: 10.3389/fimmu.2025.1543529 PMID: 40726982

06

Structural insights into an atypical histone binding mechanism by a PHD finger.

Grégoire S, Grégoire J, Yang Y, Capitani S, Joshi M, Sarvan S, Zaker A, Ning Z, Figeys D, Ulrich K, Brunzelle JS, Mer A, Couture JF

Structure (London, England : 1993)2024

DOI: 10.1016/j.str.2024.06.017 PMID: 39029460

07

Large-scale phenogenomic analysis of human cancers uncovers frequent alterations affecting SMC5/6 complex components in breast cancer.

Roy S, Zaker A, Mer A, D'Amours D

NAR cancer2023

DOI: 10.1093/narcan/zcad047 PMID: 37705607

Ethnic and racial disparity in endometriosis pathobiology, diagnosis, and treatment

Co-investigatorCIHR2024Project Grant

Principal investigators: Singh, Sukhbir S; Tsang, Benjamin K

Keywords: Diagnostics; Endometriosis; Endometriotic Lesions; Ethnicity; Immunology; Machine Learning; Personalized Medicine; Proteomics; Race; Whole Genome Sequencing

$1,055,700

Machine Learning Framework for Inferring Isoform Functions

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Mer, Arvind

Keywords: bioinformatics; omics data analysis; machine learning; gene isoforms; alternative splicing; isoforms function; functional annotation; pathway analysis; rna splicing; deep learning

$44,000

The Canadian Bioinformatics, Computational Biology and Health Data Sciences Training and Community Platform (BCBHDS Platform)

Co-investigatorCIHR2024Training Grant: HRTP - Bioinformatics, Computational Biology, Health Data Scien.

Principal investigators: Brazas, Michelle D; Bourque, Guillaume; Hsiao, William; Hughes, Nia; Hussin, Julie; Kong, Jude D; Pai, Shraddha; Sukhai, Mahadeo; Wasserman, Wyeth W; Wishart, David S

Keywords: Bioinformatics, Computational Biology & Health Data Science; Championing Diverse Talent And Careers; Competency Based Learning Pathways; Graduates, Post-Graduates And Early Career Researchers; Idea- And Career-Focused Matched Mentorship Guidance; Interdisciplinary, Intersectoral Capacity Building; Local Training Opportunities And Awards; National Community Building Activities; On-Demand, Virtual And In-Person Training; Professional Development Training

$5,550,000

Accelerating and standardizing assessment of acute lung injury using an artificial intelligence based approach

Nominated PICIHR2024Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Mer, Arvind; Lalu, Manoj M; Liaw, Patricia C

Keywords: Acute Respiratory Distress Syndrome (Ards); Animal Acute Lung Injury (Ali) Models; Artificial Intelligence (Ai); Histological Image Assessment; Lung Injury Score

$100,000

Machine Learning Framework for Inferring Isoform Functions

Principal investigatorNSERC2024Discovery Launch Supplement

Principal investigators: Mer, Arvind

Keywords: bioinformatics; omics data analysis; machine learning; gene isoforms; alternative splicing; isoforms function; functional annotation; pathway analysis; rna splicing; deep learning

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biochemistry, Microbiology and Immunology
Cellular and Molecular Medicine
Nutrition Sciences
Medicine

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Jean-François Couture

Biochemistry, Microbiology and Immunology

2 shared papers, latest 2026

Seung-Hwan Lee

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2026

Daniel Figeys

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2024

Chantal Matar

Nutrition Sciences

1 shared papers, latest 2025

Dylan Burger

Cellular and Molecular Medicine

1 shared papers, latest 2026

Michele Ardolino

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2026

Damien D'Amours

Cellular and Molecular Medicine

1 shared papers, latest 2023

Patricia Chia-Ying Liaw

Medicine

1 shared papers, latest 2026

Lisheng Wang

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2024

Subject: Prospective PhD student: Acute Respiratory Distress Syndrome (Ards) Dear Professor Mer, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Machine Learning Framework for Inferring Isoform Functions" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]