Jing Wang, University of Ottawa

Research

Read how they describe their research on their University of Ottawa profile.

Monoacylglycerol Lipase Neuronal Differentiation Cognition 2-Ag/Endocannabinoid Receptor Signaling Hypothalamic Arcuate Nucleus Neural Circuitry Odor-Reward Associative Memory Olfactory Bulb Neurogenesis

Latest papers

Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion.
Nature neuroscience · 2026
Prenatal low-dose MeHg exposure leads to proteomic and transcriptomic alterations consistent with neurodegenerative disease in the cerebellum of C57BL/6 mice.
The Journal of toxicological sciences · 2026
Author Correction: Aldehydic load as an objective imaging biomarker of mild traumatic brain injury.
Npj imaging · 2025

All 28 publications

Latest funding

Monoacylglycerol lipase (Mgll)-regulated 2-AG/eCBR signaling in feeding circuits controls adult neurogenesis
CIHR · 2025 · Nominated PI
$1,309,680
Prenatal exposure of low-dose methylmercury causes abnormal neurodevelopment and its underlying mechanisms
CIHR · 2024 · Nominated PI
$1,151,326
Neuronal regulation of subventricular zone adult neural stem cell function and olfactory bulb neurogenesis
NSERC · 2023 · Principal investigator
$90,000

All 7 grants and awards

28 publications.

01

Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion.

Kukreja B, Jeon S, Cao W, Rusu B, Harrison CF, Ghazisaeidi S, Tahmasian N, Feng MY, Chan R, Loan A, Johnston WB, Padhy S, Rakoff-Nahoum S, Wang J, Yim YS, Kalish BT

Nature neuroscience2026

DOI: 10.1038/s41593-025-02162-3 PMID: 41495254

02

Prenatal low-dose MeHg exposure leads to proteomic and transcriptomic alterations consistent with neurodegenerative disease in the cerebellum of C57BL/6 mice.

Loan A, D'Mello R, Li Y, Nurkan T, Minic Z, Wang J, Man Chan H

The Journal of toxicological sciences2026

DOI: 10.2131/jts.51.89 PMID: 41621861

03

Author Correction: Aldehydic load as an objective imaging biomarker of mild traumatic brain injury.

Kirby A, Ward C, Goulet CS, Calvert ND, Daniel R, Leung JW, Sharma A, Suchý M, Donatelli C, Wang J, Standen E, Shuhendler AJ

Npj imaging2025

DOI: 10.1038/s44303-025-00114-x PMID: 41053357

04

Aldehydic load as an objective imaging biomarker of mild traumatic brain injury.

Kirby A, Ward C, Goulet CS, Calvert ND, Daniel R, Leung JW, Sharma A, Suchý M, Donatelli C, Wang J, Standen E, Shuhendler AJ

Npj imaging2025

DOI: 10.1038/s44303-025-00096-w PMID: 40604170

05

Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms.

Loan A, Awaja N, Lui M, Syal C, Sun Y, Sarma SN, Chona R, Johnston WB, Cordova A, Saraf D, Nakhlé A, O'Connor K, Thomas J, Leung J, Seegobin M, He L, Wondisford FE, Picketts DJ, Tsai EC, Chan HM, Wang J

Theranostics2024Senior author

DOI: 10.7150/thno.97165 PMID: 39431007

06

Reduction of Glyoxalase 1 Expression Links Fetal Methylmercury Exposure to Autism Spectrum Disorder Pathogenesis.

Leung JW, Loan A, Xu Y, Yang G, Wang J, Chan HM

Toxics2024

DOI: 10.3390/toxics12070449 PMID: 39058101

07

Assessing multimodal emotion recognition in multiple sclerosis with a clinically accessible measure.

Pumphrey JD, Ramani S, Islam T, Berard JA, Seegobin M, Lymer JM, Freedman MS, Wang J, Walker LAS

Multiple sclerosis and related disorders2024

DOI: 10.1016/j.msard.2024.105603 PMID: 38583368

08

Promising use of metformin in treating neurological disorders: biomarker-guided therapies.

Loan A, Syal C, Lui M, He L, Wang J

Neural regeneration research2024Senior author

DOI: 10.4103/1673-5374.385286 PMID: 37862207

09

Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model.

Loan A, Leung JW, Cook DP, Ko C, Vanderhyden BC, Wang J, Chan HM

iScience2023

DOI: 10.1016/j.isci.2023.106093 PMID: 36843845

10

Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer's disease.

Liu Y, Bilen M, McNicoll MM, Harris RA, Fong BC, Iqbal MA, Paul S, Mayne J, Walker K, Wang J, Figeys D, Slack RS

Cell death & disease2023

DOI: 10.1038/s41419-023-05650-1 PMID: 36801910

Monoacylglycerol lipase (Mgll)-regulated 2-AG/eCBR signaling in feeding circuits controls adult neurogenesis

Nominated PICIHR2025Project Grant

Principal investigators: Wang, Jing

Keywords: 2-Ag/Endocannabinoid Receptor Signaling; Hypothalamic Arcuate Nucleus; Monoacylglycerol Lipase; Neural Circuitry; Neuronal Differentiation; Odor-Reward Associative Memory; Olfactory Bulb Neurogenesis; Pomc Satiety Activating Neurons; Svz Neural Stem/Precursor Cell

$1,309,680

Prenatal exposure of low-dose methylmercury causes abnormal neurodevelopment and its underlying mechanisms

Nominated PICIHR2024Project Grant

Principal investigators: Wang, Jing; Chan, Laurie H

Keywords: Brain Organoids; Cognition; Cortical Precursors; Creb Activity; Embryonic Cerebral Cortex Development; Glyoxalase 1; Human Ipsc; Neurodevelopmental Disorder; Neuronal Differentiation; Proliferation

$1,151,326

Neuronal regulation of subventricular zone adult neural stem cell function and olfactory bulb neurogenesis

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Wang, Jing

Keywords: adult neural stem/progenitor cells; chemogenetic approach; neuronal activity; olfactory bulb neurogenesis; olfactory function; proliferation; rabies virus tracing; regionalization; subventricular zone

$90,000

A clinically-applicable biomaterial-guided local drug delivery system to promote post-stroke brain regeneration and functional recovery

Principal investigatorSSHRC2020New Frontiers in Research Fund - Exploration

Principal investigators: Wang, Jing

$250,000

Optimizing cell-based therapies to promote neurovascular regeneration and behavioural recovery after ischemic stroke

Nominated PICIHR2019Project Grant

Principal investigators: Wang, Jing; Brand, Marjorie C

Keywords: Cell Transplantation; Enriched Rehabilitation; Focal Ischemic Stroke; Human Endothelial Progenitors; Human Ipsc-Derived Neural Stem Cell; Preconditioning; Regeneration; Stroke Motor Recovery

$780,300

Understanding molecular control of lipid metabolism in brain aging

Nominated PICIHR2017Project Grant

Principal investigators: Wang, Jing

Keywords: Brain Aging; Cognition; Creb Binding Protein Phosphorylation; Endocannobinoid Signaling; Epigentic Regulation; Lipid Metablism; Monoacylglycerol Lipase; Neural Stem/Precursor Cell Fate; Neurogensis

$726,751

Epigenetic Regulation of Adult Hippocampal Neurogenesis

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Wang, Jing

$217,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Cellular and Molecular Medicine
Medical Genetics
Biochemistry, Microbiology and Immunology
Ophthalmology
Department of Medicine
Medicine/Neurology
Neurosciences
Other

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Diane Lagace

Cellular and Molecular Medicine

3 shared papers, latest 2022

Baptiste Lacoste

Cellular and Molecular Medicine

2 shared papers, latest 2022

Anastassia Voronova

Medical Genetics

1 shared papers, latest 2023

Guang Yang

Medical Genetics

1 shared papers, latest 2024

Simonetta Sipione

Pharmacology

1 shared papers, latest 2023

Fabrizio Giuliani

Medicine/Neurology

1 shared papers, latest 2023

Curtis Cooper

Department of Medicine

1 shared papers, latest 2015

Steffany Bennett

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2016

Daniel Figeys

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2023

Catherine Tsilfidis

Ophthalmology

1 shared papers, latest 2022

Karl Fernandes

Neurosciences

1 shared papers, latest 2020

Dale Corbett

Cellular and Molecular Medicine

1 shared papers, latest 2018

Martin Parent

Psychiatrie et de neurosciences

1 shared papers, latest 2020

Rashmi Kothary

Cellular and Molecular Medicine

1 shared papers, latest 2020

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Monoacylglycerol Lipase Dear Professor Wang, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Monoacylglycerol lipase (Mgll)-regulated 2-AG/eCBR signaling in feeding circuits controls adult neurogenesis" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]