Faculty profile

Rashmi Kothary

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Full ProfessorCellular and Molecular MedicineUniversity of Ottawa

Rashmi Kothary

Full Professor

Cellular and Molecular Medicine

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
30 publications in the last five years, latest in 2026.
Senior (last) author on 12 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (13 CIHR), most recently in 2023.
Supervised 14 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

125

Publications

250

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Spinal Muscular Atrophy Mouse Models Clinical Trial Networks Networks Neuromuscular Disease Open Science Patient Partnerships Preclinical Research Resources

Latest papers

2nd NMD4C basic research summer school on promoting standardized protocols to advance translational research in neuromuscular disorders.
Journal of neuromuscular diseases · 2026
Multiple spinal muscular atrophy disease-modifying effects of a Hspa8G470R synaptic chaperone variant.
Brain : a journal of neurology · 2026
Extracellular vesicles as biomarkers of disease progression and therapeutic response in patients with spinal muscular atrophy.
Molecular therapy. Advances · 2026

All 125 publications

Latest funding

Development of Combinatorial Therapy for the Treatment of Spinal Muscular Atrophy
CIHR · 2025 · Supervisor
$120,000
NMD4C: the neuromuscular network for Canada
CIHR · 2023 · Principal investigator
$1,000,000
6th Ottawa International Conference on Neuromuscular Disease and Biology
CIHR · 2023 · Co-investigator
$15,000

All 34 grants and awards

125 publications.

2nd NMD4C basic research summer school on promoting standardized protocols to advance translational research in neuromuscular disorders.

Rihoux A, Sutton E, Lee J, Flewwelling L, Garibotti M, Osman H, Cheng A, Scimè A, G R Perry C, Patten K, Chang N, Kothary R, Leduc-Gaudet JP

Journal of neuromuscular diseases2026

DOI: 10.1177/22143602251408154 PMID: 41417778

Multiple spinal muscular atrophy disease-modifying effects of a Hspa8G470R synaptic chaperone variant.

Her YR, Fuentes-Moliz A, Kothary R, Tabares L, Monani UR

Brain : a journal of neurology2026

DOI: 10.1093/brain/awag224 PMID: 42343572

Extracellular vesicles as biomarkers of disease progression and therapeutic response in patients with spinal muscular atrophy.

Poulin KL, René CA, Smith IC, Vacratsis PO, Burger D, McMillan HJ, Kothary R, Perkins TJ, Warman-Chardon J, Parks RJ

Molecular therapy. Advances2026

DOI: 10.1016/j.omta.2026.201757 PMID: 42232219

Cardiac defects in spinal muscular atrophy and the role of SMN in cardiomyocyte homeostasis.

Garner R, Ha LL, Nery FC, Spellman RG, Chehade L, Eichelberger EJ, Da Silva Duarte Lepez S, Johnstone AJ, Kothary R, Swoboda KJ, Alves CRR

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.03.20.713246 PMID: 41928955

Maternal-Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy.

Sutton ER, Beauvais A, Yaworski R, McMillan HJ, Kothary R

Annals of neurology2026Senior author

DOI: 10.1002/ana.78302 PMID: 42458739

Report on the 7th Ottawa International Conference on Neuromuscular Disease & Biology - September 11-13, 2025, Ottawa, Canada.

Warman-Chardon J, Jasmin BJ, Kothary R, Parks RJ

Journal of neuromuscular diseases2026

DOI: 10.1177/22143602261481647 PMID: 42743587

Report on the 6th Ottawa International Conference on Neuromuscular Disease & Biology - September 7-9, 2023, Ottawa, Canada.

Warman-Chardon J, Jasmin BJ, Kothary R, Parks RJ

Journal of neuromuscular diseases2025

DOI: 10.1177/22143602241304993 PMID: 39973448

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology.

de Almeida MMA, De Repentigny Y, Gagnon S, Sutton ER, Kothary R

eLife2025Senior author

DOI: 10.7554/elife.99141 PMID: 39976226

The systemic complexity of a monogenic disease: the molecular network of spinal muscular atrophy.

Tapken I, Schweitzer T, Paganin M, Schüning T, Detering NT, Sharma G, Niesert M, Saffari A, Kuhn D, Glynn A, Cieri F, Santonicola P, Cannet C, Gerstner F, Faller KME, Huang YT, Kothary R, Gillingwater TH, Di Schiavi E, Simon CM, Hensel N, Ziegler A, Viero G, Pich A, Claus P

Brain : a journal of neurology2025

DOI: 10.1093/brain/awae272 PMID: 39183150

Skeletal Muscle Mitochondrial and Autophagic Dysregulation Are Modifiable in Spinal Muscular Atrophy.

Mikhail AI, Ng SY, Xhuti D, Lesinski MA, Chhor J, Deguise MO, De Repentigny Y, Nederveen JP, Kothary R, Tarnopolsky MA, Ljubicic V

Journal of cachexia, sarcopenia and muscle2025

DOI: 10.1002/jcsm.13701 PMID: 39901351

Development of Combinatorial Therapy for the Treatment of Spinal Muscular Atrophy

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Yaworski, Rebecca A

Keywords: Electrophysiology, Compound Muscle Action Potential; Evaluation Of Combinatorial Therapy In A Mouse Model Of Sma; Gene Replacement Therapy, Dose Escalation Study; In Vivo Testing Of Crispr Base Editor; International Collaboration, Canada And Usa; Motor Function Testing, Righting Reflex, Gait Analysis; Novel Therapy For The Treatment Of Spinal Muscular Atrophy; Phenotypic Analysis, Histopathology, Fluorescent Microscopy; Regenerative Medicine, Pediatric Neuromuscular Disorder; Translational Research

$120,000

NMD4C: the neuromuscular network for Canada

Principal investigatorCIHR2023Network Gr. in Skin Health, Bone Health, and Muscular Dyst. - Muscular Dystrophy

Principal investigators: Lochmüller, Hanns; Osman, Homira; Brais, Bernard; Campbell, Craig Gordon N; Chang, Natasha C; Dowling, James; Gagnon, Cynthia; Gonorazky, Hernan D; Hodgkinson, Victoria; Karamchandani, Jason; Korngut, Lawrence W; Kothary, Rashmi K; Mah, Jean K; O'Connell, Colleen; Patten, Kessen; Rossi, Fabio M; Schellenberg, Kerri; Selby, Kathryn A; Warman Chardon, Jodi

Keywords: Clinical Trial Networks; Networks; Neuromuscular Disease; Open Science; Patient Partnerships; Preclinical Research Resources; Training And Education; Translational Research

$1,000,000

6th Ottawa International Conference on Neuromuscular Disease and Biology

Co-investigatorCIHR2023Planning and Dissemination Grant - Institute Community Support

Principal investigators: Parks, Robin J

Keywords: Als; Conference; Dystrophinopathies; Genetic Disease; Motor Neuron; Muscle; Myopathies; Neuromuscular; Neuropathies; Stem Cells

$15,000

Extra-neuronal contribution to spinal muscular atrophy disease pathogenesis

Nominated PICIHR2022Project Grant

Principal investigators: Kothary, Rashmi K

Keywords: Aav Gene Therapy; Fatty Liver; Igf1; Lipid Metabolism; Nafld; Neuromuscular; Spinal Muscular Atrophy

$818,550

Extracellular vesicles as a biomarker and therapeutic for Spinal Muscular Atrophy

Co-investigatorCIHR2021Project Grant

Principal investigators: Parks, Robin J

Keywords: Biomarkers; Extracellular Vesicles; Gene Therapy; Spinal Muscular Atrophy

$960,076

Investigating liver intrinsic defects in Spinal Muscular Atrophy

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Reilly, Aoife

Keywords: Animal Models; Liver; Nafld; Neurodegeneration; Spinal Muscular Atrophy; Transcriptomics

$105,000

Extracellular vesicles as a biomarker and therapeutic for Spinal Muscular Atrophy

Co-investigatorCIHR2020Project Grant - PA: Musculoskeletal Health and Arthritis - Pain

Principal investigators: Parks, Robin J

Keywords: Biomarkers; Extracellular Vesicles; Gene Therapy; Spinal Muscular Atrophy

$100,000

Effect of T regulatory cell transplant in demyelinating disease; using the visual system as a model to study potential remyelinating and neuroprotective therapies for multiple sclerosis.

SupervisorCIHR2019Canada Graduate Scholarships - Michael Smith Foreign Study Supplements

Principal investigators: Beaudry-Richard, Alexandra

Keywords: Cellules T Régulatrices (Tregs); Inflammation; Myélinisation; Potentiel Évoqué Visuel; Rétine; Sclérose En Plaques; Souris Transgénique; Système Immunitaire; Tomographie Par Cohérence Optique; Transplantation

$6,000

NMD4C: An integrated research network for patients, scientists, and clinicians to improve outcomes and access to therapies for patients with neuromuscular disorders in Canada.

Co-investigatorCIHR2019Network Catalyst Grants - Muscular Dystrophy

Principal investigators: Lochmüller, Hanns; Buffone, Teresa; Dowling, James; Warman Chardon, Jodi

Keywords: Genomics; Knowledge Translation; Networks; Neuromuscular Disease; Patient Engagement; Translational Research

$599,992

5th Ottawa International Conference on Neuromuscular Disease and Biology

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Parks, Robin J

Keywords: Als; Conference; Dystrophinopathies; Motor Neuron; Muscle; Myopathies; Neuromuscular; Neuron; Neuropathies; Stem Cells

$20,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Rashmi Kothary

Research

Latest papers

Latest funding

2nd NMD4C basic research summer school on promoting standardized protocols to advance translational research in neuromuscular disorders.

Multiple spinal muscular atrophy disease-modifying effects of a Hspa8G470R synaptic chaperone variant.

Extracellular vesicles as biomarkers of disease progression and therapeutic response in patients with spinal muscular atrophy.

Cardiac defects in spinal muscular atrophy and the role of SMN in cardiomyocyte homeostasis.

Maternal-Fetal Administration of Risdiplam Partially Rescues the SMN&#x394;7 Mouse Model of Spinal Muscular Atrophy.

Report on the 7th Ottawa International Conference on Neuromuscular Disease & Biology - September 11-13, 2025, Ottawa, Canada.

Report on the 6th Ottawa International Conference on Neuromuscular Disease & Biology - September 7-9, 2023, Ottawa, Canada.

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology.

The systemic complexity of a monogenic disease: the molecular network of spinal muscular atrophy.

Skeletal Muscle Mitochondrial and Autophagic Dysregulation Are Modifiable in Spinal Muscular Atrophy.

Frequent collaborators

Jodi Warman Chardon

Kunal Bhanot

Jean Michaud

Jean-Marc Renaud

Alexandre Blais

Catherine Tsilfidis

Ilya Ioshikhes

Dylan Burger

Antonio Giulivi

Daniel Figeys

Xiaohui Zha

John Woulfe

Jing Wang

Mary-Ellen Harper

Natasha Chang

Anne-Claude Gingras

Homira Osman

David Lohnes

Benoit Chabot

Lincoln Stein

Marc Ekker

Diane Lagace

Alain Stintzi

Carol Schuurmans

Maternal-Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy.