Faculty profile

Jim Dimitroulakos

ResearcherCancer TherapeuticsUniversity of Ottawa

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Ottawa directory, so their courses and email address may be missing. Find their university profile.

Jim Dimitroulakos

Researcher

Cancer Therapeutics

Health Sciences

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
No publications since 2020.
Principal investigator on 2 research grants (2 CIHR), most recently in 2013.
Supervised 1 trainee who won CIHR awards, most recently in 2008.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Cell Signaling Experimental Therapeutics Geranylgeranyled Proteins Mevalonate Pathway Metabolic Stress Pathways Platins

Latest papers

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells.
International journal of molecular sciences · 2020
C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2019
Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening.
Advanced materials (Deerfield Beach, Fla.) · 2019

All 37 publications

Latest funding

MicroRNA signature in chemoprevention of mammary carcinoma by probiotics through control of cancer stem cells.
CIHR · 2014 · Co-investigator
$100,000
Targeting the mevalonate pathway in novel combination based therapeutic approaches
CIHR · 2013 · Nominated PI
$349,842
The cellular stress response regulator ATF3 is a novel mediator of platin induced tumour cell cytotoxicity and resistance
CIHR · 2012 · Nominated PI
$100,000

All 4 grants and awards

37 publications.

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells.

Sulaiman A, McGarry S, Chambers J, Al-Kadi E, Phan A, Li L, Mediratta K, Dimitroulakos J, Addison C, Li X, Wang L

International journal of molecular sciences2020

DOI: 10.3390/ijms21165788 PMID: 32806648

C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer.

Johnson-Obaseki S, Caulley L, Corsten M, Liu G, Dimitroulakos J, Goldstein D, Irish J, Rider J

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2019

DOI: 10.1177/0194599818800297 PMID: 30226795

Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening.

Tam RY, Yockell-Lelièvre J, Smith LJ, Julian LM, Baker AEG, Choey C, Hasim MS, Dimitroulakos J, Stanford WL, Shoichet MS

Advanced materials (Deerfield Beach, Fla.)2019

DOI: 10.1002/adma.201806214 PMID: 30589121

Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer.

Hasim MS, Nessim C, Villeneuve PJ, Vanderhyden BC, Dimitroulakos J

Translational oncology2018Senior author

DOI: 10.1016/j.tranon.2018.06.001 PMID: 29940414

Effect of statin use on oncologic outcomes in head and neck squamous cell carcinoma.

Lebo NL, Griffiths R, Hall S, Dimitroulakos J, Johnson-Obaseki S

Head & neck2018

DOI: 10.1002/hed.25152 PMID: 29934959

Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.

Sulaiman A, McGarry S, Lam KM, El-Sahli S, Chambers J, Kaczmarek S, Li L, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Liu S, Xie Y, Gadde S, Li X, Wang L

Cell death & disease2018

DOI: 10.1038/s41419-018-0811-7 PMID: 30050079

Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states.

Sulaiman A, McGarry S, Li L, Jia D, Ooi S, Addison C, Dimitroulakos J, Arnaout A, Nessim C, Yao Z, Ji G, Song H, Gadde S, Li X, Wang L

Molecular oncology2018

DOI: 10.1002/1878-0261.12167 PMID: 29316250

Does metformin usage improve survival in head and neck squamous cell carcinoma? A population-based study.

Quimby AE, Lebo NL, Griffiths R, Hall S, Dimitroulakos J, Johnson-Obaseki S

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2018

DOI: 10.1186/s40463-018-0322-7 PMID: 30514404

Correction to: HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours.

Wasserman JK, Rourke R, Purgina B, Caulley L, Dimitroulakos J, Corsten M, Johnson-Obaseki S

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2018

DOI: 10.1186/s40463-018-0294-7 PMID: 30071890

Human papillomavirus: An unlikely etiologic factor in sinonasal inverted papilloma

Mohajeri S, Lai C, Purgina B, Almutairi D, Baghai T, Dimitroulakos J, Kilty S

The Laryngoscope201834 citations

DOI: 10.1002/lary.27207

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Jim Dimitroulakos

Research

Latest papers

Latest funding

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells.

C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer.

Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening.

Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer.

Effect of statin use on oncologic outcomes in head and neck squamous cell carcinoma.

Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.

Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states.

Does metformin usage improve survival in head and neck squamous cell carcinoma? A population-based study.

Correction to: HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours.

Human papillomavirus: An unlikely etiologic factor in sinonasal inverted papilloma

MicroRNA signature in chemoprevention of mammary carcinoma by probiotics through control of cancer stem cells.

Targeting the mevalonate pathway in novel combination based therapeutic approaches

The cellular stress response regulator ATF3 is a novel mediator of platin induced tumour cell cytotoxicity and resistance

Preclinical/clinical evaluation of a CDK4/6 inhibitor + 5-FU in colon cancer

Frequent collaborators

Lisheng Wang

Christina Addison

Angel Arnaout

Glenwood Goss

Suresh Gadde

Ryan Rourke

Zemin Yao

Lesley Seymour

Bryan Lo

Louise Pilote

Lauralyn McIntyre

Louise Pilote

Jonathan Irish

Shaun Kilty

Rebecca Auer

Yonghong Wan

Brian Lichty

Sepideh Mohajeri

Jean-Simon Diallo

Geoffrey Liu

Jim Dimitroulakos

Research

Latest papers

Latest funding

Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells.

C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer.

Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening.

Activating Transcription Factor 3 as a Novel Regulator of Chemotherapy Response in Breast Cancer.

Effect of statin use on oncologic outcomes in head and neck squamous cell carcinoma.

Co-inhibition of mTORC1, HDAC and ESR1&#x3b1; retards the growth of triple-negative breast cancer and suppresses cancer stem cells.

Dual inhibition of Wnt and Yes-associated protein signaling retards the growth of triple-negative breast cancer in both mesenchymal and epithelial states.

Does metformin usage improve survival in head and neck squamous cell carcinoma? A population-based study.

Correction to: HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours.

Human papillomavirus: An unlikely etiologic factor in sinonasal inverted papilloma

MicroRNA signature in chemoprevention of mammary carcinoma by probiotics through control of cancer stem cells.

Targeting the mevalonate pathway in novel combination based therapeutic approaches

The cellular stress response regulator ATF3 is a novel mediator of platin induced tumour cell cytotoxicity and resistance

Preclinical/clinical evaluation of a CDK4/6 inhibitor + 5-FU in colon cancer

Frequent collaborators

Lisheng Wang

Christina Addison

Angel Arnaout

Glenwood Goss

Suresh Gadde

Ryan Rourke

Zemin Yao

Lesley Seymour

Bryan Lo

Louise Pilote

Lauralyn McIntyre

Louise Pilote

Jonathan Irish

Shaun Kilty

Rebecca Auer

Yonghong Wan

Brian Lichty

Sepideh Mohajeri

Jean-Simon Diallo

Geoffrey Liu

Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.