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Suresh Gadde

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Assistant ProfessorBiochemistry, Microbiology and ImmunologyUniversity of Ottawa

Suresh Gadde

Assistant Professor

Biochemistry, Microbiology and Immunology

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
9 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Research

Read how they describe their research on their University of Ottawa profile.

Atherosclerosis Micrornas Nanomedicines Targeted Nanoparticles Antimicrobial Peptide Contraceptive Hiv Ll-37

Latest papers

Unveiling the Light Induced Energy Transfer Events in Water Soluble Benzothiazole Appended Borondipyrromethene: Synthesis, Photophysical Study, and Applications to Amyloid Binding.
Chemistry, an Asian journal · 2026
Nanoparticle-delivered miR-486-5p inhibits H2O2-induced injury in cultured endothelial and kidney tubular epithelial cells.
Nanoscale advances · 2026 · senior author
Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7.
Molecular therapy. Nucleic acids · 2025

All 20 publications

Latest funding

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles
NSERC · 2024 · Co-investigator
$150,000
INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)
NSERC · 2022 · Co-investigator
$733,440
miRNA-based targeted nanotherapies for atherosclerosis
CIHR · 2022 · Nominated PI
$837,675

All 7 grants and awards

20 publications.

Unveiling the Light Induced Energy Transfer Events in Water Soluble Benzothiazole Appended Borondipyrromethene: Synthesis, Photophysical Study, and Applications to Amyloid Binding.

Bandi S, Rathnayaka R, Rana M, Sangolkar AA, Fawaz G, Gahunia E, Courtemanche A, Boligorla A, Pawar R, Sharma AK, Gadde S, D'Souza F, Chitta R

Chemistry, an Asian journal2026

DOI: 10.1002/asia.70372 PMID: 41082675

Nanoparticle-delivered miR-486-5p inhibits H2O2-induced injury in cultured endothelial and kidney tubular epithelial cells.

Maadelat AO, Wehella S, Douvris A, Manturthi S, Burns KD, Gadde S

Nanoscale advances2026Senior author

DOI: 10.1039/d5na00581g PMID: 41404475

Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7.

Singh D, Kushwaha T, Kulandaisamy R, Kumar V, Baswal K, Tiwari SH, Ghorai A, Kumar M, Kumar S, De S, Polamarasetty A, Sehgal D, Katika MR, Gadde S, Côté M, Kayampeta SR, Appaiahgari MB, Inampudi KK

Molecular therapy. Nucleic acids2025

DOI: 10.1016/j.omtn.2025.102452 PMID: 39944792

Nanoparticle-Mediated mRNA Delivery to Triple-Negative Breast Cancer (TNBC) Patient-Derived Xenograft (PDX) Tumors.

El-Sahli S, Manturthi S, Durocher E, Bo Y, Akman A, Sannan C, Kirkby M, Iroakazi CD, Deyell H, Kaczmarek S, Lee SH, Iqbal U, Côté M, Wang L, Gadde S

ACS pharmacology & translational science2025Senior author

DOI: 10.1021/acsptsci.4c00597 PMID: 39974646

VAC14 oligomerization is essential for the function of the FAB1/PIKfyve-VAC14-FIG4 complex.

Zhang L, Uygun T, Hahn HJ, Liu Y, Rivero-Ríos P, Li D, Navratna V, Bristow E, Luo G, Kovarzin A, Bo Y, Gadde S, Côté M, Ko DC, Mosalaganti S, Reinisch KM, Weisman LS

Molecular biology of the cell2025

DOI: 10.1091/mbc.e24-11-0490 PMID: 40305106

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression

Jo D-H, Kaczmarek S, Khan AUH, Pervin J, Clark DM, Gadde S, Wang L, McComb S, Visram A, Lee S-H

Frontiers in Immunology202516 citations

DOI: 10.3389/fimmu.2025.1533044

Nanoparticles Codelivering mRNA and SiRNA for Simultaneous Restoration and Silencing of Gene/Protein Expression In Vitro and In Vivo.

Manturthi S, El-Sahli S, Bo Y, Durocher E, Kirkby M, Popatia A, Mediratta K, Daniel R, Lee SH, Iqbal U, Côté M, Wang L, Gadde S

ACS nanoscience Au2024Senior author

DOI: 10.1021/acsnanoscienceau.4c00040 PMID: 39713729

Development of Pro-resolving and Pro-efferocytic Nanoparticles for Atherosclerosis Therapy.

Patel Y, Manturthi S, Tiwari S, Gahunia E, Courtemanche A, Gandelman M, Côté M, Gadde S

ACS pharmacology & translational science2024Senior author

DOI: 10.1021/acsptsci.4c00292 PMID: 39416959

Plasminogen Activator Inhibitor-1-Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype.

Jung RG, Duchez AC, Simard T, Dhaliwal S, Gillmore T, Di Santo P, Labinaz A, Ramirez FD, Rasheed A, Robichaud S, Ouimet M, Short S, Clifford C, Xiao F, Lordkipanidzé M, Burger D, Gadde S, Rayner KJ, Hibbert B

JACC. Basic to translational science2022

DOI: 10.1016/j.jacbts.2022.05.002 PMID: 36337926

A triple-drug nanotherapy to target breast cancer cells, cancer stem cells, and tumor vasculature.

El-Sahli S, Hua K, Sulaiman A, Chambers J, Li L, Farah E, McGarry S, Liu D, Zheng P, Lee SH, Cui J, Ekker M, Côté M, Alain T, Li X, D'Costa VM, Wang L, Gadde S

Cell death & disease2021Senior author

DOI: 10.1038/s41419-020-03308-w PMID: 33414428

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Gibbings, Derrick

Keywords: cell biology; drug delivery; endosomes; exosomes; extracellular vesicles; lipid nanoparticles; nanoparticles; Nanoparticle tracking; particle heterogeneity and subpopulations

$150,000

INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)

Co-investigatorNSERC2022Collaborative Research and Training Experience

Principal investigators: Alarcon, Emilio

$733,440

miRNA-based targeted nanotherapies for atherosclerosis

Nominated PICIHR2022Project Grant

Principal investigators: Gadde, Suresh

Keywords: Atherosclerosis; Micrornas; Nanomedicines; Targeted Nanoparticles

$837,675

Designing novel multifunctional nanosystems to improve intracellular delivery

Principal investigatorNSERC2022Discovery Launch Supplement

Principal investigators: Gadde, Suresh

$12,500

Designing novel multifunctional nanosystems to improve intracellular delivery

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Gadde, Suresh

$87,000

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)

Principal investigatorCIHR2020Project Grant

Principal investigators: Tanphaichitr, Nongnuj; Angel, Jonathan B; Gadde, Suresh; Sheth, Prameet M

Keywords: Antimicrobial Peptide; Contraceptive; Hiv; Ll-37; Microbicide; Nanoparticle; Neisseria Gonorrhoeae; Spermicide; Vagina; Vaginal Microbiome

$734,400

A new strategy capable of directly killing cancer cells and concurrently boosting anti-tumor immunity for the effective treatment of TNBC

Principal investigatorCIHR2020Project Grant

Principal investigators: Wang, Lisheng; Gadde, Suresh

Keywords: Anti-Cancer Immunity; Cancer Stem Cells; Chemotherapeutic Drug; Mouse Model; Nanotherapeutics,; Patient-Derived Xenograft; Triple Negative Breast Cancer; Wnt; Yap/Mevalonate Pathway

$837,675

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Suresh Gadde

Research

Latest papers

Latest funding

Unveiling the Light Induced Energy Transfer Events in Water Soluble Benzothiazole Appended Borondipyrromethene: Synthesis, Photophysical Study, and Applications to Amyloid Binding.

Nanoparticle-delivered miR-486-5p inhibits H2O2-induced injury in cultured endothelial and kidney tubular epithelial cells.

Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7.

Nanoparticle-Mediated mRNA Delivery to Triple-Negative Breast Cancer (TNBC) Patient-Derived Xenograft (PDX) Tumors.

VAC14 oligomerization is essential for the function of the FAB1/PIKfyve-VAC14-FIG4 complex.

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression

Nanoparticles Codelivering mRNA and SiRNA for Simultaneous Restoration and Silencing of Gene/Protein Expression In Vitro and In Vivo.

Development of Pro-resolving and Pro-efferocytic Nanoparticles for Atherosclerosis Therapy.

Plasminogen Activator Inhibitor-1-Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype.

A triple-drug nanotherapy to target breast cancer cells, cancer stem cells, and tumor vasculature.

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles

INterdisciplinary Training in BIOmedical TECHnologies (INTBIOTECH)

miRNA-based targeted nanotherapies for atherosclerosis

Designing novel multifunctional nanosystems to improve intracellular delivery

Designing novel multifunctional nanosystems to improve intracellular delivery

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)

A new strategy capable of directly killing cancer cells and concurrently boosting anti-tumor immunity for the effective treatment of TNBC

Frequent collaborators

Lisheng Wang

Seung-Hwan Lee

Zemin Yao

Angel Arnaout

Christina Addison

Jim Dimitroulakos

Mireille Ouimet

Tommy Alain

Benjamin Hibbert

David Allan

Anton Zilman

Marc Ekker

Daniel Figeys

Alissa Visram

Dylan Burger

Marceline Côté