Faculty profile

Jean-Pierre Routy

ResearcherMicrobiology and ImmunologyUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses and email address may be missing. Find their university profile.

Jean-Pierre Routy

Researcher

Microbiology and Immunology

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
90 publications in the last five years, latest in 2026.
Senior (last) author on 17 recent papers, a sign of leading a research group.
Principal investigator on 3 research grants (3 CIHR), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

267

Publications

Citations

h-index

114

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Hiv Cure Hiv Latency Hiv Persistence Hiv Reservoirs Human Studies Humanized Mouse Models Memory Cd4+ T-Cells Myeloid Cells

Latest papers

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.
The Journal of allergy and clinical immunology · 2026
Increasing Handgrip Strength to Combat Frailty in Human Immunodeficiency Virus: Linking Immune Exhaustion to a Bone Health Indicator.
The Journal of infectious diseases · 2026 · first author
Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.
Research square · 2026

All 267 publications

Latest funding

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs
CIHR · 2025 · Co-investigator
$1,032,750
Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform
CIHR · 2025 · Co-investigator
$800,000
Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency
CIHR · 2024 · Co-investigator
$1,285,200

All 24 grants and awards

From the 150 most recent of 267 publications.

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Roussel L, Bernier S, Langelier M, Sun Y, Mak B, Li Y, Perez A, Wloski A, Angers I, Vinh LR, Beauchamp A, Boissel S, Watters AK, Rousseau S, Routy JP, Calderon V, Arias C, Vinh DC

The Journal of allergy and clinical immunology2026

DOI: 10.1016/j.jaci.2026.02.027 PMID: 41780571

Increasing Handgrip Strength to Combat Frailty in Human Immunodeficiency Virus: Linking Immune Exhaustion to a Bone Health Indicator.

Routy JP, Isnard S

The Journal of infectious diseases2026First author

DOI: 10.1093/infdis/jiag082 PMID: 41645731

Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.

Santangelo M, Bendoumou M, Dutilleul A, Khalfi S, Plant E, Ngassaki-Yoka CD, Pilosio L, Vanhulle C, Dias J, Marray T, Fattaccioli A, Verhasselt B, Lange U, Dieu M, Routy JP, Rohr O, Renard P, Ancuta P, VAN Lint C

Research square2026

DOI: 10.21203/rs.3.rs-9683098/v1 PMID: 42281995

Cell death-induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation.

Rong Y, Lambertucci F, Yang Y, Carbonnier V, Chen H, Dong Y, Mingoia S, Li S, Motiño O, Montégut L, Joseph A, Ferret L, Saavedra Díaz EG, Isnard S, Routy JP, Djavaheri-Mergny M, Castedo M, Fuerlinger A, Abdellatif M, Maiuri MC, Martins I, Kroemer G

Cell death and differentiation2026

DOI: 10.1038/s41418-026-01775-w PMID: 42236908

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4+ T-cells.

Moreira Gabriel E, Moreaux J, Kaofai C, Majidi Ivari K, Schmouth JF, Goulet JP, Dias J, Wiche Salinas TR, Raymond Marchand L, Khalfi S, Routy JP, Durand M, El-Far M, Tremblay CL, Ancuta P

Frontiers in immunology2026

DOI: 10.3389/fimmu.2026.1769388 PMID: 42273706

Comparative safety and efficacy of BIC/FTC/TAF versus DTG+3TC in antiretroviral treatment-naive patients with HIV as first-line regimens: A real-world cohort study.

Sun L, Jiang Y, Isnard S, Chen J, Li Y, Wang H, Zhao F, Rao M, Jia X, Huang J, Wu J, Luo Y, Zhao D, Liu C, Li X, Routy JP, Liu J, He Y, Cen P, Lu H

Bioscience trends2026

DOI: 10.5582/bst.2025.01335 PMID: 42036350

From suspected brain malignancy to Erdheim-Chester disease: the role of PET imaging and bone marrow biopsy in diagnosis.

Al-Abdulmalek A, Isnard S, Watters AA, Routy JP

Oxford medical case reports2026Senior author

DOI: 10.1093/omcr/omag049 PMID: 42117125

Identification of the cellular transcription factor KLF16 as a novel repressive epigenetic repressor of HIV-1 transcription.

Santangelo M, Bendoumou M, Dutilleul A, Khalfi S, Plant E, Ngassaki-Yoka CD, Pilosio L, Vanhulle C, Dias J, Marray T, Fattaccioli A, Dieu M, Routy JP, Rohr O, Renard P, Ancuta P, VAN Lint C

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.05.02.722432 PMID: 42146495

BRAF Alterations in Chronic Lymphocytic Leukemia: Genomic Landscape, Co-Mutation Patterns, and Clinical Relevance.

Al-Abdulmalek A, Landry E, Abdulgayoom M, Al-Mashdali AF, Dalol AA, Muthanna B, Routy JP, Mohamed SF

Current hematologic malignancy reports2026

DOI: 10.1007/s11899-026-00780-7 PMID: 42062666

Stroke From Paradoxical Embolism in a Young Patient With Sickle-Cell Disease and High Fetal Hemoglobin: A Diagnostic Challenge.

Luo YH, Zuberi N, Rizzolo A, Warner M, Isnard S, Routy JP

Clinical case reports2026Senior author

DOI: 10.1002/ccr3.72618 PMID: 42040366

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs

Co-investigatorCIHR2025Project Grant

Principal investigators: Chomont, Nicolas

Keywords: Bone Marrow; Gut; Hiv Reservoir; Innate Immune Sensing; Latency; Lymph Node; Mda5; Rig-I; Tissues

$1,032,750

Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform

Co-investigatorCIHR2025HIV/AIDS & STBBI Clinical Trials Research Network - Phase 2

Principal investigators: Durand, Madeleine; Beaudry, Sylvain; Fontaine, Guillaume; Gilbert, Caroline; Golchi, Shirin; Greenstreet, Peter J; Hedrich, Tanguy; Lebouché, Bertrand; Lessard, David; Vicente, Sergio

Keywords: Adaptive Trials; Hiv; Implementation Science; Stbbi; Training

$800,000

Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency

Co-investigatorCIHR2024Project Grant

Principal investigators: Ancuta, Petronela

Keywords: Antiretroviral Therapy; Aryl Hydrocarbon Receptor (Ahr); Confocal Microscopy/Imagestream; Crispr Cas9, Sirna; Flow Cytometry Analysis And Sorting; Hiv-1 Viral Reservoirs; Humanized Mice For Hiv Infection; Latency Reversing Agents; Pcr/Rt-Pcr, Western Blotting; Rna Sequencing, Massspec, Chip-Seq, Cut&Run, Atac-Seq

$1,285,200

Aging with HIV: understanding heterogeneity to promote health for all

Co-investigatorCIHR2024T. Gr.: Embracing Diversity -HIV/AIDS/STBBI-Co-infections and Co-morbidities-LOI

Principal investigators: Durand, Madeleine; Monteith, Kenneth M; Chartrand-Lefebvre, Carl; Murzin, Kate

Keywords: Aging; Comorbidity; Gender; Hiv; Inflammation; People Who Use Drugs

$19,690

The RESTART Trial: Reducing Systemic inflammation for people on AntiRetroviral Therapy.

Co-investigatorCIHR2024TG: Interv. Trial in Inflam. Chronic Cond. -CIHR HIV/AIDS/STBBI Res. Initiative

Principal investigators: Durand, Madeleine; Margolese, Shari L; Finzi, Andrés

Keywords: Aging; Cardiovascular; Comorbidity; Hiv; Inflammation

$1,999,997

Canadian HIV Cure Enterprise 3.0: Targeting tissue HIV reservoirs

Co-investigatorCIHR2024TG: Biomedical Res. for HIV/AIDS/STBBI-Next-Gen.Therapeutic Interv.-Large Team

Principal investigators: Chomont, Nicolas; Margolese, Shari L; Ancuta, Petronela; Angel, Jonathan B; Cohen, Eric A; Costiniuk, Cecilia T; Murooka, Thomas T

Keywords: Cd4 T Cells; Hiv Cure; Hiv Immunity; Hiv Persistence; Hiv Reservoir; Human Studies; Humanized Mouse Models; Myeloid Cells; Therapeutic Interventions; Tissue

$3,750,000

Metformin and Broadly Neutralizing Antibodies to Accelerate HIV-1 Reservoir Decay During ART

Co-investigatorCIHR2024Ca. Gr.: Biomedical Res. for HIV/AIDS/STBBI -Next-gen. therapeutic interventions

Principal investigators: Ancuta, Petronela

Keywords: Ampk, Mtor, Creb, Rorc2, Ahr, Pparg; Antibody-Dependent Cellular Cytotoxicity (Adcc) Assay; Antiretroviral Therapy; Broadly Neutralizing Antibodies (Bnabs); Cd4+ T Lymphocytes, Nk Cells; Hiv-1; Humanized Mice Nsg-Hil15; Metformin; Rna-Seq, Chip-Seq, Atac-Seq, Pcr, Rt-Pcr, Voa, Tilda; Viral Reservoirs

$200,000

Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency

Co-investigatorCIHR2023Project Grant - Priority Announcement: Infection and Immunity

Principal investigators: Ancuta, Petronela

Keywords: Antiretroviral Therapy; Confocal Microscopy/Imagestream; Crispr Cas9; Flow Cytometry Analysis And Sorting; Hiv-1; Humanized Mice For Hiv Infection; Latency Reversing Agents; Pcr/Rt-Pcr; Rna Sequencing; Viral Reservoirs

$100,000

Closing the Comorbidity Gap for People Living with HIV : a Randomized Controlled Trial of Fostemsavir to Reduce Inflammaging

Co-investigatorCIHR2023TG:Interv. Trial in Inflam. Chronic Cond. - CIHR HIV/AIDS & STBBI Res. Init. LOI

Principal investigators: Durand, Madeleine; Margolese, Shari L; Finzi, Andrés; Monteith, Kenneth M

Keywords: Aging; Cardiovascular; Comorbidity; Hiv; Inflammation

$20,000

Finding the Perfect Time to Hunt for HIV: A Tale of 36 Hours at the CHUM

Co-investigatorCIHR2023CIHR Café Scientifique Program - Institute of Infection and Immunity

Principal investigators: Ancuta, Petronela; Rosenes, Ron

Keywords: Antiretroviral Therapy; Circadian Clock; Community Consultants; Hiv Cure Strategies; Hiv Reservoirs; Immunological Measurements; Knowledge Users; People Living With Hiv; Residual Hiv Transcription; Virological Measurements

$6,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jean-Pierre Routy

Research

Latest papers

Latest funding

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Increasing Handgrip Strength to Combat Frailty in Human Immunodeficiency Virus: Linking Immune Exhaustion to a Bone Health Indicator.

Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.

Cell death-induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation.

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4+ T-cells.

Comparative safety and efficacy of BIC/FTC/TAF versus DTG+3TC in antiretroviral treatment-naive patients with HIV as first-line regimens: A real-world cohort study.

From suspected brain malignancy to Erdheim-Chester disease: the role of PET imaging and bone marrow biopsy in diagnosis.

Identification of the cellular transcription factor KLF16 as a novel repressive epigenetic repressor of HIV-1 transcription.

BRAF Alterations in Chronic Lymphocytic Leukemia: Genomic Landscape, Co-Mutation Patterns, and Clinical Relevance.

Stroke From Paradoxical Embolism in a Young Patient With Sickle-Cell Disease and High Fetal Hemoglobin: A Diagnostic Challenge.

Frequent collaborators

Jean-Pierre Routy

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Nicolas Chomont

Nicolas Chomont

Petronela Ancuta

Julie Bruneau

Ali Ahmad

Giada Sebastiani

Nadine Kronfli

Alexandra de Pokomandy

Cécile Tremblay

Julien Van Grevenynghe

Sharon Walmsley

Cecilia Costiniuk

Madeleine Durand

Cecilia Costiniuk

Marina Klein

Madeleine Durand

Kim Engler

Bertrand Routy

Shari Margolese

Mario Ostrowski

David Lessard

Michel Roger

Nicole Bernard

Sahar Saeed

Devendra Amre

Nicole Bernard

Mark Hull

Curtis Cooper

Christos Tsoukas

Christopher Power

Christos Tsoukas

Hugo Soudeyns

Nathalie Grandvaux

Guy Boivin

Rongtuan Lin

Nicolas Flamand