Faculty profile

Jean-Pierre Routy

ResearcherMedicineMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Jean-Pierre Routy

Researcher

Medicine

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
112 publications in the last five years, latest in 2026.
Senior (last) author on 21 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2024.
Supervised 1 trainee who won CIHR awards, most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

360

Publications

Citations

h-index

127

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Inflammation Hiv Gut Hiv Reservoirs Hiv/Aids Acyl Coa Binding Protein Autophagy Cd4 T-Cells

Latest papers

Plasma GDF-15 Levels Are Associated With HIV Reservoir Markers Independently of Inflammation in People With HIV on Antiretroviral Therapy.
The Journal of infectious diseases · 2026 · senior author
Safety and efficacy of switching to bictegravir-lenacapavir versus continuing bictegravir-emtricitabine-tenofovir alafenamide in virologically suppressed people with HIV-1 (ARTISTRY-2): a double-blind, multicentre, randomised, controlled, phase 3, non-inferiority trial.
The lancet. HIV · 2026
Material deprivation and its correlates in treatment-naïve migrants with HIV with rapid access to B/F/TAF at no cost: A sub-study of the ASAP cohort.
HIV medicine · 2026

All 360 publications

Latest funding

ACBP as a target for immunometabolic reprogramming in people living with HIV
CIHR · 2024 · Nominated PI
$738,224
CIHR Pan-Canadian Network for HIV/AIDS and Sexually Transmitted and Blood Borne Infections (STBBI) Clinical Trials Research (CTN)
CIHR · 2024 · Co-investigator
$25,000,000
Implementation of a patient portal and tailored patient-reported outcome measures to improve health problem detection and retention in HIV care: The DRHIVe Study
CIHR · 2022 · Co-investigator
$459,000

All 19 grants and awards

From the 150 most recent of 360 publications.

Plasma GDF-15 Levels Are Associated With HIV Reservoir Markers Independently of Inflammation in People With HIV on Antiretroviral Therapy.

Isnard S, Royston L, Berini CA, Mabanga T, Al-Abdulmalek A, Aiyana O, Sun L, El-Far M, Pagliuzza A, Planas D, Bu S, Pardesi MK, Fromentin R, Ancuta P, Durand M, Chomont N, Routy JP

The Journal of infectious diseases2026Senior author

DOI: 10.1093/infdis/jiag202 PMID: 41966981

Safety and efficacy of switching to bictegravir-lenacapavir versus continuing bictegravir-emtricitabine-tenofovir alafenamide in virologically suppressed people with HIV-1 (ARTISTRY-2): a double-blind, multicentre, randomised, controlled, phase 3, non-inferiority trial.

Meissner EG, Ramgopal M, Ruane PJ, Sanchez W, Crofoot G, Routy JP, Brinson C, DeJesus E, Martorell CT, Tellez M, Yokomaku Y, O'Reilly M, Lupo S, Schellberg S, Lezama-Mora JI, Chin B, Aizen K, D'Antoni ML, Huang H, Mponponsuo K, Montezuma-Rusca JM, Sklar P, Rhee M, Hung CC, ARTISTRY-2 Study Group

The lancet. HIV2026

DOI: 10.1016/s2352-3018(26)00078-0 PMID: 42105781

Material deprivation and its correlates in treatment-naïve migrants with HIV with rapid access to B/F/TAF at no cost: A sub-study of the ASAP cohort.

Laymouna M, Engler K, Lessard D, Belin M, Vicente S, Chu D, Yaphe S, Cox J, Kronfli N, Routy JP, Ishak J, Hamel A, Klein M, de Pokomandy A, Costiniuk CT, Lebouché B

HIV medicine2026

DOI: 10.1111/hiv.70299 PMID: 42592745

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Roussel L, Bernier S, Langelier M, Sun Y, Mak B, Li Y, Perez A, Wloski A, Angers I, Vinh LR, Beauchamp A, Boissel S, Watters AK, Rousseau S, Routy JP, Calderon V, Arias C, Vinh DC

The Journal of allergy and clinical immunology2026

DOI: 10.1016/j.jaci.2026.02.027 PMID: 41780571

Increasing Handgrip Strength to Combat Frailty in Human Immunodeficiency Virus: Linking Immune Exhaustion to a Bone Health Indicator.

Routy JP, Isnard S

The Journal of infectious diseases2026First author

DOI: 10.1093/infdis/jiag082 PMID: 41645731

Immunometabolic reprogramming via GLP-1 receptor agonists in people with HIV: A multidimensional systemic framework.

Sun L, Isnard S, Zhu H, Chen J, He Y, Lu H, Routy JP

Bioscience trends2026Senior author

DOI: 10.5582/bst.2026.01148 PMID: 42633920

Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.

Santangelo M, Bendoumou M, Dutilleul A, Khalfi S, Plant E, Ngassaki-Yoka CD, Pilosio L, Vanhulle C, Dias J, Marray T, Fattaccioli A, Verhasselt B, Lange U, Dieu M, Routy JP, Rohr O, Renard P, Ancuta P, VAN Lint C

Research square2026

DOI: 10.21203/rs.3.rs-9683098/v1 PMID: 42281995

Cell death-induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation.

Rong Y, Lambertucci F, Yang Y, Carbonnier V, Chen H, Dong Y, Mingoia S, Li S, Motiño O, Montégut L, Joseph A, Ferret L, Saavedra Díaz EG, Isnard S, Routy JP, Djavaheri-Mergny M, Castedo M, Fuerlinger A, Abdellatif M, Maiuri MC, Martins I, Kroemer G

Cell death and differentiation2026

DOI: 10.1038/s41418-026-01775-w PMID: 42236908

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4+ T-cells.

Moreira Gabriel E, Moreaux J, Kaofai C, Majidi Ivari K, Schmouth JF, Goulet JP, Dias J, Wiche Salinas TR, Raymond Marchand L, Khalfi S, Routy JP, Durand M, El-Far M, Tremblay CL, Ancuta P

Frontiers in immunology2026

DOI: 10.3389/fimmu.2026.1769388 PMID: 42273706

Comparative safety and efficacy of BIC/FTC/TAF versus DTG+3TC in antiretroviral treatment-naive patients with HIV as first-line regimens: A real-world cohort study.

Sun L, Jiang Y, Isnard S, Chen J, Li Y, Wang H, Zhao F, Rao M, Jia X, Huang J, Wu J, Luo Y, Zhao D, Liu C, Li X, Routy JP, Liu J, He Y, Cen P, Lu H

Bioscience trends2026

DOI: 10.5582/bst.2025.01335 PMID: 42036350

ACBP as a target for immunometabolic reprogramming in people living with HIV

Nominated PICIHR2024Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Acyl Coa Binding Protein; Autophagy; Cd4 T-Cells; Cd8 T-Cells; Hiv; Immune Response; Immunometabolic Reprogramming; Inflammation; Metabolism; Oxidative Phosphorylation

$738,224

CIHR Pan-Canadian Network for HIV/AIDS and Sexually Transmitted and Blood Borne Infections (STBBI) Clinical Trials Research (CTN)

Co-investigatorCIHR2024HIV/AIDS & STBBI Clinical Trials Research Network - Phase 1

Principal investigators: Klein, Marina B; Habanyama, Muluba; Mandarino, Enrico; Martin, Carrie; Angel, Jonathan B; Anis, Aslam H; Brophy, Jason C; Burchell, Ann N; Coffin, Carla S; Costiniuk, Cecilia T; Daley, Peter; Durand, Madeleine; Fontaine, Guillaume; Golchi, Shirin; Grennan, Jonathan (Troy); Hart, Trevor A; Hull, Mark W; Keynan, Yoav; King, Elizabeth M; Kronfli, Nadine; Law, John Lok Man; Lebouché, Bertrand; Logie, Carmen; Mbuagbaw, Lawrence C; McGuinty, Michaeline; Murray, Melanie C; Shaw, Souradet Y; Smyth, Daniel J; Spence, Cara J; Tan, Darrell H; Walmsley, Sharon L; Wong, Alexander C; Worthington, Catherine A; Zhabokritsky, Alice

Keywords: Clinical Trials; Community Engaged; Cure; Hepatitis B And C; Hiv/Aids; Network; Prevention; Sexually Transmitted And Blood Borne Infections; Syphilis; Treatment

$25,000,000

Implementation of a patient portal and tailored patient-reported outcome measures to improve health problem detection and retention in HIV care: The DRHIVe Study

Co-investigatorCIHR2022Project Grant

Principal investigators: Lebouché, Bertrand; Engler, Kim; Pomey, Marie-Pascale A; Schuster, Tibor

Keywords: Clinical Practice; Effectiveness; Hiv; Implementation; Patient Portal; Patient-Centered Care; Patient-Reported Outcome Measures; Retention In Care; Smartphone Application; Stakeholder Engagement

$459,000

Reversing CMV-induced gut damage to reduce inflammation and improve response to vaccine in people living with HIV

Nominated PICIHR2021Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Cytomegalovirus; Gut; Hiv; Inflammation; Letermovir; Vaccine

$589,052

Implementation of a patient portal and tailored patient-reported outcome measures to improve health problem detection and retention in HIV care: The DRHIVE Study

Co-investigatorCIHR2021Project Grant - Priority Announcement: HIV/AIDS and STBBI

Principal investigators: Lebouché, Bertrand; Engler, Kim; Pomey, Marie-Pascale A; Schuster, Tibor

Keywords: Clinical Practice; Hiv; Mobile Health; Patient Portal; Patient-Centered Care; Patient-Reported Outcome Measures; Retention In Care; Self-Management; Smartphone Application; Stakeholder Engagement

$100,000

Evaluation of a digital, rapid self-sampling strategy for individuals with suspected COVID-19 infection in South Africa and India

Principal investigatorCIHR2020Operating Grant: COVID-19 - Project Grant

Principal investigators: Pai, Nitika; Ahmad Khan, Faiz; Dheda, Keertan; Nair, Suma; Routy, Jean-Pierre

Keywords: Antigen Test; Applications; Covid-19; Diagnostics; Digital Strategy; Self-Sampling

$378,675

Immunosuppressive pathways and HIV reservoirs in tissues

Nominated PICIHR2019Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Checkpoint; Functional Cure; Gut; Hiv Reservoirs; Immune Exhaustion; Immunosuppression; Inflammation; Lymph Nodes; Myeloid Cells

$780,300

Locking out HIV from CD4 T cells: A pilot study of the impact of anti a4b7 antibody (vedolizumab) on viral control following analytical treatment interruption

Nominated PICIHR2017Operating Grant: Innovative Biomedical and Clinical HIV/AIDS Research

Principal investigators: Routy, Jean-Pierre

Keywords: Anti-A4b7 Antibody; Cd4 T Cells; Clinical Trial; Gut Damage; Hiv Cure; Hiv Reservoirs; Hiv/Aids; Innovative Methods; Novel Technologies; Viral Rebound

$247,650

Virus-cell interactions in the regulation of HIV translation

Co-investigatorCIHR2014Operating Grant

Principal investigators: Gatignol, Anne

Keywords: Adar1; Hiv; Hiv Infection; Hiv Translation; Innate Immunity; Lymphocytes; Monocytes; Pact; Pkr; Trbp

$481,439

Virus-cell interactions in the regulation of HIV translation

Co-investigatorCIHR2013Operating Grant - PA: HIV/AIDS Bridge Funding - Biomedical/Clinical Stream

Principal investigators: Gatignol, Anne

Keywords: Adar1; Hiv; Hiv Infection; Hiv Translation; Innate Immunity; Lymphocytes; Monocytes; Pact; Pkr; Trbp

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Jean-Pierre Routy

Research

Latest papers

Latest funding

Plasma GDF-15 Levels Are Associated With HIV Reservoir Markers Independently of Inflammation in People With HIV on Antiretroviral Therapy.

Safety and efficacy of switching to bictegravir-lenacapavir versus continuing bictegravir-emtricitabine-tenofovir alafenamide in virologically suppressed people with HIV-1 (ARTISTRY-2): a double-blind, multicentre, randomised, controlled, phase 3, non-inferiority trial.

Material deprivation and its correlates in treatment-na&#xef;ve migrants with HIV with rapid access to B/F/TAF at no cost: A sub-study of the ASAP cohort.

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Increasing Handgrip Strength to Combat Frailty in Human Immunodeficiency Virus: Linking Immune Exhaustion to a Bone Health Indicator.

Immunometabolic reprogramming via GLP-1 receptor agonists in people with HIV: A multidimensional systemic framework.

Identification of the cellular factor KLF16 as a novel epigenetic repressor of HIV-1 transcription.

Cell death-induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation.

Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4+ T-cells.

Comparative safety and efficacy of BIC/FTC/TAF versus DTG+3TC in antiretroviral treatment-naive patients with HIV as first-line regimens: A real-world cohort study.

Frequent collaborators

Jean-Pierre Routy

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Nicolas Chomont

Nicolas Chomont

Petronela Ancuta

Nadine Kronfli

Giada Sebastiani

Ali Ahmad

Alexandra de Pokomandy

Julie Bruneau

Marina Klein

Madeleine Durand

Cécile Tremblay

Madeleine Durand

Cecilia Costiniuk

Julien Van Grevenynghe

Kim Engler

Sharon Walmsley

Bertrand Routy

Cecilia Costiniuk

Shari Margolese

Mario Ostrowski

Nicole Bernard

Carl Chartrand-Lefebvre

Devendra Amre

Christopher Power

Christos Tsoukas

Curtis Cooper

Patrick Provost

Guy Boivin

George Thanassoulis

Igor Jurisica

Gilles Soulez

Wangari Tharao

Amrita Daftary

Michal Abrahamowicz

David Stephens

Rupert Kaul

Material deprivation and its correlates in treatment-naïve migrants with HIV with rapid access to B/F/TAF at no cost: A sub-study of the ASAP cohort.