Richard Bergeron, University of Ottawa

Research

Adhesive Removal Test Cylinder Test Endothelin-1 Horizontal Ladder Test Ischemia Necrosis Nfps Nmda Receptor

Latest papers

Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke.
iScience · 2022 · senior author
The sigma-1 receptor behaves as an atypical auxiliary subunit to modulate the functional characteristics of Kv1.2 channels expressed in HEK293 cells.
Physiological reports · 2019 · senior author
Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.
Haematologica · 2017

All 23 publications

Latest funding

Glycine Transporter Blockade and Neuroprotection
CIHR · 2017 · Nominated PI
$1,051,875
Amyloid beta sex specifically alters synaptic physiology
CIHR · 2017 · Nominated PI
$150,000
Modulation of Endoplasmic Reticulum Stress by Sigma Ligand
NSERC · 2015 · Principal investigator
$120,000

All 8 grants and awards

23 publications.

01

Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke.

Cappelli J, Khacho P, Wang B, Sokolovski A, Bakkar W, Raymond S, Ahlskog N, Pitney J, Wu J, Chudalayandi P, Wong AYC, Bergeron R

iScience2022Senior author

DOI: 10.1016/j.isci.2021.103539 PMID: 34977503

02

The sigma-1 receptor behaves as an atypical auxiliary subunit to modulate the functional characteristics of Kv1.2 channels expressed in HEK293 cells.

Abraham MJ, Fleming KL, Raymond S, Wong AYC, Bergeron R

Physiological reports2019Senior author

DOI: 10.14814/phy2.14147 PMID: 31222975

03

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.

Garcia-Santos D, Schranzhofer M, Bergeron R, Sheftel AD, Ponka P

Haematologica2017

DOI: 10.3324/haematol.2016.155671 PMID: 28495915

04

Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice.

Zhong H, Tong L, Gu N, Gao F, Lu Y, Xie RG, Liu J, Li X, Bergeron R, Pomeranz LE, Mackie K, Wang F, Luo CX, Ren Y, Wu SX, Xie Z, Xu L, Li J, Dong H, Xiong L, Zhang X

The Journal of clinical investigation2017

DOI: 10.1172/jci91038 PMID: 28463228

05

Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases.

Wong AY, Hristova E, Ahlskog N, Tasse LA, Ngsee JK, Chudalayandi P, Bergeron R

Molecular pharmacology2016Senior author

DOI: 10.1124/mol.116.104018 PMID: 27418673

06

Sigma receptor type 1 knockout mice show a mild deficit in plasticity but no significant change in synaptic transmission in the CA1 region of the hippocampus.

Snyder MA, McCann K, Lalande MJ, Thivierge JP, Bergeron R

Journal of neurochemistry2016Senior author

DOI: 10.1111/jnc.13695 PMID: 27260635

07

Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids.

Geddes SD, Assadzada S, Lemelin D, Sokolovski A, Bergeron R, Haj-Dahmane S, Béïque JC

Proceedings of the National Academy of Sciences of the United States of America2016

DOI: 10.1073/pnas.1522754113 PMID: 27114535

08

Differential effects of N-acetyl-aspartyl-glutamate on synaptic and extrasynaptic NMDA receptors are subunit- and pH-dependent in the CA1 region of the mouse hippocampus.

Khacho P, Wang B, Ahlskog N, Hristova E, Bergeron R

Neurobiology of disease2015Senior author

DOI: 10.1016/j.nbd.2015.08.017 PMID: 26303888

09

Time-dependent modulation of glutamate synapses onto 5-HT neurons by antidepressant treatment.

Geddes SD, Assadzada S, Sokolovski A, Bergeron R, Haj-Dahmane S, Béïque JC

Neuropharmacology2015

DOI: 10.1016/j.neuropharm.2015.02.027 PMID: 25747603

10

NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus.

Pabba M, Wong AY, Ahlskog N, Hristova E, Biscaro D, Nassrallah W, Ngsee JK, Snyder M, Beique JC, Bergeron R

The Journal of neuroscience : the official journal of the Society for Neuroscience2014Senior author

DOI: 10.1523/jneurosci.0458-14.2014 PMID: 25143613