Faculty profile

Amira Klip

ResearcherCell BiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Amira Klip

Researcher

Cell Biology

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
12 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (5 CIHR), most recently in 2014.
Supervised 4 trainees who won CIHR awards, most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

104

Publications

558

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Cell-Cell Communication Insulin Transcytosis Lipotoxicity Macrophage Activation Microvascular Endothelium Muscle Insulin Resistance Obesity-Induced Inflammation Glucose Transporters

Latest papers

KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arteriovenous malformations.
EMBO molecular medicine · 2026
A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise.
Physiological reviews · 2025 · senior author
Transcellular Barriers to Glucose Delivery in the Body.
Annual review of physiology · 2024 · first author

All 104 publications

Latest funding

The role of NOD1 in obesity-associated diabetes
CIHR · 2019 · Co-investigator
$940,950
Vulnerability of GLUT4 Translocation During Insulin Resistance: A Focus on Rab GTPases
CIHR · 2018 · Supervisor
$105,000
Cell biology and physiology of muscle insulin delivery, insulin action and insulin resistance leading to diabetes
CIHR · 2014 · Nominated PI
$2,311,753

All 10 grants and awards

104 publications.

KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arteriovenous malformations.

Wu R, Khosraviani N, Mansur A, Boudreau E, Largoza GE, Park S, Gustafson D, Raju S, Ching C, Klip A, Wälchli T, Howe KL, Radovanovic I, Wythe JD, Fish JE

EMBO molecular medicine2026

DOI: 10.1038/s44321-026-00383-y PMID: 41708990

A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise.

Richter EA, Bilan PJ, Klip A

Physiological reviews2025Senior author

DOI: 10.1152/physrev.00033.2024 PMID: 40173020

Transcellular Barriers to Glucose Delivery in the Body.

Klip A, De Bock K, Bilan PJ, Richter EA

Annual review of physiology2024First author

DOI: 10.1146/annurev-physiol-042022-031657 PMID: 38345907

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action.

Møller LLV, Ali MS, Davey J, Raun SH, Andersen NR, Long JZ, Qian H, Jeppesen JF, Henriquez-Olguin C, Frank E, Jensen TE, Højlund K, Wojtaszewski JFP, Nielsen J, Chiu TT, Jedrychowski MP, Gregorevic P, Klip A, Richter EA, Sylow L

Proceedings of the National Academy of Sciences of the United States of America2023

DOI: 10.1073/pnas.2211041120 PMID: 37364105

Palmitate-induced insulin resistance causes actin filament stiffness and GLUT4 mis-sorting without altered Akt signalling.

Tokarz VL, Mylvaganam S, Klip A

Journal of cell science2023Senior author

DOI: 10.1242/jcs.261300 PMID: 37815440

Measurement of GLUT4 Traffic to and from the Cell Surface in Muscle Cells.

Antonescu CN, Ishikura S, Bilan PJ, Klip A

Current protocols2023Senior author

DOI: 10.1002/cpz1.803 PMID: 37367531

Junctional integrity and directional mobility of lymphatic endothelial cell monolayers are disrupted by saturated fatty acids.

Tokarz VL, Pereira RVS, Jaldin-Fincati JR, Mylvaganam S, Klip A

Molecular biology of the cell2023Senior author

DOI: 10.1091/mbc.e22-08-0367 PMID: 36735487

Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation.

Tammineni ER, Figueroa L, Manno C, Varma D, Kraeva N, Ibarra CA, Klip A, Riazi S, Rios E

eLife2023

DOI: 10.7554/elife.78874 PMID: 36724092

Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner.

Wakefield CB, Lee VR, Johnston D, Boroumand P, Pillon NJ, Sayedyahossein S, O'Donnell BL, Tang J, Sanchez-Pupo RE, Barr KJ, Gros R, Flynn L, Borradaile NM, Klip A, Beier F, Penuela S

International journal of obesity (2005)2022

DOI: 10.1038/s41366-021-01037-4 PMID: 34897286

DCAF7 regulates cell proliferation through IRS1-FOXO1 signaling.

Frendo-Cumbo S, Li T, Ammendolia DA, Coyaud E, Laurent EMN, Liu Y, Bilan PJ, Polevoy G, Raught B, Brill JA, Klip A, Brumell JH

iScience2022

DOI: 10.1016/j.isci.2022.105188 PMID: 36248734

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Amira Klip

Research

Latest papers

Latest funding

KRAS-dependent glycolytic reprogramming of endothelial cells in sporadic arteriovenous malformations.

A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise.

Transcellular Barriers to Glucose Delivery in the Body.

The Rho guanine dissociation inhibitor &#x3b1; inhibits skeletal muscle Rac1 activity and insulin action.

Palmitate-induced insulin resistance causes actin filament stiffness and GLUT4 mis-sorting without altered Akt signalling.

Measurement of GLUT4 Traffic to and from the Cell Surface in Muscle Cells.

Junctional integrity and directional mobility of lymphatic endothelial cell monolayers are disrupted by saturated fatty acids.

Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation.

Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner.

DCAF7 regulates cell proliferation through IRS1-FOXO1 signaling.

Frequent collaborators

Jonathan Schertzer

Minna Woo

Adria Giacca

Brian Raught

Sheila Riazi

Silvia Penuela

Jun Liu

Bryan Heit

Michael Glogauer

Vuk Stambolic

Lauren Flynn

Warren Foltz

Robert Gros

Clinton Robbins

Ji Zhang

Ivan Radovanovic

Lily Zhou

Ahmed El-Sohemy

Kyoung-Han Kim

Chi-Chung Hui

Tak Mak

Gregory Steinberg

Constantine Samaan

Costin Antonescu

Frank Beier

Andras Nagy

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action.