This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Metabolomic atlas of ischemia-reperfusion injury in human lung transplants: Mitochondrial stress and primary graft dysfunction.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
Itaconate supplementation leads to improvement in donor lung function after extended hypothermic preservation.
The Journal of thoracic and cardiovascular surgery · 2026
Safety risks of intratracheal lipid nanoparticle gene delivery to the lung and potential mitigation strategies.
The Journal of thoracic and cardiovascular surgery · 2026
Latest funding
- $1,067,175
Harnessing Lung's Ability to Hibernate: Strategies to Achieve Multiday Organ Preservation
CIHR · 2025 · Principal investigator
- $1,101,600
Genetic Engineering of Lungs to Create Universal Blood Type Donor Organs
CIHR · 2024 · Principal investigator
- $933,299
Lung transplant to evaluate advanced novel organ modification therapies using a human decedent model
CIHR · 2024 · Co-investigator
27 publications.
Metabolomic atlas of ischemia-reperfusion injury in human lung transplants: Mitochondrial stress and primary graft dysfunction.
Liang L, Zhao Y, Wang A, Zhu B, Hsin MK, Cypel M, Keshavjee S, Liu M
Itaconate supplementation leads to improvement in donor lung function after extended hypothermic preservation.
Siebiger G, Wang A, Yune J, Montagne J, Garza G, Lima T, Yamanashi K, Oliveira P, Gao FY, Zhang Y, Bellissimo CA, Aujla T, Beroncal E, Ali A, Goligher EC, Andreazza AC, Liu M, Keshavjee S, Cypel M
Safety risks of intratracheal lipid nanoparticle gene delivery to the lung and potential mitigation strategies.
Nagoya A, Nakajima K, Yune J, Wang A, Guan Z, Xu Y, Dong S, Strilchuk A, Li B, Juvet S, Cypel M, Liu M, Keshavjee S
Angiotensin-(1-7) preconditioning during 10°C static preservation improves early post-transplant graft function in a rat lung transplantation model.
Oliveira P, Wang A, Yamanashi K, Zhang Y, Pal P, Garza G, Montagne J, Siebiger G, Furie N, Yune J, Keshavjee S, Pêgo-Fernandes PM, Cypel M
Metabolic changes during cold ischemic preservation and reperfusion in porcine lung transplants.
Liang L, Hsin MK, Zhao Y, Wang A, Machuca T, Yeung J, Cypel M, Keshavjee S, Liu M
Protective effects of 10 °C preservation on donor lungs with lipopolysaccharide-induced acute lung injury.
Yamanashi K, Wang A, Bellissimo CA, Siebiger G, Oliveira P, Zhang Y, Montagne J, Garza G, Furie N, Pal P, Liu M, Goligher EC, Keshavjee S, Cypel M
The combination of postmortem sevoflurane ventilation and in situ topical cooling provides improved 6 hours lung preservation in an uncontrolled DCD porcine model.
Junior ERB, Wang A, Ribeiro RVP, Beroncal EL, Ramadan K, Michaelsen VS, Chen M, Ali A, Zhang Y, Pal P, Abdelnour E, Siebiger G, Pinto BM, Waddell T, Andreazza AC, Keshavjee S, Cypel M
Feasibility and Safety of Ex Vivo Delivery of Rituximab to Lung Allografts in Transplant Recipients at High Risk for Epstein-Barr Virus-associated Posttransplant Lymphoproliferative Disorder.
Ferreira VH, Ribeiro RVP, Mavandadnejad F, Ierullo M, Majchrzak-Kita B, Wang A, Singer L, Keshavjee S, Cypel M, Kumar D, Humar A
Metabolomic studies reveal an organ-protective hibernation state in donor lungs preserved at 10 °C.
Wang A, Ali A, Baciu C, Bellissimo C, Siebiger G, Yamanashi K, Montagne J, Garza G, Goligher E, Keshavjee S, Liu M, Cypel M
Angiotensin-converting enzyme 2 activation attenuates inflammation and oxidative stress in brain death donor followed by rat lung transplantation.
Oliveira-Melo P, Nepomuceno NA, Ruiz LM, Correia AT, Vilela VS, de Oliveira Braga KA, Manzuti GM, Feitosa DDM, Kennedy-Feitosa E, Wang A, Cypel M, Fernandes PMP
Harnessing Lung's Ability to Hibernate: Strategies to Achieve Multiday Organ Preservation
Principal investigators: Cypel, Marcelo; Kluger, Ronald H; Wang, Aizhou
Keywords: Energy Supply; Extended Organ Preservation Time; Lung Transplantation; Mitochondrial Function; Normothermic Ex Vivo Lung Perfusion; Organ Preservation
Genetic Engineering of Lungs to Create Universal Blood Type Donor Organs
Principal investigators: Cypel, Marcelo; Wang, Aizhou
Keywords: Abo Incompatible Transplant; Crispr; Ex Vivo Lung Perfusion; Genome Editing; Lung Transplantation; Organ Engineering
Lung transplant to evaluate advanced novel organ modification therapies using a human decedent model
Principal investigators: Cypel, Marcelo; Gross, Jed A; Humar, Atul
Keywords: Bioethics; Donation; Ex Vivo Lung Perfusion; Human Decedent Model; Lung Transplantation; Organ Modification
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Thoracic Surgery
- Department of Surgery
- Infectious Diseases
- Department of Medicine
- Toronto General Research Institute
- Critical Care Medicine
- Pharmaceutical Sciences
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Marcelo Cypel
Thoracic Surgery
24 shared papers, latest 2026
Shaf Keshavjee
Thoracic Surgery
20 shared papers, latest 2026
Mingyao Liu
Department of Surgery
13 shared papers, latest 2026
Jonathan Yeung
Department of Surgery
5 shared papers, latest 2025
Atul Humar
Infectious Diseases
3 shared papers, latest 2025
Deepali Kumar
Infectious Diseases
3 shared papers, latest 2025
Ronald Kluger
Thoracic Surgery
3 shared papers, latest 2019
Stephen Juvet
Toronto General Research Institute
2 shared papers, latest 2026
Laurent Brochard
Critical Care Medicine
2 shared papers, latest 2022
Eddy Fan
Department of Medicine
2 shared papers, latest 2022
Janusz Pawliszyn
Faculty
2 shared papers, latest 2024
Christine Cserti-Gazdewich
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2022
Tereza Martinu
Toronto General Research Institute
1 shared papers, latest 2023
Jim Hu
Faculty
1 shared papers, latest 2024
Lianne Singer
Physical Therapy
1 shared papers, latest 2025
Lori West
Pediatrics
1 shared papers, latest 2022
Kazuhiro Yasufuku
Department of Surgery
1 shared papers, latest 2022
Ewan Goligher
Department of Medicine
1 shared papers, latest 2025
Lorenzo Del Sorbo
Faculty
1 shared papers, latest 2021
Bowen Li
Pharmaceutical Sciences
1 shared papers, latest 2026
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