Faculty profile
Aleksander Hinek
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Read how they describe their research on their University of Toronto profile.
Latest papers
Efficacy of Sodium Tanshinone IIA Sulfonate in Patients with Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Results from a Multicentre, Controlled, Randomized Trial.
Cardiovascular drugs and therapy · 2021 · senior author
Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA.
British journal of cancer · 2019
Experimental Right Ventricular Hypertension Induces Regional β1-Integrin-Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling.
Journal of the American Heart Association · 2018
Latest funding
- $625,471
Serine carboxypeptidases that inactivate short vasoactive peptides: roles in vasoconstriction and proliferation of vascular SMCs
CIHR · 2009 · Co-investigator
Kawasaki disease-From the bench to the bedside and back
CIHR · 2008 · Co-investigator
- $100,000
Carboxypeptidases that inactivate short vasoactive peptides: roles in vasoconstriction and proliferation of vascular SMCs
CIHR · 2008 · Co-investigator
27 publications.
Efficacy of Sodium Tanshinone IIA Sulfonate in Patients with Non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Results from a Multicentre, Controlled, Randomized Trial.
Mao S, Wang L, Zhao X, Guo L, Lin Q, Wang X, Dai X, Shang H, Zhang M, Hinek A
Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA.
Brassart B, Da Silva J, Donet M, Seurat E, Hague F, Terryn C, Velard F, Michel J, Ouadid-Ahidouch H, Monboisse JC, Hinek A, Maquart FX, Ramont L, Brassart-Pasco S
Experimental Right Ventricular Hypertension Induces Regional β1-Integrin-Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling.
Sun M, Ishii R, Okumura K, Krauszman A, Breitling S, Gomez O, Hinek A, Boo S, Hinz B, Connelly KA, Kuebler WM, Friedberg MK
Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings
Xuefang Pan, Yanting Wang, Torben Lübke, Aleksander Hinek, Alexey V. Pshezhetsky
The antidiabetic hormone glucagon-like peptide-1 induces formation of new elastic fibers in human cardiac fibroblasts after cross-activation of IGF-IR.
Qa'aty N, Wang Y, Wang A, Mao S, Vincent M, Husain M, Hinek A
Synthetic ligands of the elastin receptor induce elastogenesis in human dermal fibroblasts via activation of their IGF-1 receptors.
Qa'aty N, Vincent M, Wang Y, Wang A, Mitts TF, Hinek A
Type V OI primary osteoblasts display increased mineralization despite decreased COL1A1 expression.
Reich A, Bae AS, Barnes AM, Cabral WA, Hinek A, Stimec J, Hill SC, Chitayat D, Marini JC
Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1.
Pan X, Grigoryeva L, Seyrantepe V, Peng J, Kollmann K, Tremblay J, Lavoie JL, Hinek A, Lübke T, Pshezhetsky AV
Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts.
Mao S, Wang Y, Zhang M, Hinek A
Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin.
Hinek A, Kim HJ, Wang Y, Wang A, Mitts TF
Serine carboxypeptidases that inactivate short vasoactive peptides: roles in vasoconstriction and proliferation of vascular SMCs
Principal investigators: Pshezhetsky, Alexey V
Keywords: Angiotensin; Carboxypeptidases; Cathepsin A; Endothelin; Remodelling; Smooth Muscle Cells; Transgenic Mice; Vascular Peptides
Kawasaki disease-From the bench to the bedside and back
Principal investigators: Yeung, Rae S
Keywords: Animal Models; Costimulation; Elastin Signaling; Genetic Variants; Kawasaki Disease; T-Cell Activation
Carboxypeptidases that inactivate short vasoactive peptides: roles in vasoconstriction and proliferation of vascular SMCs
Principal investigators: Pshezhetsky, Alexey V
Keywords: Angiotensin; Carboxypeptidases; Cathepsin A; Endothelin; Remodelling; Smooth Muscle Cells; Transgenic Mice; Vascular Peptides
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke, Brain Canada and the New Frontiers in Research Fund.
Frequent collaborators
- Seema Mital and James Ellis: 21 shared papers
- Kim Connelly and Mark Friedberg: 17 shared papers
- Rosanna Weksberg and David Chitayat: 16 shared papers
- John Coles and Osami Honjo: 14 shared papers
- Wolfgang Kuebler and Kim Connelly: 12 shared papers
- Mark Friedberg and Osami Honjo: 11 shared papers
- Rosanna Weksberg and Roberto Mendoza-Londono: 9 shared papers
- David Chitayat and Roberto Mendoza-Londono: 9 shared papers
- James Ellis and William Stanford: 7 shared papers
- Andrew Howard and Roberto Mendoza-Londono: 7 shared papers
- Wolfgang Kuebler and Mark Friedberg: 6 shared papers
- Cynthia Hawkins and Rosanna Weksberg: 6 shared papers
- Mansoor Husain and Kim Connelly: 6 shared papers
- Mansoor Husain and Peter Liu: 6 shared papers
- Seema Mital and Mark Friedberg: 6 shared papers
- David Chitayat and Aleksander Hinek: 6 shared papers
- John Coles and Mark Friedberg: 6 shared papers
- Cynthia Hawkins and William Stanford: 5 shared papers
- Seema Mital and Peter Liu: 5 shared papers
- William Stanford and Peter Liu: 4 shared papers
- Aleksander Hinek and Andrew Wang: 4 shared papers
- Cynthia Hawkins and David Chitayat: 3 shared papers
- David Chitayat and Walter Kahr: 3 shared papers
- David Chitayat and Elaine Goh: 3 shared papers
- John Coles and Peter Liu: 3 shared papers
- Elaine Goh and Roberto Mendoza-Londono: 3 shared papers
- Wolfgang Kuebler and Osami Honjo: 2 shared papers
- Cynthia Hawkins and Aleksander Hinek: 2 shared papers
- Mansoor Husain and John Coles: 2 shared papers
- Mansoor Husain and Aleksander Hinek: 2 shared papers
- James Ellis and Rosanna Weksberg: 2 shared papers
- David Chitayat and Vibhuti Shah: 2 shared papers
- William Stanford and Paul Fedak: 2 shared papers
- Kim Connelly and Paul Fedak: 2 shared papers
- Walter Kahr and Roberto Mendoza-Londono: 2 shared papers
- Claudia Lace de Almeida and Aleksander Hinek: 1 shared paper
- Claudia Lace de Almeida and Osami Honjo: 1 shared paper
- Wolfgang Kuebler and Boris Hinz: 1 shared paper
- Wolfgang Kuebler and Aleksander Hinek: 1 shared paper
- Cynthia Hawkins and Vibhuti Shah: 1 shared paper
- Cynthia Hawkins and Walter Kahr: 1 shared paper
- Mansoor Husain and Boris Hinz: 1 shared paper
- Mansoor Husain and Paul Fedak: 1 shared paper
- Mansoor Husain and Andrew Wang: 1 shared paper
- Seema Mital and Aleksander Hinek: 1 shared paper
- James Ellis and Aleksander Hinek: 1 shared paper
- Boris Hinz and Kim Connelly: 1 shared paper
- Boris Hinz and Aleksander Hinek: 1 shared paper
- Rosanna Weksberg and Vibhuti Shah: 1 shared paper
- Rosanna Weksberg and Aleksander Hinek: 1 shared paper
- David Chitayat and Andrew Howard: 1 shared paper
- David Chitayat and Jennifer Stimec: 1 shared paper
- William Stanford and Aleksander Hinek: 1 shared paper
- Julie Lavoie and Aleksander Hinek: 1 shared paper
- Kim Connelly and Aleksander Hinek: 1 shared paper
- Vibhuti Shah and Aleksander Hinek: 1 shared paper
- Paul Fedak and Aleksander Hinek: 1 shared paper
- Walter Kahr and Andrew Howard: 1 shared paper
- Walter Kahr and Elaine Goh: 1 shared paper
- Walter Kahr and Aleksander Hinek: 1 shared paper
- John Coles and Aleksander Hinek: 1 shared paper
- Mark Friedberg and Aleksander Hinek: 1 shared paper
- Andrew Howard and Aleksander Hinek: 1 shared paper
- Andrew Howard and Jennifer Stimec: 1 shared paper
- Elaine Goh and Aleksander Hinek: 1 shared paper
- Peter Liu and Aleksander Hinek: 1 shared paper
- Aleksander Hinek and Osami Honjo: 1 shared paper
- Aleksander Hinek and Jennifer Stimec: 1 shared paper
- Aleksander Hinek and Roberto Mendoza-Londono: 1 shared paper
- Andrew Wang and Roberto Mendoza-Londono: 1 shared paper
- Department of Laboratory Medicine & Pathobiology
- Department of Surgery
- Institute of Medical Science
- Department of Paediatrics
- Department of Psychiatry
- Matrix Dynamics Group
- Department of Pediatrics
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
David Chitayat
Department of Paediatrics
6 shared papers, latest 2015
Andrew Wang
Department of Psychiatry
4 shared papers, latest 2015
Alexey Pshezhetsky
Faculty
4 shared papers, latest 2017
Cynthia Hawkins
Department of Laboratory Medicine & Pathobiology
2 shared papers, latest 2012
Mansoor Husain
Department of Laboratory Medicine & Pathobiology
2 shared papers, latest 2015
Osami Honjo
Department of Surgery
1 shared papers, latest 2009
Jennifer Stimec
Department of Medical Imaging
1 shared papers, latest 2015
Roberto Mendoza-Londono
Department of Paediatrics
1 shared papers, latest 2012
Boris Hinz
Matrix Dynamics Group
1 shared papers, latest 2018
Rosanna Weksberg
Institute of Medical Science
1 shared papers, latest 2012
William Stanford
Department of Cellular and Molecular Medicine
1 shared papers, latest 2013
Julie Lavoie
Department of Biochemistry and Molecular Medicine
1 shared papers, latest 2014
Johanne Tremblay
Department of Medicine
1 shared papers, latest 2014
Kim Connelly
Department of Medicine
1 shared papers, latest 2018
Gideon Koren
Faculty
1 shared papers, latest 2009
Vibhuti Shah
Institute of Health Policy, Management, and Evaluation
1 shared papers, latest 2012
Paul Fedak
Department of Physiology & Pharmacology
1 shared papers, latest 2006
Walter Kahr
Department of Biochemistry
1 shared papers, latest 2012
John Coles
Department of Surgery
1 shared papers, latest 2006
Mark Friedberg
Institute of Medical Science
1 shared papers, latest 2018
Andrew Howard
Department of Surgery
1 shared papers, latest 2012
Elaine Goh
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2012
Claudia Lace de Almeida
Department of Pediatrics
1 shared papers, latest 2009
Peter Liu
SCE
1 shared papers, latest 2009
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.