This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Latest papers
Sex dependent genetic architecture of biochemically verified tobacco use.
Psychiatry research · 2025
Genetic Prediction of Smoking Cessation Medication Side Effects: A Genome-Wide Investigation of Abnormal Dreams on Varenicline.
Clinical pharmacology and therapeutics · 2024
CYP2A6 associates with respiratory disease risk and younger age of diagnosis: a phenome-wide association Mendelian Randomization study.
Human molecular genetics · 2024
Latest funding
- $929,475
Precision medicine in smoking cessation: nicotine metabolism genetics in nine clinical trials
CIHR · 2018 · Nominated PI
- $199,619
Do men and women differ in how pharmacogenetics optimizes smoking cessation therapy?
CIHR · 2017 · Co-investigator
- $2,223,982
Variation in Drug Metabolism and Response
CIHR · 2016 · Co-investigator
36 publications.
Sex dependent genetic architecture of biochemically verified tobacco use.
Chenoweth MJ, Lerman C, Knight J, Tyndale RF
Genetic Prediction of Smoking Cessation Medication Side Effects: A Genome-Wide Investigation of Abnormal Dreams on Varenicline.
Chenoweth MJ, Kim YJ, Nollen NL, Hawk LW, Mahoney MC, Lerman C, Knight J, Tyndale RF
CYP2A6 associates with respiratory disease risk and younger age of diagnosis: a phenome-wide association Mendelian Randomization study.
Giratallah H, Chenoweth MJ, Pouget JG, El-Boraie A, Alsaafin A, Lerman C, Knight J, Tyndale RF
Influence of CYP2A6 Genetic Variation, Nicotine Dependence Severity, and Treatment on Smoking Cessation Success.
Chenoweth MJ, Lerman C, Knight J, Tyndale RF
Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes.
Langlois AWR, El-Boraie A, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Knight J, Scherer SE, Chenoweth MJ, Tyndale RF
Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis.
Chenoweth MJ, Peng AR, Zhu AZX, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Knight J, Swardfager W, Tyndale RF
Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans.
Chenoweth MJ, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Lerman C, Knight J, Tyndale RF
A Genome-Wide Association Study of Nausea Incidence in Varenicline-Treated Cigarette Smokers.
Chenoweth MJ, Lerman C, Knight J, Tyndale RF
Late-onset epilepsy predicts stroke: Systematic review and meta-analysis.
Wall J, Knight J, Emsley HCA
Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study.
Winterburn JL, Voineskos AN, Devenyi GA, Plitman E, de la Fuente-Sandoval C, Bhagwat N, Graff-Guerrero A, Knight J, Chakravarty MM
Precision medicine in smoking cessation: nicotine metabolism genetics in nine clinical trials
Principal investigators: Knight, Jo
Keywords: Biomarkers; Nicotine Metabolism; Precision Medicine; Smoking Cessation; Tobacco
Do men and women differ in how pharmacogenetics optimizes smoking cessation therapy?
Principal investigators: Tyndale, Rachel F
Keywords: Gender Differences; Medication Adherence; Personalized Medicine; Pharmacogenetics; Pharmacokinetic Variation; Sex Differences; Smoking Cessation
Variation in Drug Metabolism and Response
Principal investigators: Tyndale, Rachel F
Keywords: Drug Dependence; Drug Metabolism; Neuropharmacology; Neurotoxicity; Opioids; Pharmacogenomics; Smoking
Variation in nicotine metabolism in nine clinical trials: a genomics approach to personalizing smoking cessation
Principal investigators: Tyndale, Rachel F
Keywords: Biomarkers; Nicotine Metabolism; Precision Medicine; Smoking Cessation; Tobacco
Cohort to illuminate Neurodegeneration, Genetics, Imaging Associations and Leukoaraiosis (CONGENIAL)
Principal investigators: Black, Sandra E; Masellis, Mario
Keywords: And Lewy Body); Apathy); Dementia (Alzheimer'S; Depression; Frontotemporal; Imaging-Genetics; Longitudinal Cohort; Mri (Structural/Functional); Neurobehaviour (E.G.; Neuropathology; Neuropsychology; Spect; Vascular Cognitive Disorders
Phenotype and Genotype Data Reduction for Machine Learning Classifier in Alzheimer's Disease
Principal investigators: Patel, Sejal
Keywords: Alzheimer'S Disease; Bioinformatics; Gene Ontology; Genetics; Heritability Analysis; Machine Learning; Statistical Genetics; Structural Magnetic Resonance Imaging
Data Integration in Human Genetic Research
Principal investigators: Knight, Joanne
Imaging-genetics biomarkers for disease risk in Alzheimer's Disease.
Principal investigators: Chakravarty, Mallar; Pruessner, Jens C
Keywords: Alzheimer'S Disease; Computational Neuroanatomy; Mild Cognitive Impairment; Mri; Temporal Lobes
Genetic Frontotemporal Dementia Initiative (GENFI) in Canada
Principal investigators: Masellis, Mario; Finger, Elizabeth
Keywords: Biomarkers; C9orf72; Cognition; Frontotemporal Dementia; Genomics; Mapt; Mri; Prgn
Genetics of Reading Disabilities
Principal investigators: Barr, Cathy L
Keywords: Dyslexia; Gene Expression; Gene Function; Genetics; Reading Disabilities
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Biostatistics Division
- Research Imaging Center
- Psychiatry
- Department of Psychiatry
- Department of Pharmacology and Toxicology
- Department of Laboratory Medicine and Pathobiology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Mario Masellis
Medicine
5 shared papers, latest 2019
Wei Xu
Biostatistics Division
3 shared papers, latest 2016
Daniel Felsky
Department of Psychiatry
2 shared papers, latest 2017
John Strauss
Faculty
2 shared papers, latest 2015
Walter Swardfager
Department of Pharmacology and Toxicology
2 shared papers, latest 2022
Ekaterina Rogaeva
Tanz Centre for Research in Neurodegenerative Diseases
1 shared papers, latest 2019
Arun Tiwari
Faculty
1 shared papers, latest 2016
Abdul Noor
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2014
Pingzhao Hu
Biostatistics Division
1 shared papers, latest 2014
Anne Griffiths
Pediatric Gastroenterology and Nutrition
1 shared papers, latest 2016
Ariel Graff-Guerrero
Research Imaging Center
1 shared papers, latest 2019
Kenneth Croitoru
Immunology
1 shared papers, latest 2015
Constantin Polychronakos
Pediatrics
1 shared papers, latest 2016
Peter ST GEORGE-HYSLOP
Medicine
1 shared papers, latest 2019
Vinod Chandran
Rheumatology
1 shared papers, latest 2015
Gary Remington
Research Imaging Center
1 shared papers, latest 2016
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