Faculty profile

Chiara Gorrini

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Chiara Gorrini

Researcher

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Principal investigator on 1 research grant (1 CIHR), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Targeting Aryl Hydrocarbon Receptor

Latest papers

Unveiling the developmental and tumor-suppressive roles of the p53 variant p53psi.
Proceedings of the National Academy of Sciences of the United States of America · 2026 · first author
Corrigendum: Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.
Frontiers in oncology · 2024
Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.
Frontiers in oncology · 2024

All 23 publications

Latest funding

Targeting aryl hydrocarbon receptor as novel vulnerability in triple negative breast cancers
CIHR · 2018 · Nominated PI
$65,000

All 1 grants and awards

23 publications.

Unveiling the developmental and tumor-suppressive roles of the p53 variant p53psi.

Gorrini C, Jafari S, Duncan G, Snow B, Hendrikse L, McLoughlin L, Haight J, Wakeham A, Tobin C, Elia A, Ramachandran P, Law R, Gang B, Lu TL, Morgado-Palacin I, You-Ten A, Berger T, Sordella R, Mak TW

Proceedings of the National Academy of Sciences of the United States of America2026First author

DOI: 10.1073/pnas.2427242123 PMID: 41871246

Corrigendum: Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.

Olafsen NE, Das S, Gorrini C, Matthews J

Frontiers in oncology2024

DOI: 10.3389/fonc.2024.1516633 PMID: 39628995

Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.

Olafsen NE, Das S, Gorrini C, Matthews J

Frontiers in oncology2024

DOI: 10.3389/fonc.2024.1466658 PMID: 39450255

Caspase-1-dependent spatiality in triple-negative breast cancer and response to immunotherapy.

Zheng W, Marini W, Murakami K, Sotov V, Butler M, Gorrini C, Ohashi PS, Reedijk M

Nature communications2024

DOI: 10.1038/s41467-024-52553-6 PMID: 39353903

Breast cancer immune microenvironment: from pre-clinical models to clinical therapies.

Wilson BE, Gorrini C, Cescon DW

Breast cancer research and treatment2022

DOI: 10.1007/s10549-021-06431-0 PMID: 34731350

The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer.

Bassi C, Fortin J, Snow BE, Wakeham A, Ho J, Haight J, You-Ten A, Cianci E, Buckler L, Gorrini C, Stambolic V, Mak TW

Cell death and differentiation2021

DOI: 10.1038/s41418-021-00799-8 PMID: 34059798

Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.

Herranz C, Mateo F, Baiges A, Ruiz de Garibay G, Junza A, Johnson SR, Miller S, García N, Capellades J, Gómez A, Vidal A, Palomero L, Espín R, Extremera AI, Blommaert E, Revilla-López E, Saez B, Gómez-Ollés S, Ancochea J, Valenzuela C, Alonso T, Ussetti P, Laporta R, Xaubet A, Rodríguez-Portal JA, Montes-Worboys A, Machahua C, Bordas J, Menendez JA, Cruzado JM, Guiteras R, Bontoux C, La Motta C, Noguera-Castells A, Mancino M, Lastra E, Rigo-Bonnin R, Perales JC, Viñals F, Lahiguera A, Zhang X, Cuadras D, van Moorsel CHM, van der Vis JJ, Quanjel MJR, Filippakis H, Hakem R, Gorrini C, Ferrer M, Ugun-Klusek A, Billett E, Radzikowska E, Casanova Á, Molina-Molina M, Roman A, Yanes O, Pujana MA

EMBO molecular medicine2021

DOI: 10.15252/emmm.202113929 PMID: 34378323

Immune Cell Associations with Cancer Risk.

Palomero L, Galván-Femenía I, de Cid R, Espín R, Barnes DR, Cimba, Blommaert E, Gil-Gil M, Falo C, Stradella A, Ouchi D, Roso-Llorach A, Violan C, Peña-Chilet M, Dopazo J, Extremera AI, García-Valero M, Herranz C, Mateo F, Mereu E, Beesley J, Chenevix-Trench G, Roux C, Mak T, Brunet J, Hakem R, Gorrini C, Antoniou AC, Lázaro C, Pujana MA

iScience2020

DOI: 10.1016/j.isci.2020.101296 PMID: 32622267

Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.

Roux C, Jafari SM, Shinde R, Duncan G, Cescon DW, Silvester J, Chu MF, Hodgson K, Berger T, Wakeham A, Palomero L, Garcia-Valero M, Pujana MA, Mak TW, McGaha TL, Cappello P, Gorrini C

Proceedings of the National Academy of Sciences of the United States of America2019Senior author

DOI: 10.1073/pnas.1819473116 PMID: 30770442

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.

Kubli SP, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, Jafari SM, Snow B, Jones L, Palomero L, Thu KL, Cassetta L, Soong D, Berger T, Ramachandran P, Baniasadi SP, Duncan G, Lindzen M, Yarden Y, Herranz C, Lazaro C, Chu MF, Haight J, Tinto P, Silvester J, Cescon DW, Petit A, Pettersson S, Pollard JW, Mak TW, Pujana MA, Cappello P, Gorrini C

Proceedings of the National Academy of Sciences of the United States of America2019Senior author

DOI: 10.1073/pnas.1815126116 PMID: 30733286

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Chiara Gorrini

Research

Latest papers

Latest funding

Unveiling the developmental and tumor-suppressive roles of the p53 variant p53psi.

Corrigendum: Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.

Long-term exposure to BAY2416964 reduces proliferation, migration and recapitulates transcriptional changes induced by AHR loss in PyMT-induced mammary tumor cells.

Caspase-1-dependent spatiality in triple-negative breast cancer and response to immunotherapy.

Breast cancer immune microenvironment: from pre-clinical models to clinical therapies.

The PTEN and ATM axis controls the G1/S cell cycle checkpoint and tumorigenesis in HER2-positive breast cancer.

Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.

Immune Cell Associations with Cancer Risk.

Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.

Targeting aryl hydrocarbon receptor as novel vulnerability in triple negative breast cancers

Frequent collaborators

Rama Khokha

Mathieu Lupien

Vuk Stambolic

Jason Matthews

David Cescon

Marcus Butler

Yi Sheng

Michael Reedijk

Andrea Jurisicova

Jacques Simard

Tak Mak