This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
The role of stereotactic body radiotherapy in oligoprogressive breast cancer: A site-specific analysis of the prospective, phase-II RADIANT trial.
Clinical and translational radiation oncology · 2026
FAM72A promotes UNG2 degradation and mutagenesis in human cancer cells.
Scientific reports · 2025
Detection of metabolic adaptation in a triple-negative breast cancer animal model with [18F]choline-PET imaging as a surrogate for drug resistance.
European journal of nuclear medicine and molecular imaging · 2024
Latest funding
- $872,100
Rebooting Sensitivity to Checkpoint Blockade Therapy in TNBC (RESETT)
CIHR · 2026 · Co-investigator
- $1,147,500
Finding vulnerabilities in advanced breast cancer from the chromatin state of repeat DNA
CIHR · 2025 · Co-investigator
- $852,975
198Au-Nanodepot Combined with Adjuvant Auger Electron Radioimmunotherapy, Immunotherapy and Chemotherapy for Triple-Negative Breast Cancer in Metastatic Humanized Mouse Models
CIHR · 2024 · Co-investigator
14 publications.
The role of stereotactic body radiotherapy in oligoprogressive breast cancer: A site-specific analysis of the prospective, phase-II RADIANT trial.
Ruicci KM, Helou J, Barry A, Ye XY, Koch CA, Croke J, Han K, Rodin D, Hahn E, Kwan JYY, Yan M, Liu FF, Lindsay P, Javor J, Bedard P, Cescon D, Kumar V, Amir E, Nadler MB, Lee R, Glicksman RM
FAM72A promotes UNG2 degradation and mutagenesis in human cancer cells.
Feng Y, Barbulescu P, Chana CK, Shirdarreh M, Yang H, Wu L, Mamand S, Kashem M, Zia A, Han M, Tsao J, Pugh T, Cescon D, Schatz DG, Sicheri F, Martin A, Pezo RC
Detection of metabolic adaptation in a triple-negative breast cancer animal model with [18F]choline-PET imaging as a surrogate for drug resistance.
Kohan AA, Lupien M, Cescon D, Deblois G, Ventura M, Metser U, Veit-Haibach P
Reply to Trudeau, M.; Fraser, B. The CADTH pCODR Expert Review Committee Process Explained. Comment on "Rayson et al. Access to Neoadjuvant Pertuzumab for HER2 Positive Breast Cancer in Canada: A Dilemma Increasingly Difficult to Explain. Curr. Oncol. 2022, 29, 9891-9895".
Rayson D, Gandhi S, Joy AA, Brezden-Masley C, Gelmon KA, Sehdev S, Cescon D, Chia S
Access to Neoadjuvant Pertuzumab for HER2 Positive Breast Cancer in Canada: A Dilemma Increasingly Difficult to Explain.
Rayson D, Gandhi S, Joy AA, Brezden-Masley C, Gelmon KA, Sehdev S, Cescon D, Chia S
If we build it they will come: targeting the immune response to breast cancer.
Gatti-Mays ME, Balko JM, Gameiro SR, Bear HD, Prabhakaran S, Fukui J, Disis ML, Nanda R, Gulley JL, Kalinsky K, Abdul Sater H, Sparano JA, Cescon D, Page DB, McArthur H, Adams S, Mittendorf EA
MicroSPECT/CT Imaging of Cell-Line and Patient-Derived EGFR-Positive Tumor Xenografts in Mice with Panitumumab Fab Modified with Hexahistidine Peptides To Enable Labeling with 99mTc(I) Tricarbonyl Complex.
Ku A, Chan C, Aghevlian S, Cai Z, Cescon D, Bratman SV, Ailles L, Hedley DW, Reilly RM
An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE).
Clouthier DL, Lien SC, Yang SYC, Nguyen LT, Manem VSK, Gray D, Ryczko M, Razak ARA, Lewin J, Lheureux S, Colombo I, Bedard PL, Cescon D, Spreafico A, Butler MO, Hansen AR, Jang RW, Ghai S, Weinreb I, Sotov V, Gadalla R, Noamani B, Guo M, Elston S, Giesler A, Hakgor S, Jiang H, McGaha T, Brooks DG, Haibe-Kains B, Pugh TJ, Ohashi PS, Siu LL
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro.
Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B
Gene isoforms as expression-based biomarkers predictive of drug response in vitro.
Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B
Rebooting Sensitivity to Checkpoint Blockade Therapy in TNBC (RESETT)
Principal investigators: Reedijk, Michael
Keywords: Caspase 1; Cytotoxic T Lymphocyte; Il1 Beta; Immune Checkpoint Blockade; Immunotherapy; Notch Signaling; Randomized Control Trial; Triple-Negative Breasat Cancer; Tumor Immune Microenvironment; Tumor-Associated Macrophage
Finding vulnerabilities in advanced breast cancer from the chromatin state of repeat DNA
Principal investigators: Lupien, Mathieu
Keywords: Breast Cancer; Chromatin; Epigenetic; Plasticity; Regulatory Elements; Repetitive Dna; Single-Cell Multiome; Transcription Factor; Transposable Elements
198Au-Nanodepot Combined with Adjuvant Auger Electron Radioimmunotherapy, Immunotherapy and Chemotherapy for Triple-Negative Breast Cancer in Metastatic Humanized Mouse Models
Principal investigators: Reilly, Raymond M
Keywords: 111in; 198au; Auger Electrons; Brachytherapy; Epidermal Growth Factor Receptor (Egfr); Humanized Mice; Immunotherapy; Radiation Nanomedicine; Radioimmunotherapy; Triple-Negative Breast Cancer
Finding vulnerabilities in breast cancer from the state of chromatin accessibility at transposable elements
Principal investigators: Lupien, Mathieu
Keywords: Breast Cancer; Chromatin; Epigenetic; Plasticity; Regulatory Elements; Repetitive Dna; Single-Cell Multiome; Transcription Factor; Transposable Elements
Defining genomic determinants of drug sensitivity and acquired resistance in triple negative breast cancer
Principal investigators: Elliott, Mitchell
Keywords: Breast Cancer; Dna Damage; Patient Derived Organoid Models; Patient Derived Xenograft Models; Structural Variants
Triple negative breast cancer intratumour heterogeneity and disease progression
Principal investigators: Done, Susan J
Keywords: Breast Cancer
Overcoming ER+ Breast Cancer with Fulvestrant-siRNA co-delivery
Principal investigators: Shoichet, Molly S
Keywords: Breast Cancer; Colloidal Drug Aggregates; Combination Drug Formulations; Endosomal Escape; Fulvestrant Analogues; Lipid Nanoparticles; Sirna Delivery
Development of TCR-engineered T cells against novel NY-ESO-1 epitopes for the treatment of triple negative breast cancer
Principal investigators: Hirano, Naoto; Cescon, David W
Keywords: Breast Cancer; Combination Therapy; Drug Development; Immunotherapy; Preclinical Models; Targeted Therapy; Tcr T Cells
Discovery and validation of vulnerabilities and therapeutic strategies for cyclin-dependent kinase 4/6 inhibitor-resistant hormone receptor positive breast cancer
Principal investigators: Cescon, David W
Keywords: Breast Cancer; Cell Cycle; Developmental Therapeutics; Drug Development; Drug Resistance; Functional Genomics; Preclinical Models
Chromatin context of somatic mutations delineate oncogenic drivers in triple-negative breast cancer
Principal investigators: Lupien, Mathieu
Keywords: Breast Cancer; Chromatin; Endocrine; Epigenetic; Gene Expression; Genetic; Genome; Mutations; Noncoding; Transcriptional Regulation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Medicine
- Department of Medical Biophysics
- Radiation Oncology/Medical Physics
- Medical Biophysics
- Immunology
- Institute of Health Policy, Management and Evaluation
- Radiation Oncology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Benjamin Haibe-Kains
Radiation Oncology/Medical Physics
3 shared papers, latest 2019
Mathieu Lupien
Medical Biophysics
3 shared papers, latest 2024
Kathy Han
Faculty
1 shared papers, latest 2026
Kelsie Thu
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2017
Danielle Rodin
Institute of Health Policy, Management and Evaluation
1 shared papers, latest 2026
Jennifer Croke
Faculty
1 shared papers, latest 2026
Stephanie Lheureux
Medical Oncology
1 shared papers, latest 2019
Eitan Amir
Department of Medicine
1 shared papers, latest 2026
Lily Zhou
Faculty
1 shared papers, latest 2013
Michael Yan
Faculty
1 shared papers, latest 2026
Philippe Bedard
Department of Medicine
1 shared papers, latest 2026
Patrick Veit-Haibach
Department of Medical Imaging
1 shared papers, latest 2024
Fei-Fei Liu
Radiation Oncology
1 shared papers, latest 2026
Samuel Aparicio
Molecular Oncology
1 shared papers, latest 2017
Laurie Ailles
Department of Medical Biophysics
1 shared papers, latest 2019
Jason Wong
Faculty
1 shared papers, latest 2017
Trevor Pugh
Department of Medical Biophysics
1 shared papers, latest 2025
Tracy McGaha
Faculty
1 shared papers, latest 2019
Anna Spreafico
Faculty
1 shared papers, latest 2019
Frank Sicheri
Lunenfeld-Tanenbaum Research Institute
1 shared papers, latest 2025
Chiara Gorrini
Faculty
1 shared papers, latest 2013
Alberto Martin
Immunology
1 shared papers, latest 2025
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