Faculty profile

Scott Gray-Owen

ResearcherMolecular GeneticsUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Scott Gray-Owen

Researcher

Molecular Genetics

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
1 publication in the last five years, latest in 2022.
Principal investigator on 13 research grants (13 CIHR), most recently in 2026.
Supervised 4 trainees who won CIHR awards, most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Gonorrhea Sexually Transmitted Infection Bacterial Infection Neisseria Gonorrhoeae Inflammation Innate Immunity Neisseria Biochemistry

Latest papers

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation
Viruses · 2022
Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing.
Journal of the American Chemical Society · 2021
The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils.
mBio · 2020

All 7 publications

Latest funding

CEACAM1-mediated immune suppression during neisserial infection
CIHR · 2026 · Nominated PI
$1,139,850
CEACAM Dynamics During Cell Adherence And Receptor-Dependent Engulfment
CIHR · 2025 · Co-investigator
$573,750
Heptose phosphate-mediated subversion of immunity by Neisseria gonorrhoeae
CIHR · 2024 · Nominated PI
$1,139,850

All 25 grants and awards

7 publications.

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation

Dahal S, Cheng R, Cheung PK, Been T, Malty R, Geng M, Manianis S, Shkreta L, Jahanshahi S, Toutant J

Viruses202220 citations

DOI: 10.3390/v14010060

Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing.

Yousefi H, Mahmud A, Chang D, Das J, Gomis S, Chen JB, Wang H, Been T, Yip L, Coomes E, Li Z, Mubareka S, McGeer A, Christie N, Gray-Owen S, Cochrane A, Rini JM, Sargent EH, Kelley SO

Journal of the American Chemical Society2021

DOI: 10.1021/jacs.0c10810 PMID: 33481575

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils.

Behrens IK, Busch B, Ishikawa-Ankerhold H, Palamides P, Shively JE, Stanners C, Chan C, Leung N, Gray-Owen S, Haas R

mBio2020

DOI: 10.1128/mbio.03256-19 PMID: 32019805

Murine Plasmodium chabaudi malaria increases mucosal immune activation and the expression of putative HIV susceptibility markers in the gut and genital mucosae.

Chege D, Higgins SJ, McDonald CR, Shahabi K, Huibner S, Kain T, Kain D, Kim CJ, Leung N, Amin M, Geddes K, Serghides L, Philpott DJ, Kimani J, Gray-Owen S, Kain KC, Kaul R

Journal of acquired immune deficiency syndromes (1999)2014

DOI: 10.1097/qai.0000000000000056 PMID: 24256632

Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease.

Leung E, Datti A, Cossette M, Goodreid J, McCaw SE, Mah M, Nakhamchik A, Ogata K, El Bakkouri M, Cheng YQ, Wodak SJ, Eger BT, Pai EF, Liu J, Gray-Owen S, Batey RA, Houry WA

Chemistry & biology2011

DOI: 10.1016/j.chembiol.2011.07.023 PMID: 21944755

Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy.

Wong R, Balachandran A, Mao AY, Dobson W, Gray-Owen S, Cochrane A

Retrovirology2011

DOI: 10.1186/1742-4690-8-47 PMID: 21682887

Mucosal Neisseria gonorrhoeae coinfection during HIV acquisition is associated with enhanced systemic HIV-specific CD8 T-cell responses.

Sheung A, Rebbapragada A, Shin LY, Dobson-Belaire W, Kimani J, Ngugi E, MacDonald KS, Bwayo JJ, Moses S, Gray-Owen S, Kaul R, Kibera HIV Study Group

AIDS (London, England)2008

DOI: 10.1097/qad.0b013e32830baf5e PMID: 18753933

CEACAM1-mediated immune suppression during neisserial infection

Nominated PICIHR2026Project Grant

Principal investigators: Gray-Owen, Scott D

Keywords: Bacterial Infection; Ceacam1; Gonorrhea; Immunity; Inflammation; Neisseria; Neisseria Gonorrhoeae; Sexually Transmitted Infections

$1,139,850

CEACAM Dynamics During Cell Adherence And Receptor-Dependent Engulfment

Co-investigatorCIHR2025Project Grant

Principal investigators: Yip, Christopher M

Keywords: Anisotropy; Dynamics; Fluorescence; Infection; Interactions; Membrane Receptors; Microscopy; Structure

$573,750

Heptose phosphate-mediated subversion of immunity by Neisseria gonorrhoeae

Nominated PICIHR2024Project Grant

Principal investigators: Gray-Owen, Scott D

Keywords: Bacterial Infection; Inflammation; Innate Immunity; Mouse Infection Models; Sexually Transmitted Infection

$1,139,850

Formulating a broadly cross-protective TbpB-based vaccine to combat Neisseria gonorrhoeae.

Nominated PICIHR2024Ca. Gr.: Biomedical Res. for HIV/AIDS/STBBI - Next-generation prev. technologies

Principal investigators: Gray-Owen, Scott D

Keywords: Bacterial Infection; Gonorrhea; Neisseria Gonorrhoeae; Sexually Transmitted Infection; Vaccine

$200,000

Canada Research Chair - Tier 1

Nominated PICIHR2021Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Gray-Owen, Scott D

Keywords: Cr

$1,400,000

Addressing gaps in our understanding of the mucosal immune response to SARS-CoV-2: Implications for transmission.

Co-investigatorCIHR2021Operating Grant: Emerging COVID-19 Research Gaps and Priorities - Vaccines

Principal investigators: Gommerman, Jennifer L

Keywords: Animal Models; Antibodies; B Cells; Immunology; Mucosal Immunity; Plasma Cells

Can COVID-19 and maternal antibodies to SARS-CoV-2 be transmitted through human milk? Implications for breastfeeding and human milk banking

Co-investigatorCIHR2020Op Gr: COVID-19 Rapid Research FO - Clinical Mgmt/Health System Interventions

Principal investigators: O'Connor, Deborah L; Poutanen, Susan M; Unger, Sharon

Keywords: Breastfeeding; Covid-19; Donor Human Milk; Human Milk; Milk Banking

$154,245

Rethinking the role of B cells in IgA nephropathy

Co-investigatorCIHR2020Project Grant

Principal investigators: Reich, Heather

Keywords: B Cells; Cytokine; Glomerulonephritis; Iga Nephropathy; Immunology; Kidney Disease

$596,700

29th Annual International CEA Symposium

Nominated PICIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Gray-Owen, Scott D

Keywords: Angiogenesis; Cancer; Carcinoembryonic Antigen (Cea); Cea-Related Cell Adhesion Molecules (Ceacams); Cell Signaling; Diabetes; Infectious Disease; Pregnancy-Specific Glycoproteins

$10,000

Overcoming drug resistance in gonorrhea through metabolic network analysis

Principal investigatorCIHR2018Project Grant

Principal investigators: Parkinson, John; Gray-Owen, Scott D

Keywords: Antimicrobial Resistance; Bioinformatics; Computational Biology; Constraints Based Modelling; Gonorrhea; Humanized Mouse Model; Metabolism; Population Genomics; Sexually Transmitted Infection; Systems Biology

$799,426

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Scott Gray-Owen

Research

Latest papers

Latest funding

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation

Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing.

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils.

Murine Plasmodium chabaudi malaria increases mucosal immune activation and the expression of putative HIV susceptibility markers in the gut and genital mucosae.

Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease.

Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy.

Mucosal Neisseria gonorrhoeae coinfection during HIV acquisition is associated with enhanced systemic HIV-specific CD8 T-cell responses.

CEACAM1-mediated immune suppression during neisserial infection

CEACAM Dynamics During Cell Adherence And Receptor-Dependent Engulfment

Heptose phosphate-mediated subversion of immunity by Neisseria gonorrhoeae

Formulating a broadly cross-protective TbpB-based vaccine to combat Neisseria gonorrhoeae.

Canada Research Chair - Tier 1

Addressing gaps in our understanding of the mucosal immune response to SARS-CoV-2: Implications for transmission.

Can COVID-19 and maternal antibodies to SARS-CoV-2 be transmitted through human milk? Implications for breastfeeding and human milk banking

Rethinking the role of B cells in IgA nephropathy

29th Annual International CEA Symposium

Overcoming drug resistance in gonorrhea through metabolic network analysis

Frequent collaborators

Alan Cochrane

Samira Mubareka

Rupert Kaul

Benoit Chabot

David Grierson

Lena Serghides

Karen Mossman

Allison McGeer

Mohan Babu

Jun Liu