Faculty profile
Steven Erwood
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Read how they describe their research on their University of Toronto profile.
Latest papers
Mutations in the β-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes.
Nature communications · 2025
Saturation variant interpretation using CRISPR prime editing.
Nature biotechnology · 2022 · first author
STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses
npj Genomic Medicine · 2021
Latest funding
- $910,350
Accurate classification of NPC1 variants with saturational genome editing
CIHR · 2021 · Co-investigator
8 publications.
Mutations in the β-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes.
Mollica A, Omer S, Forguson G, Steiman S, Evagelou SL, Naumenko S, Walker S, Li LY, Teeling A, Lindsay K, Erwood S, Visuvanathan S, Vig A, Vernon RM, Akman B, Smith-Hicks C, Forman-Kay JD, Shroff M, Pai V, Harrison RE, Cohn RD, Ivakine EA
Saturation variant interpretation using CRISPR prime editing.
Erwood S, Bily TMI, Lequyer J, Yan J, Gulati N, Brewer RA, Zhou L, Pelletier L, Ivakine EA, Cohn RD
STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses
Ori Scott, Kyle Lindsay, Steven Erwood, Antonio Mollica, Chaim M. Roifman, Ronald D. Cohn, Evgueni A. Ivakine
Allele-Specific Prevention of Nonsense-Mediated Decay in Cystic Fibrosis Using Homology-Independent Genome Editing
Steven Erwood, Onofrio Laselva, Teija M.I. Bily, Reid A. Brewer, Alexandra H. Rutherford, Christine E. Bear, Evgueni A. Ivakine
Embryo-Based Large Fragment Knock-in in Mammals: Why, How and What's Next.
Erwood S, Gu B
A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene
Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Elzbieta Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing
Bianca Garcı́a, Jooyoung Lee, Alireza Edraki, Yurima Hidalgo-Reyes, Steven Erwood, Aamir Mir, Chantel N. Trost, Uri Seroussi, Sabrina Y. Stanley, Ronald D. Cohn, Julie M. Claycomb, Erik J. Sontheimer, Karen L. Maxwell, Alan Richard Davidson
Modeling Niemann–Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation
Steven Erwood, Reid A. Brewer, Teija M.I. Bily, Eleonora Maino, Liangchi Zhou, Ronald D. Cohn, Evgueni A. Ivakine
Accurate classification of NPC1 variants with saturational genome editing
Principal investigators: Ivakine, Evgueni
Keywords: Crispr; Lysosomal Storage Disorders; Niemann Pick Disease Type C; Screen; Variants Of Unknown Significance
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Alan Davidson and Karen Maxwell: 70 shared papers
- Ronald Cohn and Evgueni Ivakine: 35 shared papers
- Rene Harrison and Safia Omer: 6 shared papers
- Ronald Cohn and Steven Erwood: 6 shared papers
- Evgueni Ivakine and Steven Erwood: 6 shared papers
- Manohar Shroff and Vivek Pai: 6 shared papers
- Alan Davidson and Julie Forman-Kay: 5 shared papers
- Evgueni Ivakine and Safia Omer: 4 shared papers
- Christine Bear and Julie Forman-Kay: 3 shared papers
- Laurence Pelletier and Ronald Cohn: 2 shared papers
- Laurence Pelletier and Evgueni Ivakine: 2 shared papers
- Julie Claycomb and Alan Davidson: 2 shared papers
- Julie Claycomb and Ronald Cohn: 2 shared papers
- Julie Claycomb and Karen Maxwell: 2 shared papers
- Rene Harrison and Julie Forman-Kay: 2 shared papers
- Rene Harrison and Ronald Cohn: 2 shared papers
- Julie Forman-Kay and Safia Omer: 2 shared papers
- Ronald Cohn and Karen Maxwell: 2 shared papers
- Laurence Pelletier and Steven Erwood: 1 shared paper
- Julie Claycomb and Steven Erwood: 1 shared paper
- Rene Harrison and Christine Bear: 1 shared paper
- Rene Harrison and Steven Erwood: 1 shared paper
- Rene Harrison and Manohar Shroff: 1 shared paper
- Rene Harrison and Vivek Pai: 1 shared paper
- Christine Bear and Evgueni Ivakine: 1 shared paper
- Christine Bear and Steven Erwood: 1 shared paper
- Alan Davidson and Steven Erwood: 1 shared paper
- Steven Prescott and Ronald Cohn: 1 shared paper
- Steven Prescott and Evgueni Ivakine: 1 shared paper
- Steven Prescott and Steven Erwood: 1 shared paper
- Julie Forman-Kay and Steven Erwood: 1 shared paper
- Julie Forman-Kay and Manohar Shroff: 1 shared paper
- Julie Forman-Kay and Vivek Pai: 1 shared paper
- Karen Maxwell and Steven Erwood: 1 shared paper
- Safia Omer and Steven Erwood: 1 shared paper
- Steven Erwood and Manohar Shroff: 1 shared paper
- Steven Erwood and Vivek Pai: 1 shared paper
- Department of Molecular Genetics
- Department of Biochemistry
- Department of Medical Imaging
- Department of Biological Sciences
- Department of Molecular and Cellular Biology
- Institute of Medical Science
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Evgueni Ivakine
Department of Molecular Genetics
6 shared papers, latest 2025
Ronald Cohn
Department of Molecular Genetics
6 shared papers, latest 2025
Manohar Shroff
Department of Medical Imaging
1 shared papers, latest 2025
Vivek Pai
Department of Medical Imaging
1 shared papers, latest 2025
Rene Harrison
Department of Biological Sciences
1 shared papers, latest 2025
Christine Bear
Department of Biochemistry
1 shared papers, latest 2020
Alan Davidson
Department of Molecular Genetics
1 shared papers, latest 2019
Steven Prescott
Institute of Medical Science
1 shared papers, latest 2019
Julie Forman-Kay
Department of Biochemistry
1 shared papers, latest 2025
Karen Maxwell
Department of Biochemistry
1 shared papers, latest 2019
Laurence Pelletier
Department of Molecular Genetics
1 shared papers, latest 2022
Safia Omer
Department of Molecular and Cellular Biology
1 shared papers, latest 2025
Julie Claycomb
Department of Molecular Genetics
1 shared papers, latest 2019
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.