Warren Lee, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Acute Lung Injury Atherosclerosis Cardiovascular Disease Endothelium Crc Bacterial Superinfection Influenza Lung Endothelium

Latest papers

Hyperchylomicronemia causes endothelial cell inflammation and increases atherosclerosis.
Research square · 2024
Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.
The Journal of clinical investigation · 2020
Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells.
Scientific reports · 2016

All 3 publications

Latest funding

Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)
CIHR · 2025 · Principal investigator
$657,901
Photoacoustics and Ultrasound for Acute Lung Injury
CIHR · 2025 · Supervisor
$120,000
Development of non-invasive and radiation-free imaging of lung injuries
SSHRC · 2024 · Co-investigator
$125,000

All 19 grants and awards

3 publications.

01

Hyperchylomicronemia causes endothelial cell inflammation and increases atherosclerosis.

Izquierdo MC, Cabodevilla AG, Basu D, Nasias D, Kanter JE, Ho W, Gjini J, Fisher EA, Kim J, Lee W, Bornfeldt KE, Goldberg IJ

Research square2024

DOI: 10.21203/rs.3.rs-5451391/v1 PMID: 39649171

02

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.

Siraj MA, Mundil D, Beca S, Momen A, Shikatani EA, Afroze T, Sun X, Liu Y, Ghaffari S, Lee W, Wheeler MB, Keller G, Backx P, Husain M

The Journal of clinical investigation2020

DOI: 10.1172/jci99934 PMID: 31985487

03

Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells.

Han B, Li M, Xu Y, Islam D, Khang J, Del Sorbo L, Lee W, Szaszi K, Zhong N, Slutsky AS, Li Y, Zhang H

Scientific reports2016

DOI: 10.1038/srep31087 PMID: 27506372

Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)

Principal investigatorCIHR2025Project Grant

Principal investigators: Hysi, Eno; Lee, Warren L

Keywords: Acute Respiratory Distress Syndrome; Biomarker Validation; Computed Tomography; Functional And Structural; Lung Injuries; Non-Ionizing; Oxygenation; Perfusion; Photoacoustic Imaging; Ultrasound Imaging

$657,901

Photoacoustics and Ultrasound for Acute Lung Injury

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Sauntharrajan, Babishaa

Keywords: Acute Respiratory Distress Syndrome; Biomarker Validation; Computed Tomography; Functional And Strucutral; Lung Injuries; Non-Ionizing; Oxygenation; Perfusion; Photoacoustic Imaging; Ultrasound Imaging

$120,000

Development of non-invasive and radiation-free imaging of lung injuries

Co-investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Hysi, Eno

$125,000

Deciphering the intracellular interactome of LDL during endothelial transcytosis - elucidating novel therapeutic targets for atherosclerosis

Nominated PICIHR2024Project Grant

Principal investigators: Lee, Warren L

Keywords: Atherosclerosis; Cardiovascular Disease; Endothelium; Lipoprotein; Transcytosis

$944,775

DLP-3D printer for next generation biomanufacturing of drug delivery vehicles, cell culture models, and bioreactors

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Tsai, Scott

Keywords: 3D Printing; Biomanufacturing; Lab-on-a-Chip; Microfabrication; Microfluidics

$45,585

Canada Research Chair - Tier 2

Nominated PICIHR2020Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Lee, Warren L

Keywords: Crc

$500,000

Regulation and function of Duffy antigen receptor for chemokines (DARC) in primary endothelial cells

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Lee, Warren

$252,000

Inflammation and LDL transcytosis - implications for early atherosclerosis

Nominated PICIHR2019Project Grant

Principal investigators: Lee, Warren L

Keywords: Atherosclerosis; Cardiovascular Disease; Endothelium; Inflammation; Lipoproteins

$810,900

Development of a lung ultrasound therapy system for acute respiratory distress syndrome

Principal investigatorNSERC2018Collaborative Health Research Projects

Principal investigators: Lee, Warren

$362,865

Mask aligner for a microfluidic soft lithography cleanroom

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Tsai, Scott

$148,447

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Medicine
Medical Biophysics
Anesthesia
Medicine
Biology
Department of Physiology
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Haibo Zhang

Anesthesia

1 shared papers, latest 2016

Katalin Szaszi

Faculty

1 shared papers, latest 2016

Peter Backx

Biology

1 shared papers, latest 2020

Lorenzo Del Sorbo

Faculty

1 shared papers, latest 2016

Gordon Keller

Medical Biophysics

1 shared papers, latest 2020

Mansoor Husain

Medicine

1 shared papers, latest 2020

Peter Backx

Department of Physiology

1 shared papers, latest 2020

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Acute Lung Injury Dear Professor Lee, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Hyperchylomicronemia causes endothelial cell inflammation and increases atherosclerosis." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Warren Lee

Research

Latest papers

Latest funding

Hyperchylomicronemia causes endothelial cell inflammation and increases atherosclerosis.

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-&#x3b1;.

Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells.

Photoacoustics And Ultrasound for Acute Lung Injury (PAULI)

Photoacoustics and Ultrasound for Acute Lung Injury

Development of non-invasive and radiation-free imaging of lung injuries

Deciphering the intracellular interactome of LDL during endothelial transcytosis - elucidating novel therapeutic targets for atherosclerosis

DLP-3D printer for next generation biomanufacturing of drug delivery vehicles, cell culture models, and bioreactors

Canada Research Chair - Tier 2

Regulation and function of Duffy antigen receptor for chemokines (DARC) in primary endothelial cells

Inflammation and LDL transcytosis - implications for early atherosclerosis

Development of a lung ultrasound therapy system for acute respiratory distress syndrome

Mask aligner for a microfluidic soft lithography cleanroom

Frequent collaborators

Haibo Zhang

Katalin Szaszi

Peter Backx

Lorenzo Del Sorbo

Gordon Keller

Mansoor Husain

Peter Backx

Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.