Faculty profile

Bryan Heit

ResearcherMicrobiology and ImmunologyWestern University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses may be missing. Find their university profile.

Bryan Heit

Researcher

Microbiology and Immunology

Health Sciences

Western University

London, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
10 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (4 CIHR, 2 NSERC), most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Atherosclerosis Inflammation Antigen Presentation Rab Gtpases Vesicular Trafficking Phagocytosis Estrogen Immunofluorescence

Latest papers

B-cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells.
Journal of immunology (Baltimore, Md. : 1950) · 2026
MERTK coordinates efferocytosis by regulating integrin localization and activation.
Journal of cell science · 2026 · senior author
GATA2 induces a stem cell-like transcriptional program in macrophages that promotes an atherogenic phenotype.
Journal of leukocyte biology · 2025 · senior author

All 44 publications

Latest funding

A Cardiac Rebound: Targeting GATA2 to Reverse Atherosclerosis
CIHR · 2026 · Nominated PI
$910,350
The role of immune responses to citrullinated and homocitrullinated proteins in rheumatoid arthritis-associated atherosclerosis
CIHR · 2025 · Co-investigator
$780,300
Guardians of Immunity: Investigating the Reciprocal Influence of Apoptotic Cells and Pathogens on MHC II Regulation and Vesicular Trafficking.
CIHR · 2024 · Nominated PI
$1,055,700

All 14 grants and awards

44 publications.

B-cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells.

Morelli DM, Langille M, Zhang R, Craig HC, Eltom Mohamed A, Shooshtari P, Heit B, Kerfoot SM

Journal of immunology (Baltimore, Md. : 1950)2026

DOI: 10.1093/jimmun/vkaf282 PMID: 41082629

MERTK coordinates efferocytosis by regulating integrin localization and activation.

Dickson BH, Tasnim T, Nicholson RA, Stanlake N, Lam AL, Vrieze AM, Blythe EN, Dekaban GA, Heit B

Journal of cell science2026Senior author

DOI: 10.1242/jcs.264792 PMID: 41716147

GATA2 induces a stem cell-like transcriptional program in macrophages that promotes an atherogenic phenotype.

Aktar A, Vrieze AM, Telesnicki K, Cox-Duvall P, Arbolino M, DeKoter RP, Nagpal AD, Heit B

Journal of leukocyte biology2025Senior author

DOI: 10.1093/jleuko/qiaf136 PMID: 40997212

GATA2 Mediates Macrophage Proliferation During Atherosclerosis.

Aktar A, Vrieze AM, Telesnicki K, Mun M, Wodz K, Yin C, Cox-Duvall P, Nagpal D, Heit B

Journal of the American Heart Association2025Senior author

DOI: 10.1161/jaha.125.043646 PMID: 41147413

Methods for Quantitative Efferocytosis Assays.

Taefehshokr N, Heit B

Methods in molecular biology (Clifton, N.J.)2023Senior author

DOI: 10.1007/978-1-0716-3338-0_4 PMID: 37365460

Role of the pioneer transcription factor GATA2 in health and disease.

Aktar A, Heit B

Journal of molecular medicine (Berlin, Germany)2023Senior author

DOI: 10.1007/s00109-023-02359-8 PMID: 37624387

Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis.

Del Sordo L, Blackler GB, Philpott HT, Riviere J, Gunaratnam L, Heit B, Appleton CT

Arthritis & rheumatology (Hoboken, N.J.)2023

DOI: 10.1002/art.42412 PMID: 36448607

Analysis of Efferocytic Receptor Dynamics and Synapse Formation in a Frustrated Efferocytosis Model.

Dickson BH, Heit B

Methods in molecular biology (Clifton, N.J.)2023Senior author

DOI: 10.1007/978-1-0716-3338-0_5 PMID: 37365461

Optimizing Long-Term Live Cell Imaging.

Lac A, Le Lam A, Heit B

Methods in molecular biology (Clifton, N.J.)2022Senior author

DOI: 10.1007/978-1-0716-2051-9_3 PMID: 35218532

Monitoring Cellular Responses to Infection with Fluorescent Biosensors.

Aktar A, Wodz KM, Heit B

Methods in molecular biology (Clifton, N.J.)2022Senior author

DOI: 10.1007/978-1-0716-2051-9_6 PMID: 35218535

A Cardiac Rebound: Targeting GATA2 to Reverse Atherosclerosis

Nominated PICIHR2026Project Grant

Principal investigators: Heit, Bryan J

Keywords: Atherosclerosis; Estrogen; Immunofluorescence; Macrophages; Plaque Development; Plaque Regression; Signaling; Transcription; Whole Animal Imaging

$910,350

The role of immune responses to citrullinated and homocitrullinated proteins in rheumatoid arthritis-associated atherosclerosis

Co-investigatorCIHR2025Project Grant

Principal investigators: Barra, Lillian

Keywords: Atherosclerosis; Autoantibodies; Biomarkers; Cytokines; Macrophages; Mouse Models; Post-Translational Modifications; Rheumatoid Arthritis; T Cells; Transcriptomics

$780,300

Guardians of Immunity: Investigating the Reciprocal Influence of Apoptotic Cells and Pathogens on MHC II Regulation and Vesicular Trafficking.

Nominated PICIHR2024Project Grant

Principal investigators: Heit, Bryan J

Keywords: Antigen Presentation; Apoptosis; Autoimmunity; Dendritic Cells; Inflammation; Major Histocompatibility Molecule Type Ii; Pathogens; Rab Gtpases; T Cell Activation; Vesicular Trafficking

$1,055,700

Multimodal Microplate Reader for Research in Microbiology and Immunology

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: McCormick, John

$149,160

Cages, Corrals and Vesicular Trafficking Shape the Diffusional Environment of the Plasma Membrane.

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Heit, Bryan

$120,000

Aging, exercise, and sex: impact on the pathophysiology of ventilation-induced lung injury

Co-investigatorCIHR2022Project Grant

Principal investigators: Gill, Sean E; Melling, Jamie; Veldhuizen, Rudolf A

Keywords: Acute Respiratory Distress Syndrome; Aging; Macrophages; Surfactant; Treadmill Running; Ventilation-Induced Lung Injury

$772,650

Aging and exercise: impact on the pathophysiology of ventilation-induced lung injury

Co-investigatorCIHR2021Project Grant - PA: Circulatory and Respiratory Health

Principal investigators: Gill, Sean E; Melling, Jamie; Veldhuizen, Rudolf A

Keywords: Acute Respiratory Distress Syndrome; Aging; Macrophages; Surfactant; Treadmill Running; Ventilation-Induced Lung Injury

$100,000

Smooth muscle cell diversity and thoracic aorta vulnerability

Co-investigatorCIHR2021Project Grant

Principal investigators: Pickering, J. Geoffrey

Keywords: Aorta; Senescence; Transcriptome; Vascular Smooth Muscle Cell

$852,975

Failing to Heal: Impaired Efferocytosis in Osteoarthritis

Co-investigatorCIHR2019Project Grant

Principal investigators: Appleton, Thomas C

Keywords: Cartilage; Efferocytosis; Gene Expression; Inflammation; Macrophage; Osteoarthritis; Phagocytosis; Synovium

$738,225

Role of ELKS1 and Rab17 in Differential Antigen Sorting and MHC II Trafficking Following Efferocytosis and Phagocytosis

Nominated PICIHR2018Project Grant

Principal investigators: Heit, Bryan J

Keywords: Antigen Presentation; Antigen Processing; Cell Signaling; Efferocyotsis; Immune Activation; Mhc Ii Loading Compartment; Phagocytosis; Rab Gtpases; Tlr Signaling; Vesicular Trafficking

$776,475

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Bryan Heit

Research

Latest papers

Latest funding

B-cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells.

MERTK coordinates efferocytosis by regulating integrin localization and activation.

GATA2 induces a stem cell-like transcriptional program in macrophages that promotes an atherogenic phenotype.

GATA2 Mediates Macrophage Proliferation During Atherosclerosis.

Methods for Quantitative Efferocytosis Assays.

Role of the pioneer transcription factor GATA2 in health and disease.

Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis.

Analysis of Efferocytic Receptor Dynamics and Synapse Formation in a Frustrated Efferocytosis Model.

Optimizing Long-Term Live Cell Imaging.

Monitoring Cellular Responses to Infection with Fluorescent Biosensors.

A Cardiac Rebound: Targeting GATA2 to Reverse Atherosclerosis

The role of immune responses to citrullinated and homocitrullinated proteins in rheumatoid arthritis-associated atherosclerosis

Guardians of Immunity: Investigating the Reciprocal Influence of Apoptotic Cells and Pathogens on MHC II Regulation and Vesicular Trafficking.

Multimodal Microplate Reader for Research in Microbiology and Immunology

Cages, Corrals and Vesicular Trafficking Shape the Diffusional Environment of the Plasma Membrane.

Aging, exercise, and sex: impact on the pathophysiology of ventilation-induced lung injury

Aging and exercise: impact on the pathophysiology of ventilation-induced lung injury

Smooth muscle cell diversity and thoracic aorta vulnerability

Failing to Heal: Impaired Efferocytosis in Osteoarthritis

Role of ELKS1 and Rab17 in Differential Antigen Sorting and MHC II Trafficking Following Efferocytosis and Phagocytosis

Frequent collaborators

Amira Klip

Jun Liu

Gregory Fairn

Lakshman Gunaratnam

Lina Dagnino

Lillian Barra

Parisa Shooshtari

Maria Febbraio

Sergio Grinstein

Dawn Bowdish

Brian Golding