Faculty profile
David Hess
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Read how they describe their research on their Western University profile.
Latest papers
Cardiometabolic risk management: insights from a European Society of Cardiology Cardiovascular Round Table.
European heart journal · 2023
Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes.
Neoplasia (New York, N.Y.) · 2021
Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.
BMC cancer · 2019
Latest funding
- $100,000
Novel Mechanisms in Doxorubicin-induced Cardiomyopathy
CIHR · 2025 · Principal investigator
- $100,000
Novel Mechanisms in Doxorubicin-induced Cardiomyopathy
CIHR · 2024 · Principal investigator
- $1,021,276
Delivery of human monocytes and adipose-derived stromal cells within decellularized adipose tissue hydrogels for peripheral vascular regeneration
CIHR · 2024 · Co-investigator
6 publications.
Cardiometabolic risk management: insights from a European Society of Cardiology Cardiovascular Round Table.
Cosentino F, Verma S, Ambery P, Treppendahl MB, van Eickels M, Anker SD, Cecchini M, Fioretto P, Groop PH, Hess D, Khunti K, Lam CSP, Richard-Lordereau I, Lund LH, McGreavy P, Newsome PN, Sattar N, Solomon S, Weidinger F, Zannad F, Zeiher A
Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes.
Dieters-Castator D, Dantonio PM, Piaseczny M, Zhang G, Liu J, Kuljanin M, Sherman S, Jewer M, Quesnel K, Kang EY, Köbel M, Siegers GM, Leask A, Hess D, Lajoie G, Postovit LM
Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.
Tordjman J, Majumder M, Amiri M, Hasan A, Hess D, Lala PK
COX-2 induces oncogenic micro RNA miR655 in human breast cancer.
Majumder M, Dunn L, Liu L, Hasan A, Vincent K, Brackstone M, Hess D, Lala PK
COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.
Majumder M, Xin X, Liu L, Tutunea-Fatan E, Rodriguez-Torres M, Vincent K, Postovit LM, Hess D, Lala PK
COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation.
Majumder M, Landman E, Liu L, Hess D, Lala PK
Novel Mechanisms in Doxorubicin-induced Cardiomyopathy
Principal investigators: Singh, Krishna K; Hess, David A
Keywords: Breast Cancer Susceptibility Gene; Doxorubicin; Heart Failure
Novel Mechanisms in Doxorubicin-induced Cardiomyopathy
Principal investigators: Singh, Krishna K; Hess, David A
Keywords: Breast Cancer Susceptibility Gene 2; Doxorubicin; Heart Failure
Delivery of human monocytes and adipose-derived stromal cells within decellularized adipose tissue hydrogels for peripheral vascular regeneration
Principal investigators: Flynn, Lauren E
Keywords: Adipose-Derived Stromal Cells; Bioscaffolds; Cell Therapy; Critical Limb Ischemia; Diabetes; Immunomodulation; In Vivo Imaging; Monocytes; Peripheral Artery Disease; Vascular Regeneration
Novel Mechanisms in Doxorubicin-induced Cardiomyopathy
Principal investigators: Singh, Krishna K; Hess, David A
Keywords: Breast Cancer Susceptibility Gene 2; Doxorubicin; Heart Failure
Development of a Novel Therapy to Prevent Breast Cancer Metastasis: Modulation of TAFI, a Master Regulator of Extracellular Proteolysis
Principal investigators: Boffa, Michael B
Keywords: Breast Cancer; Extracellular Proteolysis; Metastasis; Mouse Models; Thrombin-Activatable Fibrinolysis Inhibitor (Tafi); Thrombomodulin
Formation of an islet regenerative niche using human mesenchymal stem cell secreted signals
Principal investigators: Hess, David A
Keywords: Beta Cell Proliferation; Diabetes; Human Islet Culture; Human Mesenchymal Stem Cells; Islet Neogenesis; Islet Regeneration; Quantitative Proteomics; Secretome Analyses; Transplantation; Wnt-Signalling
Formulation of a vascular regenerative niche within implantable human decellularized adipose tissue bioscaffolds
Principal investigators: Hess, David A
Keywords: Angiogenesis; Arteriogenesis; Critical Limb Ischemia; Decellularized Adipose Tissue; Endothelial Progenitor Cells; Hematopoietic Progenitor Cells; Multipotent Stromal Cells; Peripheral Artery Disease; Umbilical Cord Blood Stem Cells; Vasculogenesis
Characterization of human umbilical cord blood progenitor cells for vascular regeneration
Principal investigators: Putman, David M
Keywords: Aldehyde Dehydrogenase; Critical Limb Ischemia; Hindlimb Ischemia; Peripheral Vascular Disease; Regenerative Medicine; Stem And Progenitor Cells; Transplantation; Umbilical Cord Blood; Vascular Regeneration
Placental mesenchymal stem cells in regenerative therapy
Principal investigators: Han, Victor Khin M
Keywords: Cell Signaling; Cerebral Ischemia; Diabetes; Insulin-Like Growth Factors; Mesenchymal Stem Cells; Placenta; Regenerative Therapy; Tissue Environment; Tumorigenesis; Umbilical Cord Blood
Directed production of hESC-derived beta cell precursors for diabetes therapy.
Principal investigators: Hess, David A; Foster, Paula J; Hill, David J; Séguin, Cheryle A
Keywords: Beta Cell Regeneration; Diabetes; Human Embryonic Stem Cells; Mesenchymal Stromal Cells; Nanoparticle Cell Labeling; Transplantation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Physiology and Pharmacology
- Oncology
- Dentistry
- Cardiac Surgery
- Biomedical and Molecular Sciences
- Anesthesiology
- Other
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Mousumi Majumder
Faculty
2 shared papers, latest 2019
Lynne-Marie Postovit
Oncology
2 shared papers, latest 2021
Lynne-Marie Postovit
Biomedical and Molecular Sciences
1 shared papers, latest 2021
David Hess
Cardiac Surgery
1 shared papers, latest 2023
Andrew Leask
Dentistry
1 shared papers, latest 2021
Subodh Verma
Anesthesiology
1 shared papers, latest 2023
Muriel Brackstone
Faculty
1 shared papers, latest 2018
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Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.