Qingping Feng, Western University

Research

Read how they describe their research on their Western University profile.

Covid-19 Infection Inflammation Calcium Handling Heart Failure Myocardial Infarction Nitric Oxide

Latest papers

Haploinsufficiency of Endothelial Nitric Oxide Synthase Mitigates Beneficial Effects of Maternal Exercise on Fetal Heart Development During Pregestational Diabetes.
Journal of the American Heart Association · 2026 · senior author
Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition.
Scientific reports · 2026
Understanding the role of Shroom3 in the developing mouse myocardium.
PloS one · 2025

All 90 publications

Latest funding

Annexin A5 as a treatment for COVID-19
CIHR · 2021 · Nominated PI
$849,150
Microscale thermophoresis for assessing diverse molecular interactions.
NSERC · 2020 · Co-investigator
$150,000
Cell polarity and embryonic heart development
NSERC · 2017 · Principal investigator
$196,000

All 6 grants and awards

90 publications.

01

Haploinsufficiency of Endothelial Nitric Oxide Synthase Mitigates Beneficial Effects of Maternal Exercise on Fetal Heart Development During Pregestational Diabetes.

Van Neck R, Lu X, Pan T, Du I, Wisse LJ, DeRuiter MC, Feng Q

Journal of the American Heart Association2026Senior author

DOI: 10.1161/jaha.125.042848 PMID: 41467401

02

Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition.

Chandrabalan A, Lin QT, Fariha KA, Solis-Reyes P, Richer CG, Troyer RM, Barr SD, Feng Q, Stathopulos PB

Scientific reports2026

DOI: 10.1038/s41598-026-58451-9 PMID: 42323371

03

Understanding the role of Shroom3 in the developing mouse myocardium.

Carleton JL, Halabi RR, Willson JA, Plageman TF, Bridgewater D, Feng Q, Drysdale TA

PloS one2025

DOI: 10.1371/journal.pone.0331583 PMID: 40920782

04

SARS-CoV-2 Nucleocapsid Protein Does Not Induce Inflammation in Endothelial Cells or Monocytes.

Tufail M, Lu X, Barr SD, Borradaile N, Feng Q

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2025Senior author

DOI: 10.1096/fj.202501433r PMID: 41123875

05

Neuronal Nitric Oxide Synthase Regulates Cerebellar Parallel Fiber Slow EPSC in Purkinje Neurons by Modulating STIM1-Gated TRPC3-Containing Channels.

Gui L, Tellios V, Xiang YY, Feng Q, Inoue W, Lu WY

Cerebellum (London, England)2024

DOI: 10.1007/s12311-024-01683-0 PMID: 38472628

06

Maternal Delta-9-Tetrahydrocannabinol Exposure Induces Abnormalities of the Developing Heart in Mice.

Robinson GI, Ye F, Lu X, Laviolette SR, Feng Q

Cannabis and cannabinoid research2024Senior author

DOI: 10.1089/can.2022.0180 PMID: 36255470

07

Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction.

Nguyen HC, Bu S, Nikfarjam S, Rasheed B, Michels DCR, Singh A, Singh S, Marszal C, McGuire JJ, Feng Q, Frisbee JC, Qadura M, Singh KK

The Journal of biological chemistry2023

DOI: 10.1016/j.jbc.2023.102921 PMID: 36681124

08

Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19.

Tschirhart BJ, Lu X, Mokale Kognou AL, Martin CM, Slessarev M, Fraser DD, Leligdowicz A, Urquhart B, Feng Q

Frontiers in pharmacology2023Senior author

DOI: 10.3389/fphar.2023.1299613 PMID: 38269269

09

Annexin A5 in Patients With Severe COVID-19 Disease: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Feasibility Trial.

Martin CM, Slessarev M, Campbell E, Basmaji J, Ball I, Fraser DD, Leligdowicz A, Mele T, Priestap F, Tschirhart BJ, Bentall T, Lu X, Feng Q

Critical care explorations2023Senior author

DOI: 10.1097/cce.0000000000000986 PMID: 37811130

10

Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding.

Tschirhart BJ, Lu X, Gomes J, Chandrabalan A, Bell G, Hess DA, Xing G, Ling H, Burger D, Feng Q

Pharmaceuticals (Basel, Switzerland)2023Senior author

DOI: 10.3390/ph16060837 PMID: 37375784

Annexin A5 as a treatment for COVID-19

Nominated PICIHR2021Project Grant

Principal investigators: Feng, Qingping; Barr, Stephen D; Stathopulos, Peter B

Keywords: Covid-19; Infection; Inflammation

$849,150

Microscale thermophoresis for assessing diverse molecular interactions.

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Stathopulos, Peter

$150,000

Cell polarity and embryonic heart development

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Feng, Qingping

$196,000

nNOS regulates store-operated calcium entry in cardiomyocytes

Nominated PICIHR2015Operating Grant

Principal investigators: Feng, Qingping

Keywords: Calcium Handling; Heart Failure; Myocardial Infarction; Nitric Oxide

$677,721

Cardiac Repair by the Epicardium

Nominated PICIHR2011Operating Grant

Principal investigators: Feng, Qingping

Keywords: Cardiac Remodeling; Cardiac Repair; Heart Failure; Myocardial Infarction; Neovascularization; Stem Cells

$291,114

Rac1 Signaling in Myocardial TNF-alpha Expression in Sepsis

Nominated PICIHR2008Operating Grant

Principal investigators: Feng, Qingping

Keywords: Lipopolysaccharide; Nitric Oxide; Sepsis; Signal Transduction; Tumor Necrosis Factor-Alpha

$706,487

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Physiology and Pharmacology
Department of Physiology and Pharmacology
Pathology and Laboratory Medicine
Department of Medical Biophysics
Medicine
Cellular and Molecular Medicine
Biochemistry
Other

Applying for

Paper to mentionMention their CIHR grant from 2021

Subject: Prospective PhD student: Covid-19 Dear Professor Feng, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Haploinsufficiency of Endothelial Nitric Oxide Synthase Mitigates Beneficial Effects of Maternal Exercise on Fetal Heart Development During Pregestational Diabetes." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Annexin A5 as a treatment for COVID-19" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Qingping Feng

Research

Latest papers

Latest funding

Haploinsufficiency of Endothelial Nitric Oxide Synthase Mitigates Beneficial Effects of Maternal Exercise on Fetal Heart Development During Pregestational Diabetes.

Dual engagement of Spike and ACE2 by annexin A5 contributes to pleiotropic SARS-CoV-2 inhibition.

Understanding the role of Shroom3 in the developing mouse myocardium.

SARS-CoV-2 Nucleocapsid Protein Does Not Induce Inflammation in Endothelial Cells or Monocytes.

Neuronal Nitric Oxide Synthase Regulates Cerebellar Parallel Fiber Slow EPSC in Purkinje Neurons by Modulating STIM1-Gated TRPC3-Containing Channels.

Maternal Delta-9-Tetrahydrocannabinol Exposure Induces Abnormalities of the Developing Heart in Mice.

Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction.

Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19.

Annexin A5 in Patients With Severe COVID-19 Disease: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Feasibility Trial.

Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding.

Annexin A5 as a treatment for COVID-19

Microscale thermophoresis for assessing diverse molecular interactions.

Cell polarity and embryonic heart development

nNOS regulates store-operated calcium entry in cardiomyocytes

Cardiac Repair by the Epicardium

Rac1 Signaling in Myocardial TNF-alpha Expression in Sepsis

Frequent collaborators

Tianqing Peng

Peter Chidiac

Frank Beier

Robert Gros

Karel Tyml

Wei-Yang Lu

Marat Slessarev

Maria Drangova

James Koropatnick

Amin Rizkalla

Subrata Chakrabarti

Tina Mele

Mohammad Qadura

Ian Ball

Wataru Inoue

Kibret Mequanint

Nica Borradaile

Bradley Urquhart

Hong Ling

Na Li

Dylan Burger

Morris Karmazyn

Mitsuhiko Ikura