Faculty profile

Jacques Genest

ResearcherCardiologyMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Jacques Genest

Researcher

Cardiology

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
34 publications in the last five years, latest in 2026.
Senior (last) author on 10 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2019.
Supervised 2 trainees who won CIHR awards, most recently in 2008.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

173

Publications

3,651

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Cholesterol Familial Hypercholesterolemia Genetics Low Density Lipoproteins Abca1 Transporter Atherosclerosis Desmocollin 1 High Density Lipoproteins

Latest papers

Homozygous familial hypercholesterolemia (HoFH) in Canada.
Atherosclerosis · 2026
Familial Hypercholesterolemia.
Methodist DeBakey cardiovascular journal · 2026 · senior author
Predictors of aortic stenosis in homozygous familial hypercholesterolemia: A study from the Canadian HoFH registry.
Journal of clinical lipidology · 2026

All 173 publications

Latest funding

Familial Hypercholesterolemia in Canada: Precision and Personalized Approaches to Increase Identification and Improve Clinical outcomes
CIHR · 2019 · Nominated PI
$734,400
Homozygous Familial Hypercholesterolemia (HoFH) in Canada
CIHR · 2019 · Nominated PI
$99,617
Desmocollin 1 (DSC1) and atherosclerosis
CIHR · 2019 · Nominated PI
$765,000

All 14 grants and awards

From the 150 most recent of 173 publications.

Homozygous familial hypercholesterolemia (HoFH) in Canada.

Al-Baldawi Z, Erzingatzian A, Ruel I, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Paquette M, Baass A, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Moulson N, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Cifra B, Ransom T, McPherson R, Genest J, Brunham LR, Iatan I

Atherosclerosis2026

DOI: 10.1016/j.atherosclerosis.2026.120792 PMID: 42229223

Familial Hypercholesterolemia.

Iatan I, Genest J

Methodist DeBakey cardiovascular journal2026Senior author

DOI: 10.14797/mdcvj.1860 PMID: 42761917

Predictors of aortic stenosis in homozygous familial hypercholesterolemia: A study from the Canadian HoFH registry.

Paquette M, Erzingatzian A, Ruel I, Al-Baldawi Z, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Moulson N, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Cifra B, Ransom T, McPherson R, Genest J, Brunham LR, Iatan I, Baass A

Journal of clinical lipidology2026

DOI: 10.1016/j.jacl.2026.08.023 PMID: 42754461

Integration of a polygenic score into clinical risk prediction of atherosclerotic cardiovascular disease in familial hypercholesterolemia.

Paquette M, Trinder M, Ruel I, Guay SP, Hegele RA, Genest J, Brunham LR, Baass A

European journal of preventive cardiology2026

DOI: 10.1093/eurjpc/zwag203 PMID: 41983333

Assessment of LDL receptor-dependent lipid lowering therapies in patients with homozygous familial hypercholesterolemia according to functional genotype.

Mancini GBJ, Ryomoto A, Ruel I, Iatan I, Genest J, Raal FJ, Santos RD, Marte AP, Kennedy BA, Brunham LR, Gaudet D, Larouche M, Brisson D, Hegele RA, Canadian Homozygous Familial Hypercholesterolemia - HoFH Registry

Atherosclerosis2026

DOI: 10.1016/j.atherosclerosis.2026.120646 PMID: 41643340

Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry.

Erzingatzian A, Al-Baldawi Z, Ruel I, Brown L, Sherman MH, Laflamme N, Bergeron J, Couture P, Paquette M, Baass A, Brisson D, Larouche M, Gaudet D, Cermakova L, Wan D, Brunham LR, Francis GA, Mancini GBJ, Kennedy BA, Hegele RA, Lewis GF, McCrindle BW, Ransom T, McPherson R, Piazza N, de Varennes B, Genest J, Iatan I

JACC. Advances2026

DOI: 10.1016/j.jacadv.2025.102505 PMID: 41579830

Imputation of untreated LDL-C in treated subjects with homozygous familial hypercholesterolaemia: An international collaboration.

John Mancini GB, Ryomoto A, Ruel I, Iatan I, Raal FJ, Santos RD, Marte AP, Hegele RA, Kennedy BA, Brunham LR, Gaudet D, Larouche M, Brisson D, Schonck W, Reeskamp LF, Genest J, Canadian Homozygous Familial Hypercholesterolemia Registry and the Homozygous Familial Hypercholesterolemia International Clinical Collaboration

Atherosclerosis2026Senior author

DOI: 10.1016/j.atherosclerosis.2025.120590 PMID: 41275595

Extreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemia.

Paquette M, Ruel I, Guay SP, Al-Baldawi Z, Brisson D, Gaudet D, Couture P, Bergeron J, Hegele RA, Francis GA, Sherman MH, McPherson R, Ransom T, Brunham LR, Mancini GJ, McCrindle BW, Latan L, Genest J, Baass A

Journal of clinical lipidology2025

DOI: 10.1016/j.jacl.2024.10.008 PMID: 39638644

Polygenic risk score for coronary artery disease predicts atherosclerotic cardiovascular disease in familial hypercholesterolemia.

Paquette M, Trinder M, Ruel I, Guay SP, Hegele RA, Genest J, Brunham LR, Baass A

Journal of clinical lipidology2025

DOI: 10.1016/j.jacl.2025.01.004 PMID: 40000284

Low-Dose Docetaxel Is Effective in Reducing Atherogenic Lipids and Atherosclerosis.

Choi HY, Ruel I, Choi S, Iatan I, Choi S, Lee JY, Genest J

International journal of molecular sciences2025Senior author

DOI: 10.3390/ijms26041484 PMID: 40003949

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Jacques Genest

Research

Latest papers

Latest funding

Homozygous familial hypercholesterolemia (HoFH) in Canada.

Familial Hypercholesterolemia.

Predictors of aortic stenosis in homozygous familial hypercholesterolemia: A study from the Canadian HoFH registry.

Integration of a polygenic score into clinical risk prediction of atherosclerotic cardiovascular disease in familial hypercholesterolemia.

Assessment of LDL receptor-dependent lipid lowering therapies in patients with homozygous familial hypercholesterolemia according to functional genotype.

Aortic Stenosis in Homozygous Familial Hypercholesterolemia: The Canadian HoFH Registry.

Imputation of untreated LDL-C in treated subjects with homozygous familial hypercholesterolaemia: An international collaboration.

Extreme LDL-C concentration is associated with increased cardiovascular disease in women with homozygous familial hypercholesterolemia.

Polygenic risk score for coronary artery disease predicts atherosclerotic cardiovascular disease in familial hypercholesterolemia.

Low-Dose Docetaxel Is Effective in Reducing Atherogenic Lipids and Atherosclerosis.

Frequent collaborators

Patrick Couture

Ruth McPherson

Eva Lonn

Adel Schwertani

Sophie Bernard

George Thanassoulis

Louise Pilote

Louise Pilote

Rima Rozen

Lawrence Joseph

Paul Poirier

Steven Grover

Nadia Giannetti

Todd Anderson

Guillaume Pare

Minna Woo

Annik Prat

Julie St-Pierre

David Goltzman

Natalie Dayan

James Brophy

Walid Mourad

Jean-Philippe Drouin-Chartier

Thao Huynh

Maneesh Sud

Robert Platt

Michel Tremblay