Faculty profile

Louis Collins

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ProfessorDepartment of Biomedical EngineeringMcGill University

Louis Collins

Professor

Department of Biomedical Engineering

Faculty of Medicine and Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
157 publications in the last five years, latest in 2026.
Senior (last) author on 59 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 NSERC), most recently in 2015.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

1,058

Publications

68,320

Citations

365

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their McGill University profile.

Latest papers

Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline.
JAMA neurology · 2026
Human cortical organoids recapitulate inter-individual variability in infant brain-growth trajectories.
Cell stem cell · 2026
Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition.
GeroScience · 2026

All 1,058 publications

Latest funding

The McConnell Brain Imaging Center: A world-renowned multidisciplinary platform dedicated to brain research using multimodal neuroimaging and neuroinformatics
BRAIN · 2021 · Co-investigator
$4,674,000
Framework for multi-feature registration of medical images
NSERC · 2015 · Principal investigator
$120,000
CBRAIN: Canadian Brain Research And Informatics Platform
BRAIN · 2015 · Co-investigator
$2,775,000

All 15 grants and awards

From the 150 most recent of 1,058 publications.

Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline.

Coughlan GT, Ourry V, Townsend D, Klinger H, Brown JA, Cuppels M, Betthauser T, Langhough R, Cody K, Seto M, Birkenbihl C, Li A, Farrell M, Thibault E, Kivisäkk Webb P, Arnold S, Rissman RA, Properzi M, Schultz A, Johnson K, Langford O, Donohue MC, Villeneuve S, Johnson SC, Yang HS, Manson JE, Sperling R, Buckley RF, A4 Study Team, the Alzheimer’s Disease Neuroimaging Initiative, and the PREVENT-AD Research Group

JAMA neurology20267 citationsOpen Access

DOI: 10.1001/jamaneurol.2025.5670 PMID: 41697669

Human cortical organoids recapitulate inter-individual variability in infant brain-growth trajectories.

Glass MR, Matoba N, Beltran AA, Patel NK, Farah TM, Eswar K, Bhargava S, Huang K, Curtin I, Ahmed S, Srivastava M, Drake E, Davis LT, Yeturi M, Sun K, Love MI, Simon JM, John TS, Marrus N, Pandey J, Estes A, Dager S, Schultz RT, Botteron K, Evans A, Kim SH, Styner M, McKinstry RC, Collins DL, Volk H, Benke K, Zwaigenbaum L, Hazlett H, Beltran AS, Girault JB, Shen MD, Piven J, Stein JL, Infant Brain Imaging Study Network

Cell stem cell20263 citationsOpen Access

DOI: 10.1016/j.stem.2025.12.001 PMID: 41435817

Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition.

Potvin-Jutras Z, Tremblay PL, Mohammadi H, Villeneuve S, Spreng RN, Gauthier CJ, PREVENT-AD Research Group

GeroScience20262 citations

DOI: 10.1007/s11357-025-02036-3 PMID: 41353310

A digital twin methodology using retrospective patient data for sample size reduction in Alzheimer's disease clinical trials.

Andrews D, Golchi S, Collins DL, Alzheimer’s Disease Neuroimaging Initiative

Alzheimer's research & therapy20261 citationsOpen Access

DOI: 10.1186/s13195-026-02024-5 PMID: 42046101

Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.

Hosseini SA, Aumont E, Rahmouni N, Woo MS, Macedo AC, Hall B, Chan T, Therriault J, Trudel L, Zheng Y, Bezgin G, Lebrun A, Arias JF, Socualaya KQ, Tissot C, Servaes S, Wang YT, Oliva-Lopez D, Mitchell S, Hopewell R, Hsiao CH, Saleh C, Stevenson J, Lussier F, Wu L, Chu M, Chawla S, Fonov V, Massarweh G, Medina YI, Soucy JP, Provost K, Rudko DA, Karikari T, Benedet AL, Ashton NJ, Zetterberg H, Montembeault M, Vitali P, Blennow K, Gauthier S, Collins DL, Klostranec J, Pascoal TA, Rosa-Neto P

Alzheimer's & dementia : the journal of the Alzheimer's Association20261 citationsOpen Access

DOI: 10.1002/alz.71205 PMID: 41738400

Hippocampal-to-Ventricle Ratio as a Head-Size-Independent Biomarker: Sex Differences and Cognitive Associations in 27,680 UK Biobank Participants

Sofia Fernandez‐Lozano, D. Louis Collins

bioRxiv (Cold Spring Harbor Laboratory)20261 citationsSenior authorOpen Access

DOI: 10.64898/2026.04.13.718285

DeformView: Quantitative Visualization of Non-Linear Deformation Fields

Isabel Frolick, Elise Donszelmann-Lund, Taj Choksi, Étienne Léger, Raphaël Christin, Kaleem Siddiqi, D. Louis Collins

Zenodo (CERN European Organization for Nuclear Research)2026Senior authorOpen Access

DOI: 10.5281/zenodo.19008733

Sex Differences in the Alzheimer’s Brain Age Gap: APOE ε4 Plays a Major Role

Reza Rajabli, Mahdie Soltaninejad, Sylvia Villeneuve, D. Louis Collins

medRxiv2026Senior authorOpen Access

DOI: 10.64898/2026.07.13.26357678

DeformView: Quantitative Visualization of Non-Linear Deformation Fields

Isabel Frolick, Elise Donszelmann-Lund, Taj Choksi, Étienne Léger, Raphaël Christin, Kaleem Siddiqi, D. Louis Collins

Zenodo (CERN European Organization for Nuclear Research)2026Senior authorOpen Access

DOI: 10.5281/zenodo.21287630

Brain age estimation pipeline: trained weights and Apptainer image (Rajabli et al., 2025)

Reza Rajabli, Mahdie Soltaninejad, Vladimir Fonov, Danilo Bzdok, D. Louis Collins

Zenodo (CERN European Organization for Nuclear Research)2026Senior authorOpen Access

DOI: 10.5281/zenodo.20684408

The McConnell Brain Imaging Center: A world-renowned multidisciplinary platform dedicated to brain research using multimodal neuroimaging and neuroinformatics

Co-investigatorBRAIN20212019 Platform Support Grants

Principal investigators: Misic, Bratislav; Doyon, Julien; Baillet, Sylvain; Villeneuve, Sylvia

Keywords: Neurotechnology; Other

$4,674,000

Framework for multi-feature registration of medical images

Principal investigatorNSERC2015Discovery Grants Program - Accelerator Supplements

Principal investigators: Collins, Louis

$120,000

CBRAIN: Canadian Brain Research And Informatics Platform

Co-investigatorBRAIN20152014 Platform Grants

Principal investigators: Evans, Alan; Lerch, Jason

Keywords: Neurotechnology; Other

$2,775,000

Drug Delivery across the Human Blood-Brain Barrier

Co-investigatorBRAIN2015CQDM - Brain Canada - Focus on Brain

Principal investigators: Yoganathan, Nathan

Keywords: Neurodegeneration; Alzheimer's

$1,496,800

Optical guidance for safe and effective brain tumor biopsy

Co-investigatorNSERC2014Collaborative Health Research Projects

Principal investigators: Leblond, Frederic

$211,407

Réseaux structurels et fonctionnels dans les troubles du spectre de l’autisme et le syndrome de l’X fragile

Co-investigatorBRAIN2014Azrieli Neurodevelopment Research Program

Principal investigators: Evans, Alan; Zwaigenbaum, Lonnie

Keywords: Neurodevelopment

$2,492,735

NSERC CREATE: Medical Physics Research Training Network (MPRTN)

Co-investigatorNSERC2013Collaborative Research and Training Experience

Principal investigators: Seuntjens, Jan

$1,650,000

NSERC CREATE Program in Medical Image Analysis

Co-investigatorNSERC2012Collaborative Research and Training Experience

Principal investigators: Siddiqi, Kaleem

$1,650,000

Probabilistic segmentation of multiple sclerosis lesions brain images

Co-investigatorNSERC2010Collaborative Research and Development Grants

Principal investigators: Arbel, Tal

$173,752

Tissue segmentation in MRI

Principal investigatorNSERC2007Strategic Projects - Group

Principal investigators: Collins, Louis

$615,266

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Louis Collins

Research

Latest papers

Latest funding

Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline.

Human cortical organoids recapitulate inter-individual variability in infant brain-growth trajectories.

Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition.

A digital twin methodology using retrospective patient data for sample size reduction in Alzheimer's disease clinical trials.

Choroidal-ventricular system abnormalities are linked to amyloid-&#x3b2; aggregation in Alzheimer's disease.

Hippocampal-to-Ventricle Ratio as a Head-Size-Independent Biomarker: Sex Differences and Cognitive Associations in 27,680 UK Biobank Participants

DeformView: Quantitative Visualization of Non-Linear Deformation Fields

Sex Differences in the Alzheimer’s Brain Age Gap: APOE ε4 Plays a Major Role

DeformView: Quantitative Visualization of Non-Linear Deformation Fields

Brain age estimation pipeline: trained weights and Apptainer image (Rajabli et al., 2025)

The McConnell Brain Imaging Center: A world-renowned multidisciplinary platform dedicated to brain research using multimodal neuroimaging and neuroinformatics

Framework for multi-feature registration of medical images

CBRAIN: Canadian Brain Research And Informatics Platform

Drug Delivery across the Human Blood-Brain Barrier

Optical guidance for safe and effective brain tumor biopsy

Réseaux structurels et fonctionnels dans les troubles du spectre de l’autisme et le syndrome de l’X fragile

NSERC CREATE: Medical Physics Research Training Network (MPRTN)

NSERC CREATE Program in Medical Image Analysis

Probabilistic segmentation of multiple sclerosis lesions brain images

Tissue segmentation in MRI

Frequent collaborators

Donald Collins

Mallar Chakravarty

Alan Evans

Mahsa Dadar

Douglas Arnold

Simon Ducharme

Pedro Rosa-Neto

Jens Pruessner

John Breitner

Sridar Narayanan

Sylvia Villeneuve

Simon Duchesne

Gilbert Pike

Marta Kersten

Marta Kersten-Oertel

Simon Drouin

Judes Poirier

Alain Dagher

Tal Arbel

Christine Tardif

Jean-Paul Soucy

Cassandra Morrison

Lune Bellec

Christian Bocti

Richard Camicioli

Thanh Dang-Vu

Giulia Longoni

Lorne Zinman

Thien Vu

Joel Ramirez

Jérôme Paquet

Evan Wong

Alain Giguère

Roger Dixon

Anne Champod

Junchao Tong

Russel Schachar

Sylvain Houle

Charles Tator

Soufiane Boucetta

Choroidal-ventricular system abnormalities are linked to amyloid-β aggregation in Alzheimer's disease.