Faculty profile

Emmanuel Planel

ResearcherUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Emmanuel Planel

Researcher

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
16 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (4 CIHR, 3 NSERC), most recently in 2023.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Alzheimer'S Disease Biological Factors Environmental Factors Microtubules Protein Aggregation Tau Protein

Latest papers

Lifelong heat exposure as a potential contributor to Alzheimer's disease resilience.
Journal of Alzheimer's disease : JAD · 2026 · senior author
Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models.
British journal of pharmacology · 2025
Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel.
International journal of molecular sciences · 2025

All 57 publications

Latest funding

Regulation of amyloid processing by core body temperature rythms: Implication for Alzheimer's disease
CIHR · 2025 · Supervisor
$120,000
Physiological regulation of tau protein
NSERC · 2023 · Principal investigator
$80,000
Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease
CIHR · 2023 · Co-investigator
$990,675

All 15 grants and awards

57 publications.

Lifelong heat exposure as a potential contributor to Alzheimer's disease resilience.

Canet G, Lucey BP, Blessing EM, Planel E

Journal of Alzheimer's disease : JAD2026Senior author

DOI: 10.1177/13872877261433226 PMID: 41848374

Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models.

Canet G, Zussy C, Vitalis M, Morin F, Chevallier N, Hunt H, Claeysen S, Blaquière M, Marchi N, Planel E, Meijer OC, Desrumaux C, Givalois L

British journal of pharmacology2025

DOI: 10.1111/bph.17457 PMID: 39891319

Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel.

Godbout K, Dugas M, Reiken SR, Ramezani S, Falle A, Rousseau J, Wronska AE, Lamothe G, Canet G, Lu Y, Planel E, Marks AR, Tremblay JP

International journal of molecular sciences2025

DOI: 10.3390/ijms26072835 PMID: 40243436

Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions.

Paul PS, Rathnam M, Khalili A, Cortez LM, Srinivasan M, Planel E, Cho JY, Wille H, Sim VL, Mok SA, Kar S

International journal of nanomedicine2025

DOI: 10.2147/ijn.s494104 PMID: 39968061

Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau.

Canet G, Da Gama Monteiro F, Rocaboy E, Diego-Diaz S, Khelaifia B, Godbout K, Lachhab A, Kim J, Valencia DI, Yin A, Wu HT, Howell J, Blank E, Laliberté F, Fortin N, Boscher E, Fereydouni-Forouzandeh P, Champagne S, Guisle I, Hébert SS, Pernet V, Liu H, Lu W, Debure L, Rapoport DM, Ayappa I, Varga AW, Parekh A, Osorio RS, Lacroix S, Burns MP, Lucey BP, Blessing EM, Planel E

The Journal of clinical investigation2025Senior author

DOI: 10.1172/jci182931 PMID: 39903530

Proteostasis restoration: a new metric for tau immunotherapy efficacy.

Canet G, Planel E

Brain : a journal of neurology2025Senior author

DOI: 10.1093/brain/awae382 PMID: 39569440

Beneficial effects of miR-132/212 deficiency in the zQ175 mouse model of Huntington's disease.

Nateghi B, Keraudren R, Boulay G, Bazin M, Goupil C, Canet G, Loiselle A, St-Amour I, Planel E, Soulet D, Hébert SS

Frontiers in neuroscience2024

DOI: 10.3389/fnins.2024.1421680 PMID: 39170678

Age-dependent impact of streptozotocin on metabolic endpoints and Alzheimer's disease pathologies in 3xTg-AD mice.

Canet G, Gratuze M, Zussy C, Bouali ML, Diaz SD, Rocaboy E, Laliberté F, El Khoury NB, Tremblay C, Morin F, Calon F, Hébert SS, Julien C, Planel E

Neurobiology of disease2024Senior author

DOI: 10.1016/j.nbd.2024.106526 PMID: 38734152

Methods for Biochemical Isolation of Insoluble Tau in Rodent Models of Tauopathies.

Canet G, Rocaboy E, Diego-Diàz S, Whittington RA, Julien C, Planel E

Methods in molecular biology (Clifton, N.J.)2024Senior author

DOI: 10.1007/978-1-0716-3629-9_17 PMID: 38512674

Western Blot of Tau Protein from Mouse Brains Extracts: How to Avoid Signal Artifacts.

Fereydouni-Forouzandeh P, Canet G, Diego-Diàz S, Rocaboy E, Petry S, Whittington RA, Planel E

Methods in molecular biology (Clifton, N.J.)2024Senior author

DOI: 10.1007/978-1-0716-3629-9_16 PMID: 38512673

Regulation of amyloid processing by core body temperature rythms: Implication for Alzheimer's disease

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Godbout, Kelly

Keywords: Alzheimer'S Disease; Amyloid Beta Metabolism; Circadian Rhythms; Core Body Temperature; Neurodegeneration; Sleep-Wake Cycle; Thermoregulation

$120,000

Physiological regulation of tau protein

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Planel, Emmanuel

Keywords: Brain; Phosphorylation; Secretion; Splicing; Tau protein; Temperature

$80,000

Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease

Co-investigatorCIHR2023Project Grant

Principal investigators: Kar, Satyabrata

Keywords: Alzheimer'S Disease; Animal Models Of Alzheimer'S Disease; Cognitive Deficits; Induced Pluripotent Stem Cells; Native Nanoparticles; Neuroprotection; Neurotoxicity; Protein Aggregation; Protein Disaggregation; Tau Protein

$990,675

Microglial tau: a missing link between neuroinflammation and neurodegeneration in TDP-43 proteinopathies

Co-investigatorCIHR2022Project Grant

Principal investigators: Kriz, Jasna

Keywords: Cell Profiling; Dementias; Mab/Aso Therapies; Microglia; Neurodegeneration; Proteomics; Tau; Transgenic Disease Models

$952,425

3rd NeuroForum of the CHU de Québec-Université Laval Research Center: A seminar series of leaders in neuroscience

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Lacroix, Steve

Keywords: Annual Seminar; Collaboration; Dissemination; Knowledge Exchange; Neuroscience; Training

$7,614

Untangling tau contribution to cognitive impairments in Huntington's disease.

Co-investigatorCIHR2018Project Grant

Principal investigators: Cicchetti, Francesca

Keywords: Blood Samples; Cognitive Deficits; Huntington'S Disease Patients; Misfolded Proteins; Mouse Models; Neurodegenerative Diseases; Positron Emission Tomography

$1,044,225

Regulation of tau phosphorylation and splicing during post-embryonic development

Principal investigatorNSERC2016Discovery Grants Program - Individual

Principal investigators: Planel, Emmanuel

$198,000

Effects of perioperative factors on tau pathogenesis

SupervisorCIHR2016Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Bouchard, Amy

Keywords: Alzheimer'S Disease; Tau Pathology

$105,000

In Vivo Imaging System

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Shah, Girish

$150,000

Tau protein in neurobiology: regulation and deregulation in vivo.

Nominated PICIHR2012CIHR New Investigator

Principal investigators: Planel, Emmanuel

Keywords: Alzheimer'S Disease; Biological Factors; Environmental Factors; Microtubules; Protein Aggregation; Tau Protein

$300,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Emmanuel Planel

Research

Latest papers

Latest funding

Lifelong heat exposure as a potential contributor to Alzheimer's disease resilience.

Advancing Alzheimer's disease pharmacotherapy: efficacy of glucocorticoid modulation with dazucorilant (CORT113176) in preclinical mouse models.

Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel.

Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions.

Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau.

Proteostasis restoration: a new metric for tau immunotherapy efficacy.

Beneficial effects of miR-132/212 deficiency in the zQ175 mouse model of Huntington's disease.

Age-dependent impact of streptozotocin on metabolic endpoints and Alzheimer's disease pathologies in 3xTg-AD mice.

Methods for Biochemical Isolation of Insoluble Tau in Rodent Models of Tauopathies.

Western Blot of Tau Protein from Mouse Brains Extracts: How to Avoid Signal Artifacts.

Regulation of amyloid processing by core body temperature rythms: Implication for Alzheimer's disease

Physiological regulation of tau protein

Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease

Microglial tau: a missing link between neuroinflammation and neurodegeneration in TDP-43 proteinopathies

3rd NeuroForum of the CHU de Québec-Université Laval Research Center: A seminar series of leaders in neuroscience

Untangling tau contribution to cognitive impairments in Huntington's disease.

Regulation of tau phosphorylation and splicing during post-embryonic development

Effects of perioperative factors on tau pathogenesis

In Vivo Imaging System

Tau protein in neurobiology: regulation and deregulation in vivo.

Frequent collaborators

Francesca Cicchetti

Vincent Pernet

Frédéric Calon

André Marette

Steve Lacroix

Jean Charron

Sue-Ann Mok

Holger Wille

Arnaud Droit

Satyabrata Kar

Denis Soulet

Yves Giguere