Faculty profile

Sue-Ann Mok

ResearcherBiochemistryUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Sue-Ann Mok

Researcher

Biochemistry

Health Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (2 CIHR, 2 NSERC), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

High-Throughput Biochemical Assays Molecular Chaperones Protein Aggregation Protein Conformations Tau Tau Aggregate Spreading Tauopathies

Latest papers

Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry.
Proceedings of the National Academy of Sciences of the United States of America · 2026
A metabolite extracted from Escherichia coli suppresses tau aggregation.
The Biochemical journal · 2026 · senior author
DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.
Molecular neurodegeneration · 2025

All 24 publications

Latest funding

Systematic manipulation of tau protein aggregation: bridging biochemical and pathological properties
CIHR · 2023 · Nominated PI
$960,076
Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease
CIHR · 2023 · Co-investigator
$990,675
Systematic manipulation of tau protein aggregation: bridging biochemical and pathological properties
CIHR · 2022 · Nominated PI
$100,000

All 5 grants and awards

24 publications.

Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry.

Lyons A, Paul SS, MacArthur JE, Hoffman GN, Yarahmady A, Mok SA, Woodside MT

Proceedings of the National Academy of Sciences of the United States of America2026

DOI: 10.1073/pnas.2536600123 PMID: 42485386

A metabolite extracted from Escherichia coli suppresses tau aggregation.

Srinivasan M, Patel A, Patel T, Moore J, Gomez-Cardona E, Yarahmady A, Sykes BD, Julien O, Mok SA

The Biochemical journal2026Senior author

DOI: 10.1042/bcj20260068 PMID: 41983431

DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.

Chen H, Fan L, Guo Q, Wong MY, Zhu J, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Patel T, Mok SA, Song WM, Zhang B, Gong S, Ma Q, Fu H, Gan L, Luo W

Molecular neurodegeneration2025

DOI: 10.1186/s13024-025-00903-3 PMID: 41331787

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

Monyror J, Kadam V, Morales LC, Ordóñez D, Ibanga J, Zaidi AK, McNamara E, Pink D, Stenlund M, Reyes K, Maguire AD, Huang J, Cortez LM, Sim VL, Mok SA, Posse de Chaves E, Sipione S

Science advances2025

DOI: 10.1126/sciadv.ady5212 PMID: 40961208

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.

Naguib S, Lopez-Lee C, Torres ER, Lee SI, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MY, Ambaw YA, Muñoz-Castañeda R, Wang W, Patel T, Bhagwat M, Norinsky R, Mok SA, Walther TC, Farese RV, Luo W, Sinha SC, Wu Z, Fan L, Gong S, Gan L

Immunity2025

DOI: 10.1016/j.immuni.2025.05.023 PMID: 40555238

Inducers and modulators of protein aggregation in Alzheimer's disease - Critical tools for understanding the foundations of aggregate structures.

Sun KT, Mok SA

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2025Senior author

DOI: 10.1016/j.neurot.2024.e00512 PMID: 39755501

Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions.

Paul PS, Rathnam M, Khalili A, Cortez LM, Srinivasan M, Planel E, Cho JY, Wille H, Sim VL, Mok SA, Kar S

International journal of nanomedicine2025

DOI: 10.2147/ijn.s494104 PMID: 39968061

APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.

Naguib S, Lopez-Lee C, Torres ER, Lee SI, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MY, Ambaw YA, Castaneda R, Wang W, Patel T, Bhagwat M, Norinsky R, Mok SA, Walther TC, Farese RV, Luo W, Sinha S, Wu Z, Fan L, Gong S, Gan L

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2024.04.25.591140 PMID: 38712164

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

Carling GK, Fan L, Foxe NR, Norman K, Wong MY, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A, Ye P, Chen H, Huang Y, Amin S, Sereda R, Lopez-Lee C, Zacharioudakis E, Chen X, Xu J, Cheng F, Gavathiotis E, Cuervo AM, Holtzman DM, Mok SA, Sinha SC, Sidoli S, Ratan RR, Luo W, Gong S, Gan L

Neuron2024

DOI: 10.1016/j.neuron.2024.09.006 PMID: 39353433

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.

Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L

Cell2024

DOI: 10.1016/j.cell.2024.03.015 PMID: 38582079

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Sue-Ann Mok

Research

Latest papers

Latest funding

Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry.

A metabolite extracted from Escherichia coli suppresses tau aggregation.

DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.

Inducers and modulators of protein aggregation in Alzheimer's disease - Critical tools for understanding the foundations of aggregate structures.

Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions.

APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.

Systematic manipulation of tau protein aggregation: bridging biochemical and pathological properties

Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease

Systematic manipulation of tau protein aggregation: bridging biochemical and pathological properties

Cell-type specific wiring of the chaperone network

Cell-type specific wiring of the chaperone network

Frequent collaborators

Satyabrata Kar

Holger Wille

David Westaway

Emmanuel Planel

Simonetta Sipione

Paul LaPointe