Patrick Provost, Université Laval

Research

Gene Regulation Microrna Animal Model (Mice)Platelet Transfusion Bioinformatics Diet Food Sources

Latest papers

Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2
Viruses · 2023 · senior author
A tRNA-derived fragment present in E. coli OMVs regulates host cell gene expression and proliferation.
PLoS pathogens · 2022 · senior author
RNA Sequencing Unveils Very Small RNAs With Potential Regulatory Functions in Bacteria.
Frontiers in molecular biosciences · 2022 · senior author

All 42 publications

Latest funding

A novel class of small non-coding RNAs
NSERC · 2019 · Principal investigator
$210,000
A unique model to assess the oral transfer of dietary microRNAs
CIHR · 2019 · Nominated PI
$454,410
In Vivo Imaging System
NSERC · 2014 · Co-investigator
$150,000

All 14 grants and awards

42 publications.

01

Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2

Diallo I, Jacob RA, Vion E, Kozak RA, Mossman K, Provost P

Viruses20238 citationsSenior author

DOI: 10.3390/v15020496

02

A tRNA-derived fragment present in E. coli OMVs regulates host cell gene expression and proliferation.

Diallo I, Ho J, Lambert M, Benmoussa A, Husseini Z, Lalaouna D, Massé E, Provost P

PLoS pathogens2022Senior author

DOI: 10.1371/journal.ppat.1010827 PMID: 36108089

03

RNA Sequencing Unveils Very Small RNAs With Potential Regulatory Functions in Bacteria.

Diallo I, Ho J, Lalaouna D, Massé E, Provost P

Frontiers in molecular biosciences2022Senior author

DOI: 10.3389/fmolb.2022.914991 PMID: 35720117

04

An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms.

Lambert M, Guellal S, Ho J, Benmoussa A, Laffont B, Bélanger R, Provost P

Non-coding RNA2022Senior author

DOI: 10.3390/ncrna8030034 PMID: 35645341

05

Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells.

Diallo I, Husseini Z, Guellal S, Vion E, Ho J, Kozak RA, Kobinger GP, Provost P

International journal of molecular sciences2022Senior author

DOI: 10.3390/ijms23095228 PMID: 35563619

06

A New Specific and Sensitive RT-qPCR Method Based on Splinted 5' Ligation for the Quantitative Detection of RNA Species Shorter than microRNAs.

Lambert M, Benmoussa A, Provost P

Non-coding RNA2021Senior author

DOI: 10.3390/ncrna7030059 PMID: 34564321

07

Identification of Abundant and Functional dodecaRNAs (doRNAs) Derived from Ribosomal RNA.

Lambert M, Benmoussa A, Diallo I, Ouellet-Boutin K, Dorval V, Majeau N, Joly-Beauparlant C, Droit A, Bergeron A, Têtu B, Fradet Y, Pouliot F, Provost P

International journal of molecular sciences2021Senior author

DOI: 10.3390/ijms22189757 PMID: 34575920

08

Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA.

Vaillancourt M, Hubert A, Subra C, Boucher J, Bazié WW, Vitry J, Berrazouane S, Routy JP, Trottier S, Tremblay C, Jenabian MA, Benmoussa A, Provost P, Tessier PA, Gilbert C

Pathogens (Basel, Switzerland)2021

DOI: 10.3390/pathogens10050526 PMID: 33925397

09

Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition.

Maghraby MK, Li B, Chi L, Ling C, Benmoussa A, Provost P, Postmus AC, Abdi A, Pierro A, Bourdon C, Bandsma RHJ

Scientific reports2021

DOI: 10.1038/s41598-021-86920-w PMID: 33828139

10

Altered microRNA Transcriptome in Cultured Human Liver Cells upon Infection with Ebola Virus.

Diallo I, Ho J, Laffont B, Laugier J, Benmoussa A, Lambert M, Husseini Z, Soule G, Kozak R, Kobinger GP, Provost P

International journal of molecular sciences2021Senior author

DOI: 10.3390/ijms22073792 PMID: 33917562

A novel class of small non-coding RNAs

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Provost, Patrick

$210,000

A unique model to assess the oral transfer of dietary microRNAs

Nominated PICIHR2019Project Grant

Principal investigators: Provost, Patrick

Keywords: Aging; Colitis; Cow; Digestion; Extracellular Vesicles; Gene Regulation; Mice; Microrna; Milk; Oral Delivery

$454,410

In Vivo Imaging System

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Shah, Girish

$150,000

Release, delivery and cell programming effects of platelet microparticles and microRNAs

Nominated PICIHR2014Operating Grant - Priority Announcement: Blood Utilization and Conservation

Principal investigators: Provost, Patrick

Keywords: Animal Model (Mice); Cardiovascular Disease; Endothelial Cell; Gene Regulation; Macrophages; Microparticle; Microrna; Mitochondria; Platelet; Transfusion

Dietary microRNAs

Nominated PICIHR2014Operating Grant

Principal investigators: Provost, Patrick

Keywords: Animal Model (Mice); Bioinformatics; Diet; Food Sources; Gene Regulation; Human Health; Microrna; Nutrition

$237,254

Dietary microRNAs

Nominated PICIHR2013Operating Grant - PA: Institute of Genetics (Bridge Funding)

Principal investigators: Provost, Patrick

Keywords: Animal Model (Mice); Bioinformatics; Diet; Food Sources; Gene Regulation; Human Health; Microrna; Nutrition

$100,000

Role, function and regulation of human Dicer

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Provost, Patrick

$215,000

""Role, function and regulation of human Dicer""

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Provost, Patrick

$28,000

Platelet microRNAs during storage under blood bank conditions

Nominated PICIHR2012Operating Grant - Priority Announcement: Blood Utilization and Conservation

Principal investigators: Provost, Patrick

Keywords: Blood Storage; Dicer; Gene Regulation; Microrna; Pathogen Reduction; Platelet; Transfusion

Alteration of the microRNA pathway during the aging process

Nominated PICIHR2010Catalyst Grant: Pilot Projects in Aging - Biological & Clinical Aspects of Aging

Principal investigators: Provost, Patrick

Keywords: Aging; Argonaute 2; Biochemistry; Cell Culture; Chemical Agents; Dicer; Gene Regulation; Microrna; Molecular Biology; Rna Silencing

$50,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Microbiologie et immunologie
Surgery
Médecine sociale et préventive
Infectious Diseases
Molecular Medicine
Other

Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Eric Boilard

Microbiologie et immunologie

6 shared papers, latest 2018

Arnaud Droit

Microbiologie et immunologie

2 shared papers, latest 2021

Marc Pouliot

Microbiologie et immunologie

1 shared papers, latest 2015

Serge Rivest

Molecular Medicine

1 shared papers, latest 2009

Robert Kozak

Infectious Diseases

1 shared papers, latest 2021

Michel Alary

Médecine sociale et préventive

1 shared papers, latest 2021

Denis Soulet

Faculty

1 shared papers, latest 2015

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2019

Subject: Prospective PhD student: Gene Regulation Dear Professor Provost, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2" (2023), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "A novel class of small non-coding RNAs" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Patrick Provost

Research

Latest papers

Latest funding

Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2

A tRNA-derived fragment present in E. coli OMVs regulates host cell gene expression and proliferation.

RNA Sequencing Unveils Very Small RNAs With Potential Regulatory Functions in Bacteria.

An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms.

Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells.

A New Specific and Sensitive RT-qPCR Method Based on Splinted 5' Ligation for the Quantitative Detection of RNA Species Shorter than microRNAs.

Identification of Abundant and Functional dodecaRNAs (doRNAs) Derived from Ribosomal RNA.

Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA.

Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition.

Altered microRNA Transcriptome in Cultured Human Liver Cells upon Infection with Ebola Virus.

A novel class of small non-coding RNAs

A unique model to assess the oral transfer of dietary microRNAs

In Vivo Imaging System

Release, delivery and cell programming effects of platelet microparticles and microRNAs

Dietary microRNAs

Dietary microRNAs

Role, function and regulation of human Dicer

""Role, function and regulation of human Dicer""

Platelet microRNAs during storage under blood bank conditions

Alteration of the microRNA pathway during the aging process

Frequent collaborators

Caroline Gilbert

Eric Boilard

Jean-Pierre Routy

Arnaud Droit

Marc Pouliot

Mohammad-Ali Jenabian

Serge Rivest

Robert Kozak

Michel Alary

Agostino Pierro

Catherine Martel

Karen Mossman

Denis Soulet