Srinivas Murthy, Université Laval

Research

Adaptive Clinical Trials Capacity Building Consent Emergency Medicine Ethics Health Crisis Preparedness Implementation Science Pandemic Preparedness

Latest papers

Simvastatin in Critically Ill Patients with Covid-19.
The New England journal of medicine · 2023
Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial
CANADIAN MEDICAL ASSOCIATION JOURNAL · 2022
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
The New England journal of medicine · 2021

All 5 publications

Latest funding

BRAINapt: TBI International Adaptive Platform Trial
CIHR · 2023 · Co-investigator
$100,000
Expanding the Patient-Oriented Research Capacity of the Canadian Emergency Department Rapid Response Network (CEDRRN) to Enable Patient-Centered Adaptive Platform Trials and Ensure Health Crisis Preparedness
CIHR · 2023 · Principal investigator
$199,935
Anticoagulation and Convalescent Plasma ICU Trials in REMAP-CAP
CIHR · 2020 · Co-investigator
$2,176,566

All 3 grants and awards

5 publications.

01

Simvastatin in Critically Ill Patients with Covid-19.

REMAP-CAP Investigators, Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF

The New England journal of medicine2023

DOI: 10.1056/nejmoa2309995 PMID: 37888913

02

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

Ali K, Azher T, Baqi M, Binnie A, Borgia S, Carrier FM, Cavayas YA, Chagnon N, Cheng MP, Conly J

CANADIAN MEDICAL ASSOCIATION JOURNAL2022173 citations

DOI: 10.1503/cmaj.211698

03

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.

REMAP-CAP Investigators, Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Berry LR, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Buzgau A, Cheng AC, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Goossens H, Haniffa R, Higgins AM, Hills TE, Horvat CM, Lamontagne F, Lawler PR, Leavis HL, Linstrum KM, Litton E, Lorenzi E, Marshall JC, Mayr FB, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Montgomery SK, Morpeth SC, Murthy S, Orr K, Parke RL, Parker JC, Patanwala AE, Pettilä V, Rademaker E, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Webb SA, Derde LPG

The New England journal of medicine2021

DOI: 10.1056/nejmoa2100433 PMID: 33631065

04

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Effron MB, Berger JS, Gong MN, Kumar A, Kahn SR, McQuilten Z, Farkouh ME, Brooks MM, Lewis RJ, Berry LR

New England Journal of Medicine2021922 citations

DOI: 10.1056/nejmoa2103417

05

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

Chen J-T, Effron MB, Silva DG, Berger JS, Gong MN, Rosenson RS, Kumar A, Kahn SR, Cushman M, McQuilten Z

New England Journal of Medicine2021894 citations

DOI: 10.1056/nejmoa2105911

BRAINapt: TBI International Adaptive Platform Trial

Co-investigatorCIHR2023Project Grant

Principal investigators: Turgeon, Alexis F; English, Shane W; Lauzier, François; McDonald, Michelle; Moore, Lynne; Park, Jay; Zarychanski, Ryan

Keywords: Critical Care Medicine; Intensive Care Medicine; Multicenter Trial; Neurocritical Care; Platform Trial; Traumatic Brain Injury

$100,000

Expanding the Patient-Oriented Research Capacity of the Canadian Emergency Department Rapid Response Network (CEDRRN) to Enable Patient-Centered Adaptive Platform Trials and Ensure Health Crisis Preparedness

Principal investigatorCIHR2023Catalyst Grant: SPOR Innovative Clinical Trials (iCT)

Principal investigators: Archambault, Patrick; Bergman, Howard; Graves, Donna Lorraine; Morris, Judy M; de Wit, Kerstin; Hohl, Corinne M; Lang, Eddy S; Leeies, Murdoch A; McLeod, Shelley L; McRae, Andrew D; Morrison, Laurie J; Murthy, Srinivas

Keywords: Adaptive Clinical Trials; Capacity Building; Consent; Emergency Medicine; Ethics; Health Crisis Preparedness; Implementation Science; Pandemic Preparedness; Patient-Oriented Research; Priority Setting

$199,935

Anticoagulation and Convalescent Plasma ICU Trials in REMAP-CAP

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Turgeon, Alexis F; Paunovic, Bojan; Zarychanski, Ryan

Keywords: Clinical Applied Research; Critical Care Medicine; Intensive Care Medicine; Intervention; Multicenter Research; Randomized Controlled Trials

$2,176,566

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Critical Care Medicine
Internal Medicine
Family Medicine and Emergency Medicine
Anesthesiology & Critical Care Medicine
Pharmacology and Therapeutics
Médecine interne
Other

1 shared papers, latest 2022

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Applying for

Paper to mentionMention their CIHR grant from 2023

Subject: Prospective PhD student: Adaptive Clinical Trials Dear Professor Murthy, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Simvastatin in Critically Ill Patients with Covid-19." (2023), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Expanding the Patient-Oriented Research Capacity of the Canadian Emergency Department Rapid Response Network (CEDRRN) to Enable Patient-Centered Adaptive Platform Trials and Ensure Health Crisis Preparedness" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]