Faculty profile

Srinivas Murthy

ResearcherCritical Care MedicineUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Srinivas Murthy

Researcher

Critical Care Medicine

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
2 publications in the last five years, latest in 2023.
Principal investigator on 14 research grants (14 CIHR), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

2,040

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Covid-19 Randomized Controlled Trial Adaptive Platform Trial Critical Illness Clinical Trials Network Bacteria Infection

Latest papers

Simvastatin in Critically Ill Patients with Covid-19.
The New England journal of medicine · 2023
Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial
CANADIAN MEDICAL ASSOCIATION JOURNAL · 2022
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19
New England Journal of Medicine · 2021

All 14 publications

Latest funding

REduced-dose Steroid PrOtocol for childhood Nephrotic SyndromE (RESPONSE): a Multicentre Bayesian Adaptive Randomized Controlled Trial
CIHR · 2025 · Co-investigator
$150,000
BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections
CIHR · 2025 · Co-investigator
$1,908,674
Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis (DOC): a Pilot Randomized Clinical Trial
CIHR · 2025 · Co-investigator
$417,012

All 30 grants and awards

14 publications.

Simvastatin in Critically Ill Patients with Covid-19.

REMAP-CAP Investigators, Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF

The New England journal of medicine2023

DOI: 10.1056/nejmoa2309995 PMID: 37888913

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

Ali K, Azher T, Baqi M, Binnie A, Borgia S, Carrier FM, Cavayas YA, Chagnon N, Cheng MP, Conly J

CANADIAN MEDICAL ASSOCIATION JOURNAL2022173 citations

DOI: 10.1503/cmaj.211698

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Effron MB, Berger JS, Gong MN, Kumar A, Kahn SR, McQuilten Z, Farkouh ME, Brooks MM, Lewis RJ, Berry LR

New England Journal of Medicine2021922 citations

DOI: 10.1056/nejmoa2103417

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

Chen J-T, Effron MB, Silva DG, Berger JS, Gong MN, Rosenson RS, Kumar A, Kahn SR, Cushman M, McQuilten Z

New England Journal of Medicine2021894 citations

DOI: 10.1056/nejmoa2105911

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.

REMAP-CAP Investigators, Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Berry LR, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Buzgau A, Cheng AC, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Goossens H, Haniffa R, Higgins AM, Hills TE, Horvat CM, Lamontagne F, Lawler PR, Leavis HL, Linstrum KM, Litton E, Lorenzi E, Marshall JC, Mayr FB, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Montgomery SK, Morpeth SC, Murthy S, Orr K, Parke RL, Parker JC, Patanwala AE, Pettilä V, Rademaker E, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Webb SA, Derde LPG

The New England journal of medicine2021

DOI: 10.1056/nejmoa2100433 PMID: 33631065

Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline

Ye Z, Rochwerg B, Wang Y, Adhikari NK, Murthy S, Lamontagne F, Fowler RA, Qiu H, Wei L, Sang L

CANADIAN MEDICAL ASSOCIATION JOURNAL202051 citations

DOI: 10.1503/cmaj.200648

Innominate artery aneurysm after cannulation for extracorporeal membrane oxygenation via the right carotid artery.

Murthy S, MacDonald C, Honjo O, Floh AA, Humpl T

Intensive care medicine2013First author

DOI: 10.1007/s00134-013-3070-1 PMID: 23963473

Global health care of the critically ill in low-resource settings.

Murthy S, Adhikari NK

Annals of the American Thoracic Society2013First author

DOI: 10.1513/annalsats.201307-246ot PMID: 24161054

Infections of the developing world.

Murthy S, Keystone J, Kissoon N

Critical care clinics2013First author

DOI: 10.1016/j.ccc.2013.03.005 PMID: 23830650

Analysis of pediatric clinical drug trials for neuropsychiatric conditions.

Murthy S, Mandl KD, Bourgeois F

Pediatrics2013First author

DOI: 10.1542/peds.2012-2694 PMID: 23650305

REduced-dose Steroid PrOtocol for childhood Nephrotic SyndromE (RESPONSE): a Multicentre Bayesian Adaptive Randomized Controlled Trial

Co-investigatorCIHR2025Operating Grant: ECRs in Human Development, Child and Youth Health

Principal investigators: Robinson, Cal; Parekh, Rulan S

Keywords: Adaptive Clinical Trial; Bayesian Statistics; Children; Corticosteroids; Nephrotic Syndrome; Pediatric; Randomized Controlled Trial; Steroid-Sensitive Nephrotic Syndrome

$150,000

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2025Project Grant

Principal investigators: Daneman, Nick; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Ong, Sean W; Pinto, Ruxandra; Rogers, Benjamin A

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Duration; Antibiotic Oral Switch; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Clinical Trial

$1,908,674

Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis (DOC): a Pilot Randomized Clinical Trial

Co-investigatorCIHR2025Project Grant

Principal investigators: Gill, Peter J; Buchanan, Francine; Mahant, Sanjay

Keywords: Child Health; Clinical Epidemiology; Dexamethasone; Feasibility; General Pediatrics; Hospital Medicine; Orbital Cellulitis; Patient Oriented Research; Pilot Study; Randomized Controlled Trial

$417,012

Dexamethasone vs. Placebo in Children and Youth Hospitalized for Orbital Cellulitis (DOC): a Pilot Randomized Clinical Trial

Co-investigatorCIHR2024Operating Grant: ECRs in Human Development, Child and Youth Health

Principal investigators: Gill, Peter J; Buchanan, Francine; Mahant, Sanjay

$149,866

The Randomized Embedded Multifactorial Adaptive Platform Trial in Community-Acquired Pneumonia (REMAP-CAP): Enshrining a Global Pandemic Research Response to COVID-19 and Beyond

Principal investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Marshall, John C; Dalziel, Sandra; Kho, Michelle E; Lamontagne, Francois; Leligdowicz, Aleksandra; Murthy, Srinivas; Park, Jay; Smith, Kathleen F

Keywords: Acute Organ Dysfunction; Covid-19; Critical Illness; Global Health; Hemodynamic Management; Platform Trial; Research Collaboration; Ventilatory Support

$883,029

Establishing Feasibility & Safety of Providing Critical Care Treatments for Patients with Ebola in a Simulated Ebola Treatment Centre: Phase 2

Co-investigatorCIHR2022Project Grant

Principal investigators: Fowler, Robert A; Adhikari, Neill K

Keywords: Clinical Trial; Ebola; Heat; Outbreak; Pandemic; Simulation

$248,625

The Brain after Extracorporeal Membrane Oxygenation (ECMO): Long-Term Outcomes in Survivors Treated During Childhood

Co-investigatorCIHR2022Project Grant - Priority Announcement: Patient-Oriented Research

Principal investigators: Guerguerian, Anne-Marie

Keywords: Brain Imaging; Cardiovascular Outcome; Ecmo; Headache; Health Related Quality Of Life; Neurologic Outcome; Patient Oriented Outcome; Pediatric Critical Care Illness; Vascular Outcome

$100,000

Canadian Critical Care Trials Group COVID-19 Response: defining critical care capacity in Canada; testing treatments through large-scale adaptive clinical trials; & establishing the evidence base to inform clinical and health system management decisions

Principal investigatorCIHR2022Operating Grant: CNCCTN Extension - Indirect Costs

Principal investigators: Fowler, Robert A; Adhikari, Neill K; Archambault, Patrick; Bagshaw, Sean M; Binnie, Alexandra; Chasse, Michael; Cook, Deborah J; Daneman, Nick; Fiest, Kirsten M; Fox-Robichaud, Alison E; Goligher, Ewan C; Herridge, Margaret S; Kho, Michelle E; Lamontagne, Francois; Lawler, Patrick R; Lee, Todd C; Marshall, John C; McDonald, Emily G; McNally, James D; Meade, Maureen O; Mehta, Sangeeta; Menon, Kusum; Murthy, Srinivas; O'Hearn, Katharine J; Piquette, Dominique; Rochwerg, Bram N; Russell, James A; Tsang, Jennifer L; Turgeon, Alexis F; Wollny, Krista; Yada, Nicole; Zarychanski, Ryan

Keywords: Clinical Trials; Covid-19; Network

$1,000,000

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Principal investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Daneman, Nick; Murthy, Srinivas; Yamamura, Deborah L; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Paterson, David L; Rogers, Benjamin A; Yahav, Dafna

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Step-Down; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Controlled Trial

$729,947

A survey of Canadian critical care staffing to inform current policy and future need

Co-investigatorCIHR2022Cat Gr:Policy Res. for Health Sys. Transf.- ICRH - Circulatory and Resp. Health

Principal investigators: Wunsch, Hannah; Burns, Karen E; Gershengorn, Hayley

Keywords: Circulatory And Respiratory Health; Intensive Care Unit; Staffing

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Srinivas Murthy

Research

Latest papers

Latest funding

Simvastatin in Critically Ill Patients with Covid-19.

Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.

Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline

Innominate artery aneurysm after cannulation for extracorporeal membrane oxygenation via the right carotid artery.

Global health care of the critically ill in low-resource settings.

Infections of the developing world.

Analysis of pediatric clinical drug trials for neuropsychiatric conditions.

Frequent collaborators

Srinivas Murthy

Ryan Zarychanski

Ryan Zarychanski

Srinivas Murthy

Srinivas Murthy

Ryan Zarychanski

Francois Lamontagne

Francois Lamontagne

Jorge Escobedo

Marc Carrier

Anand Kumar

Marc Carrier

Sean van Diepen

Anand Kumar

Peter Lawrence Gross

Deborah Siegal

Gloria Vazquez-Grande

Mansoor Husain

Francois Lamontagne

Shane English

Haibo Qiu

Alexandra Binnie

Jennifer Tsang

Kevin Schwartz

Nick Daneman

Yoav Keynan

Jason Weatherald

Ying Wang

Sergio Borgia

Karim Ali

Patricia Fontela

Bram Rochwerg

Alexis Turgeon

Cecilia Costiniuk

Marina Klein

Fang Liu

Jennifer Tsang

Marina Klein

Hannah Wunsch

Mark Loeb