Faculty profile

Christine Vande Velde

ResearcherNeurosciencesUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Christine Vande Velde

Researcher

Neurosciences

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
11 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (5 CIHR, 5 NSERC), most recently in 2025.
Supervised 3 trainees who won CIHR awards, most recently in 2020.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Amyotrophic Lateral Sclerosis Cell Biology Stress Granules Tdp-43 Neurodegeneration Rna Binding Proteins Frontotemporal Dementia Mechanisms Of Disease

Latest papers

Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
Molecular therapy : the journal of the American Society of Gene Therapy · 2026
TARDBP (TDP-43) Knock-in Zebrafish Display a Late-Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons.
Annals of neurology · 2026
Dissolving stress granules.
Nature chemical biology · 2025 · senior author

All 22 publications

Latest funding

Dual regulation of the ALS/FTD relevant target G3BP1
CIHR · 2025 · Nominated PI
$1,193,400
An integrated approach to evaluate and modulate neuronal activity
NSERC · 2024 · Principal investigator
$150,000
Unravelling the physiological function of a highly conserved HNRNPA1 splice variant
NSERC · 2022 · Principal investigator
$120,000

All 14 grants and awards

22 publications.

Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.

Cueva Vargas JL, Belforte N, Vidal-Paredes IA, Dotigny F, Vande Velde C, Quintero H, Di Polo A

Molecular therapy : the journal of the American Society of Gene Therapy2026

DOI: 10.1016/j.ymthe.2025.09.037 PMID: 40994007

TARDBP (TDP-43) Knock-in Zebrafish Display a Late-Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons.

Harji ZA, Rampal CJ, Rodríguez EC, Petel Légaré V, Lissouba A, Semmler S, Liao M, Ross JP, Rouleau GA, Vande Velde C, Armstrong GAB

Annals of neurology2026

DOI: 10.1002/ana.78012 PMID: 40862353

Dissolving stress granules.

Dubinski A, Vande Velde C

Nature chemical biology2025Senior author

DOI: 10.1038/s41589-025-01979-0 PMID: 40715482

The differential impact of HNRNPA1 isoforms on gene expression and their relevance to dsRNA-mediated innate immune response.

Deshaies JE, Triassi V, Lacombe A, Gagné M, Ling K, Ghosh A, Labrecque M, Rigo F, Jafar-Nejad P, Tétreault M, Vande Velde C

Scientific reports2025Senior author

DOI: 10.1038/s41598-025-99031-7 PMID: 40312500

Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.

Cueva-Vargas JL, Belforte N, Vidal-Paredes IA, Dotigny F, Vande Velde C, Quintero H, Di Polo A

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2024.12.21.629919 PMID: 39975311

Patient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study.

Genuis SK, Luth W, Magnussen C, Vande Velde C, Taylor D, CAPTURE ALS Participant Partner Advisory Council, Johnston WS

Amyotrophic lateral sclerosis & frontotemporal degeneration2024

DOI: 10.1080/21678421.2024.2328599 PMID: 38519870

Amyotrophic lateral sclerosis: exploring pathophysiology in the context of treatment.

Genge A, Wainwright S, Vande Velde C

Amyotrophic lateral sclerosis & frontotemporal degeneration2024Senior author

DOI: 10.1080/21678421.2023.2278503 PMID: 38001557

The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis.

Fakim H, Vande Velde C

Seminars in cell & developmental biology2024Senior author

DOI: 10.1016/j.semcdb.2023.05.006 PMID: 37268555

ALCAM on human oligodendrocytes mediates CD4 T cell adhesion.

Jamann H, Desu HL, Cui QL, Halaweh A, Tastet O, Klement W, Zandee S, Pernin F, Mamane VH, Ouédraogo O, Daigneault A, Sidibé H, Millette F, Peelen E, Dhaeze T, Hoornaert C, Rébillard RM, Thai K, Grasmuck C, Vande Velde C, Prat A, Arbour N, Stratton JA, Antel J, Larochelle C

Brain : a journal of neurology2024

DOI: 10.1093/brain/awad286 PMID: 37640028

A new way to mitigate pathological Tau?

Ghosh A, Vande Velde C

Neuron2023Senior author

DOI: 10.1016/j.neuron.2023.08.001 PMID: 37678165

Dual regulation of the ALS/FTD relevant target G3BP1

Nominated PICIHR2025Project Grant

Principal investigators: Vande Velde, Christine Diane C

Keywords: Amyotrophic Lateral Sclerosis; Cell Biology; Frontotemporal Dementia; Mechanisms Of Disease; Neurodegeneration; Neurons; Rna Binding Proteins; Stress Granules; Tdp-43; Transgenic Mice

$1,193,400

An integrated approach to evaluate and modulate neuronal activity

Principal investigatorNSERC2024Research Tools and Instruments

Principal investigators: Vande Velde, Christine

Keywords: electrophysiology; mouse models; neurometabolism; neuronal activity; neurons; neurotransmission; RNA binding proteins; stereotaxic injections

$150,000

Unravelling the physiological function of a highly conserved HNRNPA1 splice variant

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Vande Velde, Christine

$120,000

Investigation of the Interplay between Stress and Genetics in Amyotrophic Lateral Sclerosis

SupervisorCIHR2020Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Dubinski, Alicia

Keywords: Amyotrophic Lateral Sclerosis (Als); Motor Neuron; Mouse Models; Neurodegeneration; Rna Binding Proteins; Rnp Granules; Stress Granules; Tdp-43

$105,000

UNDERSTANDING G3BP1 AND STRESS GRANULE DYNAMICS IN ALS PATHOGENESIS

Nominated PICIHR2019Project Grant

Principal investigators: Vande Velde, Christine Diane C

Keywords: Amyotrophic Lateral Sclerosis; Cell Biology; Environmental Stress; Neurodegeneration; Polyadenylation; Proteomics; Rna Binding Proteins; Rna Metabolism; Rna Stability; Stress Granules

$845,325

High performance nucleofection unit for difficult to manipulate cell types

Principal investigatorNSERC2017Research Tools and Instruments

Principal investigators: VandeVelde, Christine

$45,743

Cross regulation of RNA Binding Proteins and Ordered Protein Aggregation

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: VandeVelde, Christine

$170,000

Cell biological mechanisms of TDP-43 in amyotrophic lateral sclerosis

Nominated PICIHR2012Operating Grant - Priority Announcement: Neuromuscular Research

Principal investigators: Vande Velde, Christine Diane C

Keywords: Amyotrophic Lateral Sclerosis; Astrocyte; Cell Biology; Motor Neuron; Oxidative Stress; Stress Granules; Stress Response; Tdp-43

$11,684

Impact of TDP-43 in stress granule signaling in ALS

Nominated PICIHR2011CIHR New Investigator

Principal investigators: Vande Velde, Christine Diane C

Keywords: Amyotrophic Lateral Sclerosis; Biochemistry; Oxidative Stress; Rna-Binding Protein; Spinal Cord; Stress Granules; Tdp-43

$300,000

Emerging Team to identify and characterize novel and existing Hereditary Spastic Paraplegia (HSP) disease genes.

Co-investigatorCIHR2011Emerging Team Grant: Rare Diseases - Basic/Clinical

Principal investigators: Rouleau, Guy A

Keywords: Drug Screening; Exome Sequencing; Functional Studies; Gene Identification; Genetic Testing; Hereditary Spastic Paraplegia; Mutation Detection; Standardisation Of Diagnosis

$2,498,718

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Christine Vande Velde

Research

Latest papers

Latest funding

Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.

TARDBP (TDP-43) Knock-in Zebrafish Display a Late-Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons.

Dissolving stress granules.

The differential impact of HNRNPA1 isoforms on gene expression and their relevance to dsRNA-mediated innate immune response.

Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.

Patient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study.

Amyotrophic lateral sclerosis: exploring pathophysiology in the context of treatment.

The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis.

ALCAM on human oligodendrocytes mediates CD4 T cell adhesion.

A new way to mitigate pathological Tau?

Dual regulation of the ALS/FTD relevant target G3BP1

An integrated approach to evaluate and modulate neuronal activity

Unravelling the physiological function of a highly conserved HNRNPA1 splice variant

Investigation of the Interplay between Stress and Genetics in Amyotrophic Lateral Sclerosis

UNDERSTANDING G3BP1 AND STRESS GRANULE DYNAMICS IN ALS PATHOGENESIS

High performance nucleofection unit for difficult to manipulate cell types

Cross regulation of RNA Binding Proteins and Ordered Protein Aggregation

Cell biological mechanisms of TDP-43 in amyotrophic lateral sclerosis

Impact of TDP-43 in stress granule signaling in ALS

Emerging Team to identify and characterize novel and existing Hereditary Spastic Paraplegia (HSP) disease genes.

Frequent collaborators

Alexandre Prat

Adriana Di Polo

Jack Antel

Nathalie Arbour

Janice Robertson

Angela Genge

Catherine Larochelle

Pierre Drapeau

Nahum Sonenberg